CA2127458C - Spiral stent - Google Patents
Spiral stentInfo
- Publication number
- CA2127458C CA2127458C CA002127458A CA2127458A CA2127458C CA 2127458 C CA2127458 C CA 2127458C CA 002127458 A CA002127458 A CA 002127458A CA 2127458 A CA2127458 A CA 2127458A CA 2127458 C CA2127458 C CA 2127458C
- Authority
- CA
- Canada
- Prior art keywords
- stent
- self
- bends
- expanding stent
- helix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30462—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements retained or tied with a rope, string, thread, wire or cable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00017—Iron- or Fe-based alloys, e.g. stainless steel
Abstract
A self-expanding endovascular stent formed of stainless steel wire which is bent into an elongated zigzag pattern (5) and helically wound about a central axis (31) to define a tubular shape (30). Adjacent bends (8) in the helix are interconnected with a filament (32). The stent (30) is capable of being radially compressed such that the straight wire sections (11, 13 and 15), and the bends (8) are tightly packed around a central axis (31). The stent (30) resiliently self-expands to assume a tubular shape when released from the compressed state.
Description
2127~58 SPlR~J. ~l~N I --B~CKGR~UND OF Tll~ INV~N'1'10N
This invention relate~ generally to selr-e~pandin~
endovascular stents for use in preventillg restenosis o~
-5 passageways and ducts in the ~o~y, to repair anell1ysllls per~utaneously, and also for dilating recurring sten()sis immediately after attempts with ball~oning.
Tllis invention represellts an improvelnent in t~le self-expanding stents descri~ed an~ ShOWII in U.S. E~aterlt Nv.
4,5~0,568 to ~ianturco. Conventiona1 s~ellts of this type include a wire ~or~ned in a closed ziyzag configurat;lon that includes arl endless serie.s of straiy~lt sectio1ls joined by berl~s. A conventional ~ig~acJ stel~t is resiliellt1y compressible into a small diameter such ~hat tl~e straiglll:
secti~ns a1-e arranged si~e by side an~ closely adjacellt one anot~ler for insertion into a pas.sageway. The stent ifi resiliently self-expan(lable into a larger second diarne~er wllerein the straiyllt sections press against tlle wal~s of the passageway to maintain it open. Althou~h conventional zigzag stents l~ave proven quite useflll in m~ny situations, ~hei ~
per~ormance c:llarac~eristic.~ tend to decrease as the length ~f the s~ellt incr:eases.
Self-expandincJ stents are norlllally e~aluated with res~ect;
to four pel~or(llallce c~laracleristic.s: the ra~lially o-lt~a1d exE~an.sile force that t}le stellt exerts 011 the vascular wall;
t~le small dialneter ~o which tl~e .stent is c~pable of beiny conlpressed for the insert:iol- proceduLe; ~he ability of tlle sl:ent to ad~pt to cnrved p assa~eways in the patiellt: ~ s bocly; -I and ttle stabi1ity of the stcnt in not migral.irl~ Lroln its oricJillal-ly iln~ nted position withirl tlle ~atiellt.
Collvellt.iorlal ~ J st:~nts must no~lnally l)e macle W093/13825 PCT/US93/00355 ~ ~
This invention relate~ generally to selr-e~pandin~
endovascular stents for use in preventillg restenosis o~
-5 passageways and ducts in the ~o~y, to repair anell1ysllls per~utaneously, and also for dilating recurring sten()sis immediately after attempts with ball~oning.
Tllis invention represellts an improvelnent in t~le self-expanding stents descri~ed an~ ShOWII in U.S. E~aterlt Nv.
4,5~0,568 to ~ianturco. Conventiona1 s~ellts of this type include a wire ~or~ned in a closed ziyzag configurat;lon that includes arl endless serie.s of straiy~lt sectio1ls joined by berl~s. A conventional ~ig~acJ stel~t is resiliellt1y compressible into a small diameter such ~hat tl~e straiglll:
secti~ns a1-e arranged si~e by side an~ closely adjacellt one anot~ler for insertion into a pas.sageway. The stent ifi resiliently self-expan(lable into a larger second diarne~er wllerein the straiyllt sections press against tlle wal~s of the passageway to maintain it open. Althou~h conventional zigzag stents l~ave proven quite useflll in m~ny situations, ~hei ~
per~ormance c:llarac~eristic.~ tend to decrease as the length ~f the s~ellt incr:eases.
Self-expandincJ stents are norlllally e~aluated with res~ect;
to four pel~or(llallce c~laracleristic.s: the ra~lially o-lt~a1d exE~an.sile force that t}le stellt exerts 011 the vascular wall;
t~le small dialneter ~o which tl~e .stent is c~pable of beiny conlpressed for the insert:iol- proceduLe; ~he ability of tlle sl:ent to ad~pt to cnrved p assa~eways in the patiellt: ~ s bocly; -I and ttle stabi1ity of the stcnt in not migral.irl~ Lroln its oricJillal-ly iln~ nted position withirl tlle ~atiellt.
Collvellt.iorlal ~ J st:~nts must no~lnally l)e macle W093/13825 PCT/US93/00355 ~ ~
2 1 ~ 5 ~ ' -2-relatively short be~ause Llle straigllt wire sections E-revent tlle stent fron~ readily adapting to curves in the passageway ~of a patient. FurtllernloLe, tlle expansile f~rce of converltional zigzag stents generally decreases witll tlle lenyth of tlle stellt. One solu~ion to these drawbacks }las been to modify the conventional zigzag stent by connecting a plurality of shorter s~ents end on en~ to create one lonyer zi~za~ stent assembly. Alt~lough these modifie~ zigzag stents represent an improvement over conventiollal ziyzag stents for certain applications, there exists a need for an elongated self-exparlding stent that irlcludes the advantages oE bo~l conventional and modified zigzag sten~s but wllictl has improved performance charact-elistics over bo~h.
The preser~t invelltion als~ represents an improvemer~t over t~le self-expandillg spiral stents described in U.S. Patent No. ~-5,019,090 to Pincl~ulc. Pinchuk teaches the production of an elongated zigzag pattern by spirally wrappin~ a wire about an oblong mandrel, removin~ the mandrel, and then ~lattenirlg the spiral to produce an elorlgated zigzag band. The elongated zigzag ~a~ld is then spirally wrapped around a c~lindrical mandrel to p~oduce the stent. One drawback to t}le Pinchuk design, however, is that all of tlle elongate melllbers that nlake up the zigzag pattern have equal lengths. I'he resul~
being that a bisector of tlle angle defined by each pair of elongated members is not parallel to the central axi~ of the finislled stent. This causes the sten~ t.o undesirab]y ~ist~rt in shape wl~en radially compre.ssed for tl~e implantati~n procedllr~. What is needed is a spiral zigzag stent in wllicl i a bisector of each pair of elon~ate~ mem~ers is pa~allel to the central axis of t~e fillislled stent. 5ucll a stent cannot be produced by the method for making stents taugllt by E'in~hl~k.
WO9~/l382s PCT/US93/003~5 SUMMARY OF l~E INVENTION
The preferred enlbodimerlt ~ tlle ~resent invelltic~n includes a wire bent illtO arl elongated zigzag yatteln ~laviny a ~ rality of substantially ~traight wire sections separatillg a ~:lurality of bends. Tlle eloncJated ziyzag pattern is ~lelically WOUII~ abollt a central axis to define a tubular shape such that a majority oE the plurality of-ben~s are disposed in a helix. Means are provided for interconnecting adjacent bends of the helix. T)le stent has the capability of beillg Ladially compressed into a Slllall-diameter Sllape such that the straigl~t wire sections atld the bends are tiglltly packed aroulld the central axis of the tubular shape. T~le stent will resiliently self expand to assulne t~le tubular shape when released from tt~e c~mpressed state.
One o~ject of the present invention is to provide an elongated self-expanding stent having substantially uniform expansile force along the length of tlle stent.
Another object of the present invention is to provi~e a self-expanding stent which may be compressed into a small dialneter for improved percutaneous insertability.
Still another object of the present invention is to ~rovi~le an elongated self-ex~ndin~ stent W~liCh has a substantially uniform capability along its length to adapt to curves in tlle vascular system where the stent is implanted.
Another object of the present invention is to provide a ~ent wllich ~las improved .s-ability in mailltainil~y its position within tlle ~)a~ient.
Final~y, it is an object ~ t~le present invention to provide an improved self-expanding stent.
Related o~jects alld advantages of t~le present inverltio wi]l ~e appare~lt from the following descripti~
WO93~13825 PCT/US93/00355 ~ BRIEF DESCRIPTION OF THE DRAWINGS ;
FIG. l is a plan view showing a wire bent into an elongated zigzag pattern.
- FIG. 2 is an enlarged view of one end of the zigzag pattern of FIG. l.
FIG. 3 is a side elevation of the preferred embodiment of the present invention in its expanded state.
FIG. 4 is an end view of the stent of FIG. 3.
FIG. 5 is a side elevation of the prefexred embodiment of the present invention in its compressed state.
FIG. 6 is an enlarged view of a portion stent of FIG. 3.
FIG. 7 is a side elevation of another embodiment of the present invention in its e~panded shape.
.: ~
:
WO 93/13825 PCI'/US93/003~5 21~7~i5~
~ 'SCRI PTION O~ T~ ' P~EIi'ERREI) EMBOl~M~N'r For the purposes of promotiny an un~lerstan~ 9 o~ tlle principles of the inver~l:ion, leferenLe will now be made to - tlle embodiment illustrated ill the drawir1gs and specific 5 language will be used t:o de~cribe t;~1e salne. It will nevertheless be ur1ders1;oo(~ t~la~: no limit:atio11 of tt1e scope of the invention is t~lereby intended such alterations and fllrther modi~icatiolls in the illustrated device and such further ap~lications of the principles of the invention as illustrated therein beillg contemplated as would rlorlnally occur to one skilled in the a~ to which ~le invellLion relates.
Referriny now more particularly to the ~rawings there i.s illustrated in FIG. 1 a midpoint in the construction of the stent which comprises the preferred embodiment of the present inverltion. FIG. 1 shows a wire berlt into an elongated ziyzag pattern 5 having a plurality of substantially straight wire sections 9-15 of various lengths sepaeated ~)y a pl~Jrality oE
bends 8. The wire has first and secorld ends designated as 6 ~:
and 7 respectively. Zigzay pattern S is prefera~ly formed from a single strand of staillless steel wire having a diameter in ~he ran~e of 0.005 to 0.025 inrh.
El~. 3 silows a complete~ stent 30 ae~cordiny to tl~e preferred embodimerlt of the ~resent invention. The construction of the sten~ is completed by ~lelically winding elongated zigzag pattern 5 abou~ a central axis 31. Zigzag ~' pattern 5 is wound in such a wa~ that a majority of the bend-;
8 are distribllted in a helix alol~9 tlle lerlgt}l of l.~le slent 30. Theré are preferably about twelve iJIterconnecte~ bends : 30 in each revolution of the llelix or six adjacerlt bellds o~ the zi~zag pa~tern in eacll rev~lutioll. lhe ~onstru~tion v~ stent 30 is completed by intercorlnectiJIg adjacent berlds of the helix with a filament 32, prefera~ly ~ nylon Inonofilanlerlt suture. FiJ.ament 32 acl-s as a limit mealls to prev~nt tlle WO 93/13825 PCr/US93/00355 ~ .
2 1 2 7 ~
stent from ful~ther radial exparlsion l)eyond the tuL)ular shaE)e shown in Fiys. 3 a~ld 4 . ~l~he t:ul~ular shape has a centl al axis 31, a firsl: end 33 anr~ a sec~?nc~ end 35. Each end of s~erlt 30 is defined by a plu~ality of elld bends 36, ~1hicll are 5 themse1ves interconnected with a filarllerlt 34. Vtllel:
enll:)odimerlts of tl~e pre~ent inventior) ~re contel~ l ate~
which the end bends 36 are 1eft; uncollrl~cted in t~le ~inislle~l :
stent. FIG. 4 shows an end view o~ stent 30 further revealing its tubular shape. FIG. 5 shows stent 30 of FlG. 3 when radially compressed about central axis 31 such that t~e straight wire sections and tlle bends are tiglltly packed arollnd central axis 31.
Referring back to FIG. 1, the zigzag pattern is Inade IIE~
of straight wire sections having various lengths which are distributed in a certain pattern to ~etter facilitate the helical structure of tle ~inal stent construction. For ~-instance, in one embodiment, end wire sections 9 col-ld be made to a length of 9 Inm followed by two wil:e sections 11 each being 11 nun in length. Wire sections 11 are followed by two 13 mm wire sections 13, which are in turn followed by two wire sections 15 having a length of 15 mm. Sections 15 are followed by a single wire section 17 having a length of 17 mm. These gradually increasing wire sections at eit~ler end o~ the zigzag pattern enable the fillal ~tent to h~ve well , 25 defined squale ends. Jn other words, the gradually increasing length wire sections on either end of the zi4zag pattern enable the final stent to have a tubular shape in W}liCh tlle ends df the tube are substarltially per~enclicular to the central axis of the stent. Following wire secti-~n 17, there are a plurality of alternating length secl.ions 13 an 15. Short sections 13 being 13 n~m in length and long sections 15 being 15 n~ in length. This alternating sequence is continued for whatever distance is desired to correspond to the desired length of the Ein~l stent. The difference in length between tlle sho~t sections 13 and long sections 15 is WO93/13825 PCT/VS93/0~355 2 127~8 prilllarily depen~e~lt up~n ~he desired slo~e oE tlle ll~lix (see J~ in FIG. ~) and t~le ~esire~ llum~er ~ bends in eacl ~revolu~ioll of the }lelix.
Anottler inlportant aspe~t of tlle Lresent inventivrl is illllstrat~d in FIG. fi, wllich i~ a~l enlarged ~iew oE ~ portion of the stent shown in FIG. 3. The body of stellt 30 inclu~es a series of alternating sholt an~ lony ~eo~tio~ls, 13 and 15 respectively. A bend 8 connects eac~l pair of sllort and lolig sections 13 and 15. Eacll belld 8 defilles an al)gle 2~ which can be ~isected by a ~isector ~0. These sholt and l~ng sections are arranged in such ~ way that bisector 40 is parallel to tlle central axis 31 of the sterlt. This allows the stent to ~e ra~;ally compressed wi~hout unllecessary distortion .
FIG. 2 shows a~l enlaLged view ~f ol-e en~ of tl~e zigzag pattern. End 6 of the wiee i5 bent to form a closed eye portion 20. Eye 20 is preferal)ly kept c~osed t~y the application of the slnall anlount of solder to t~le end 6 of the wire after it has been bent into a small loop. Each of the bends 8 of the zigzag pattern are bent to inclu(le a small eye portion designated as 21 and 23 in FIG. 2, respectively. Eye 21 includes a small amount of solder 22 which renders eye 21 closed. Eye 23 includes no s~lder and is left open. In ~lle preEerred embodin~ellt, all the end ben~s ~6 sllown in E'IG. 3 ,25 are formed and soldered sinlilar to closed eye 21 so that the filalnent which is tied to each eye is less like]y to cscape.
The ~ends 8 wlliCIl define t}le helix call h~ either in the rol~n of a ~losed eye, as in eye 21, or open as in eye 23.
! I ~IG.~ 7 shows arlotller enlbodillle)lt of the preserlt illvel~tion. Sterlt 50 is similar to stent 30 ~iscus~e previously except in this case, end bends 5~ are not intercoJlnected to one an~ther. Stellt 50 is also diffeIellt in the way that ttle respective ends or tlle wire are conl-ecte~ to tbe remainder of the ster~t. In the case oE stent 50, the end sectiolls 5~ are sol~ered to arl adjaceJIt elongate~ sectio WO93/1~25 PCT/US93/00355 60. ~1l the otller halld, e~ds 6 of stellt 3U showl~ F]~. 3 are tied il'ltO t~le helix between two adjacellt ~en~s 8 of the helix. It is to ~e urlderstood that ~he means em~loyed for connec~ing tlle ends o~ tlle wire into the ~ir)ished stent ca be varied without depalti~ from ttle intellde~ sco~e ~E tlle present inventioJl. What is im~ortarlt is that t~le e~
sections of the wire be secured to tlle stent ill sucll a w~y that they are not left to dangle freely so as ~o illterfere with the stents expansion or present a risk oE unnecessary -trauma to the vascular wall of the paLient.
Because of the l~elical pattern of the present inve2ltion, t}le bends of the stent are distribllted along its lellgth rather than being concentrate~ at certai-l locatiolls alorlg the lellgtll of the stent. Thus th~ spiral stellt is able to defille a smaller compressed shape than either conve~ltional zi~zag stents or modified zigzag stents in whicll the bends are all located at a single location along t~le length of the stent.
It is also believ~d that ~lle helical pattern allows the elongated stent to more uniformly accommodate cllrves in the vascular system of a ~atient. T~e helical structllre also produces a more ulliform radial expansile force along the length of the stent. E'inally, the spiral stents o~ tlle present invention are more relia~le in mail~tainin~ eir pOSitiOII within a patierlt.
One variation of t~le presellt inven~iorl migllt illclllde a fle~ible sleeve attaclled to t~le outer or inner surface of t~le ~.
stent sucll that an elonyated stent could be used to Lepair a~
aneurysm. ln this use, the end portions o~ the sleeved stent I wollld contact the wall u~ t~e vefisel, and the body o~ the sleeved s~ent would span the alleurysnl. l'he sleeve could be made from nylon, plastic or any otller biocoml~atible material. If the sleeve were n~ade o~ ~astic, the s~en~
cvuld be attached to t~le sleeve by ell~beddiny the stent in tlle plasl;ic. If made of nylo~ he sleeve could be attached l:o 35 the sterlt by a plurali~y of stitches. It lS to be understo~d wo93J13x2s PCT/US93/00355 7 127~ ~8 tllat ~lle Illeans for attachillg ~l~e sten~ to ~lle sleeve ~oul~ be varied deperlding upon ~he sleéve nlaterial, ~nd other factors, without diverging from the intellded scope of the present invention. Furtherll~o~e, tlle sleeve itself could be used as the nlearls for intercon-lec~:ing adjacell~ bends of the helix.
Ano~her variation of the ~)resel~t illvention corlterllplates varyil~g tlle leny~hs of ~lle wi1e sectio~ls ill tlle zi~3zag pattern. Eor installce, shortening the lon~est ~ection and lengthening the shortest sections could be employed to even out the forces near the ends of the stent as well as ~o make square ends. Another variation would be to arrange the zigzag pattern in such a way that t~e tubular s~lape defined by the s~ellt has a dianleter that varies alol~y the lenytll o~
the stent. In other words, a stent could be made hour-glass in sha~e, or have a steadily tapered inner diameter, or even a combination of the two. This could 1)e accomplished by varying along the lenq~h o~ tlle stellt the nuln~er oE bends in each revolution of the helix. In these variations, the l-elical pattern would be maintained but would ~e irreyularly shaped along the len~th o~ the stent. Still another variation would be to vary the lenqths of the wire sections within the body oE the stent tv create curves or to vary the expansile force along the lengttl of the stent.
While the invention has been illus~rated alld descri~ed in detail in the drawings and foregoing descriptioll, tll~ same is to be considered as illustrative and n~t restrictive in character, it being understood that only the preferred embodiment has been showrl and described and t~lat al1 ch~ncles I and modifications tl~at conle withil~ the spirit of the inventicm are clesired to be protected.
, . . .
The preser~t invelltion als~ represents an improvemer~t over t~le self-expandillg spiral stents described in U.S. Patent No. ~-5,019,090 to Pincl~ulc. Pinchuk teaches the production of an elongated zigzag pattern by spirally wrappin~ a wire about an oblong mandrel, removin~ the mandrel, and then ~lattenirlg the spiral to produce an elorlgated zigzag band. The elongated zigzag ~a~ld is then spirally wrapped around a c~lindrical mandrel to p~oduce the stent. One drawback to t}le Pinchuk design, however, is that all of tlle elongate melllbers that nlake up the zigzag pattern have equal lengths. I'he resul~
being that a bisector of tlle angle defined by each pair of elongated members is not parallel to the central axi~ of the finislled stent. This causes the sten~ t.o undesirab]y ~ist~rt in shape wl~en radially compre.ssed for tl~e implantati~n procedllr~. What is needed is a spiral zigzag stent in wllicl i a bisector of each pair of elon~ate~ mem~ers is pa~allel to the central axis of t~e fillislled stent. 5ucll a stent cannot be produced by the method for making stents taugllt by E'in~hl~k.
WO9~/l382s PCT/US93/003~5 SUMMARY OF l~E INVENTION
The preferred enlbodimerlt ~ tlle ~resent invelltic~n includes a wire bent illtO arl elongated zigzag yatteln ~laviny a ~ rality of substantially ~traight wire sections separatillg a ~:lurality of bends. Tlle eloncJated ziyzag pattern is ~lelically WOUII~ abollt a central axis to define a tubular shape such that a majority oE the plurality of-ben~s are disposed in a helix. Means are provided for interconnecting adjacent bends of the helix. T)le stent has the capability of beillg Ladially compressed into a Slllall-diameter Sllape such that the straigl~t wire sections atld the bends are tiglltly packed aroulld the central axis of the tubular shape. T~le stent will resiliently self expand to assulne t~le tubular shape when released from tt~e c~mpressed state.
One o~ject of the present invention is to provide an elongated self-expanding stent having substantially uniform expansile force along the length of tlle stent.
Another object of the present invention is to provi~e a self-expanding stent which may be compressed into a small dialneter for improved percutaneous insertability.
Still another object of the present invention is to ~rovi~le an elongated self-ex~ndin~ stent W~liCh has a substantially uniform capability along its length to adapt to curves in tlle vascular system where the stent is implanted.
Another object of the present invention is to provide a ~ent wllich ~las improved .s-ability in mailltainil~y its position within tlle ~)a~ient.
Final~y, it is an object ~ t~le present invention to provide an improved self-expanding stent.
Related o~jects alld advantages of t~le present inverltio wi]l ~e appare~lt from the following descripti~
WO93~13825 PCT/US93/00355 ~ BRIEF DESCRIPTION OF THE DRAWINGS ;
FIG. l is a plan view showing a wire bent into an elongated zigzag pattern.
- FIG. 2 is an enlarged view of one end of the zigzag pattern of FIG. l.
FIG. 3 is a side elevation of the preferred embodiment of the present invention in its expanded state.
FIG. 4 is an end view of the stent of FIG. 3.
FIG. 5 is a side elevation of the prefexred embodiment of the present invention in its compressed state.
FIG. 6 is an enlarged view of a portion stent of FIG. 3.
FIG. 7 is a side elevation of another embodiment of the present invention in its e~panded shape.
.: ~
:
WO 93/13825 PCI'/US93/003~5 21~7~i5~
~ 'SCRI PTION O~ T~ ' P~EIi'ERREI) EMBOl~M~N'r For the purposes of promotiny an un~lerstan~ 9 o~ tlle principles of the inver~l:ion, leferenLe will now be made to - tlle embodiment illustrated ill the drawir1gs and specific 5 language will be used t:o de~cribe t;~1e salne. It will nevertheless be ur1ders1;oo(~ t~la~: no limit:atio11 of tt1e scope of the invention is t~lereby intended such alterations and fllrther modi~icatiolls in the illustrated device and such further ap~lications of the principles of the invention as illustrated therein beillg contemplated as would rlorlnally occur to one skilled in the a~ to which ~le invellLion relates.
Referriny now more particularly to the ~rawings there i.s illustrated in FIG. 1 a midpoint in the construction of the stent which comprises the preferred embodiment of the present inverltion. FIG. 1 shows a wire berlt into an elongated ziyzag pattern 5 having a plurality of substantially straight wire sections 9-15 of various lengths sepaeated ~)y a pl~Jrality oE
bends 8. The wire has first and secorld ends designated as 6 ~:
and 7 respectively. Zigzay pattern S is prefera~ly formed from a single strand of staillless steel wire having a diameter in ~he ran~e of 0.005 to 0.025 inrh.
El~. 3 silows a complete~ stent 30 ae~cordiny to tl~e preferred embodimerlt of the ~resent invention. The construction of the sten~ is completed by ~lelically winding elongated zigzag pattern 5 abou~ a central axis 31. Zigzag ~' pattern 5 is wound in such a wa~ that a majority of the bend-;
8 are distribllted in a helix alol~9 tlle lerlgt}l of l.~le slent 30. Theré are preferably about twelve iJIterconnecte~ bends : 30 in each revolution of the llelix or six adjacerlt bellds o~ the zi~zag pa~tern in eacll rev~lutioll. lhe ~onstru~tion v~ stent 30 is completed by intercorlnectiJIg adjacent berlds of the helix with a filament 32, prefera~ly ~ nylon Inonofilanlerlt suture. FiJ.ament 32 acl-s as a limit mealls to prev~nt tlle WO 93/13825 PCr/US93/00355 ~ .
2 1 2 7 ~
stent from ful~ther radial exparlsion l)eyond the tuL)ular shaE)e shown in Fiys. 3 a~ld 4 . ~l~he t:ul~ular shape has a centl al axis 31, a firsl: end 33 anr~ a sec~?nc~ end 35. Each end of s~erlt 30 is defined by a plu~ality of elld bends 36, ~1hicll are 5 themse1ves interconnected with a filarllerlt 34. Vtllel:
enll:)odimerlts of tl~e pre~ent inventior) ~re contel~ l ate~
which the end bends 36 are 1eft; uncollrl~cted in t~le ~inislle~l :
stent. FIG. 4 shows an end view o~ stent 30 further revealing its tubular shape. FIG. 5 shows stent 30 of FlG. 3 when radially compressed about central axis 31 such that t~e straight wire sections and tlle bends are tiglltly packed arollnd central axis 31.
Referring back to FIG. 1, the zigzag pattern is Inade IIE~
of straight wire sections having various lengths which are distributed in a certain pattern to ~etter facilitate the helical structure of tle ~inal stent construction. For ~-instance, in one embodiment, end wire sections 9 col-ld be made to a length of 9 Inm followed by two wil:e sections 11 each being 11 nun in length. Wire sections 11 are followed by two 13 mm wire sections 13, which are in turn followed by two wire sections 15 having a length of 15 mm. Sections 15 are followed by a single wire section 17 having a length of 17 mm. These gradually increasing wire sections at eit~ler end o~ the zigzag pattern enable the fillal ~tent to h~ve well , 25 defined squale ends. Jn other words, the gradually increasing length wire sections on either end of the zi4zag pattern enable the final stent to have a tubular shape in W}liCh tlle ends df the tube are substarltially per~enclicular to the central axis of the stent. Following wire secti-~n 17, there are a plurality of alternating length secl.ions 13 an 15. Short sections 13 being 13 n~m in length and long sections 15 being 15 n~ in length. This alternating sequence is continued for whatever distance is desired to correspond to the desired length of the Ein~l stent. The difference in length between tlle sho~t sections 13 and long sections 15 is WO93/13825 PCT/VS93/0~355 2 127~8 prilllarily depen~e~lt up~n ~he desired slo~e oE tlle ll~lix (see J~ in FIG. ~) and t~le ~esire~ llum~er ~ bends in eacl ~revolu~ioll of the }lelix.
Anottler inlportant aspe~t of tlle Lresent inventivrl is illllstrat~d in FIG. fi, wllich i~ a~l enlarged ~iew oE ~ portion of the stent shown in FIG. 3. The body of stellt 30 inclu~es a series of alternating sholt an~ lony ~eo~tio~ls, 13 and 15 respectively. A bend 8 connects eac~l pair of sllort and lolig sections 13 and 15. Eacll belld 8 defilles an al)gle 2~ which can be ~isected by a ~isector ~0. These sholt and l~ng sections are arranged in such ~ way that bisector 40 is parallel to tlle central axis 31 of the sterlt. This allows the stent to ~e ra~;ally compressed wi~hout unllecessary distortion .
FIG. 2 shows a~l enlaLged view ~f ol-e en~ of tl~e zigzag pattern. End 6 of the wiee i5 bent to form a closed eye portion 20. Eye 20 is preferal)ly kept c~osed t~y the application of the slnall anlount of solder to t~le end 6 of the wire after it has been bent into a small loop. Each of the bends 8 of the zigzag pattern are bent to inclu(le a small eye portion designated as 21 and 23 in FIG. 2, respectively. Eye 21 includes a small amount of solder 22 which renders eye 21 closed. Eye 23 includes no s~lder and is left open. In ~lle preEerred embodin~ellt, all the end ben~s ~6 sllown in E'IG. 3 ,25 are formed and soldered sinlilar to closed eye 21 so that the filalnent which is tied to each eye is less like]y to cscape.
The ~ends 8 wlliCIl define t}le helix call h~ either in the rol~n of a ~losed eye, as in eye 21, or open as in eye 23.
! I ~IG.~ 7 shows arlotller enlbodillle)lt of the preserlt illvel~tion. Sterlt 50 is similar to stent 30 ~iscus~e previously except in this case, end bends 5~ are not intercoJlnected to one an~ther. Stellt 50 is also diffeIellt in the way that ttle respective ends or tlle wire are conl-ecte~ to tbe remainder of the ster~t. In the case oE stent 50, the end sectiolls 5~ are sol~ered to arl adjaceJIt elongate~ sectio WO93/1~25 PCT/US93/00355 60. ~1l the otller halld, e~ds 6 of stellt 3U showl~ F]~. 3 are tied il'ltO t~le helix between two adjacellt ~en~s 8 of the helix. It is to ~e urlderstood that ~he means em~loyed for connec~ing tlle ends o~ tlle wire into the ~ir)ished stent ca be varied without depalti~ from ttle intellde~ sco~e ~E tlle present inventioJl. What is im~ortarlt is that t~le e~
sections of the wire be secured to tlle stent ill sucll a w~y that they are not left to dangle freely so as ~o illterfere with the stents expansion or present a risk oE unnecessary -trauma to the vascular wall of the paLient.
Because of the l~elical pattern of the present inve2ltion, t}le bends of the stent are distribllted along its lellgth rather than being concentrate~ at certai-l locatiolls alorlg the lellgtll of the stent. Thus th~ spiral stellt is able to defille a smaller compressed shape than either conve~ltional zi~zag stents or modified zigzag stents in whicll the bends are all located at a single location along t~le length of the stent.
It is also believ~d that ~lle helical pattern allows the elongated stent to more uniformly accommodate cllrves in the vascular system of a ~atient. T~e helical structllre also produces a more ulliform radial expansile force along the length of the stent. E'inally, the spiral stents o~ tlle present invention are more relia~le in mail~tainin~ eir pOSitiOII within a patierlt.
One variation of t~le presellt inven~iorl migllt illclllde a fle~ible sleeve attaclled to t~le outer or inner surface of t~le ~.
stent sucll that an elonyated stent could be used to Lepair a~
aneurysm. ln this use, the end portions o~ the sleeved stent I wollld contact the wall u~ t~e vefisel, and the body o~ the sleeved s~ent would span the alleurysnl. l'he sleeve could be made from nylon, plastic or any otller biocoml~atible material. If the sleeve were n~ade o~ ~astic, the s~en~
cvuld be attached to t~le sleeve by ell~beddiny the stent in tlle plasl;ic. If made of nylo~ he sleeve could be attached l:o 35 the sterlt by a plurali~y of stitches. It lS to be understo~d wo93J13x2s PCT/US93/00355 7 127~ ~8 tllat ~lle Illeans for attachillg ~l~e sten~ to ~lle sleeve ~oul~ be varied deperlding upon ~he sleéve nlaterial, ~nd other factors, without diverging from the intellded scope of the present invention. Furtherll~o~e, tlle sleeve itself could be used as the nlearls for intercon-lec~:ing adjacell~ bends of the helix.
Ano~her variation of the ~)resel~t illvention corlterllplates varyil~g tlle leny~hs of ~lle wi1e sectio~ls ill tlle zi~3zag pattern. Eor installce, shortening the lon~est ~ection and lengthening the shortest sections could be employed to even out the forces near the ends of the stent as well as ~o make square ends. Another variation would be to arrange the zigzag pattern in such a way that t~e tubular s~lape defined by the s~ellt has a dianleter that varies alol~y the lenytll o~
the stent. In other words, a stent could be made hour-glass in sha~e, or have a steadily tapered inner diameter, or even a combination of the two. This could 1)e accomplished by varying along the lenq~h o~ tlle stellt the nuln~er oE bends in each revolution of the helix. In these variations, the l-elical pattern would be maintained but would ~e irreyularly shaped along the len~th o~ the stent. Still another variation would be to vary the lenqths of the wire sections within the body oE the stent tv create curves or to vary the expansile force along the lengttl of the stent.
While the invention has been illus~rated alld descri~ed in detail in the drawings and foregoing descriptioll, tll~ same is to be considered as illustrative and n~t restrictive in character, it being understood that only the preferred embodiment has been showrl and described and t~lat al1 ch~ncles I and modifications tl~at conle withil~ the spirit of the inventicm are clesired to be protected.
, . . .
Claims (10)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A self-expanding stent comprising:
a wire bent into an elongated zigzag pattern having a plurality of substantially straight wire sections separating a plurality of bends; said zigzag pattern being helically wound about a central axis to define a tubular shape such that a majority of said plurality of bends are disposed in a helix;
means for interconnecting adjacent bends of said helix;
and said stent having a first configuration of reduced diameter such that said straight wire sections and said bends are tightly packed around said central axis, and said stent being self-expandable to assume a second configuration having an enlarged diameter.
a wire bent into an elongated zigzag pattern having a plurality of substantially straight wire sections separating a plurality of bends; said zigzag pattern being helically wound about a central axis to define a tubular shape such that a majority of said plurality of bends are disposed in a helix;
means for interconnecting adjacent bends of said helix;
and said stent having a first configuration of reduced diameter such that said straight wire sections and said bends are tightly packed around said central axis, and said stent being self-expandable to assume a second configuration having an enlarged diameter.
2. The self-expanding stent of claim 1 wherein said means for interconnecting is a filament, said filament preventing said stent from expanding beyond a tubular shape of predetermined size.
3. The self-expanding stent of claim 2 wherein said stent has two ends, each said end being defined by a plurality of end bends, adjacent said end bends being interconnected by a filament.
4. The self-expanding stent of claim 3 wherein each of said plurality of bends is bent to include an eye portion, said filament being tied to each said eye portion.
5. The self-expanding stent of claim 4 wherein at least two of said eye portions are closed.
6. The self-expanding stent of claim 5 wherein said wire has first and second ends each formed into defining a closed eye portion, said first and second ends being disposed in said helix and interconnected to two adjacent said bends in said helix.
7. The self-expanding stent of claim 2 wherein said wire has first and second ends, each being soldered to a different one of said plurality of straight wire sections.
8. The self-expanding stent of claim 1 wherein said tubular shape defines a length and a diameter that varies along said length.
9. The self expanding stent of claim 1 further comprising a flexible sleeve open at both ends and attached to said stent, said flexible sleeve being supported by said stent.
10. The self expanding stent of claim 1 wherein each of said bends disposed in said helix defines angle, and a bisector of each said angle is substantially parallel to said central axis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/821,477 US5507767A (en) | 1992-01-15 | 1992-01-15 | Spiral stent |
US07/821,477 | 1992-01-15 |
Publications (2)
Publication Number | Publication Date |
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CA2127458A1 CA2127458A1 (en) | 1993-07-22 |
CA2127458C true CA2127458C (en) | 1997-12-02 |
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ID=25233507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002127458A Expired - Lifetime CA2127458C (en) | 1992-01-15 | 1993-01-14 | Spiral stent |
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US (2) | US5507767A (en) |
EP (1) | EP0621792B1 (en) |
JP (1) | JP2691074B2 (en) |
KR (1) | KR0153031B1 (en) |
AT (1) | ATE192662T1 (en) |
AU (1) | AU669153B2 (en) |
CA (1) | CA2127458C (en) |
DE (1) | DE69328616T2 (en) |
ES (1) | ES2147750T3 (en) |
WO (1) | WO1993013825A1 (en) |
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WO1993013825A1 (en) | 1993-07-22 |
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