CA2116115A1 - Sustained-release matrices for dental application - Google Patents

Sustained-release matrices for dental application

Info

Publication number
CA2116115A1
CA2116115A1 CA 2116115 CA2116115A CA2116115A1 CA 2116115 A1 CA2116115 A1 CA 2116115A1 CA 2116115 CA2116115 CA 2116115 CA 2116115 A CA2116115 A CA 2116115A CA 2116115 A1 CA2116115 A1 CA 2116115A1
Authority
CA
Canada
Prior art keywords
sustained
dental application
release matrices
water
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2116115
Other languages
French (fr)
Other versions
CA2116115C (en
Inventor
Mingchih M. Tseng
Carl M. Philbrook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gillette Co LLC
Original Assignee
Mingchih M. Tseng
Carl M. Philbrook
Gillette Canada Inc.
The Gillette Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/898,471 external-priority patent/US5340581A/en
Application filed by Mingchih M. Tseng, Carl M. Philbrook, Gillette Canada Inc., The Gillette Company filed Critical Mingchih M. Tseng
Publication of CA2116115A1 publication Critical patent/CA2116115A1/en
Application granted granted Critical
Publication of CA2116115C publication Critical patent/CA2116115C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B11/00—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B15/00—Other brushes; Brushes with additional arrangements
    • A46B15/0002—Arrangements for enhancing monitoring or controlling the brushing process
    • A46B15/0004—Arrangements for enhancing monitoring or controlling the brushing process with a controlling means
    • A46B15/001—Arrangements for enhancing monitoring or controlling the brushing process with a controlling means with means indicating the remaining useful life of brush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8135—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid or of a haloformic acid; Compositions of derivatives of such polymers, e.g. vinyl esters (polyvinylacetate)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42—Colour properties
    • A61K2800/43—Pigments; Dyes

Abstract

A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices include a water-soluble polymer and a water-insoluble support resin.
CA002116115A 1991-08-23 1992-08-13 Sustained-release matrices for dental application Expired - Fee Related CA2116115C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US74913791A 1991-08-23 1991-08-23
US749,137 1991-08-23
US07/898,471 US5340581A (en) 1991-08-23 1992-06-15 Sustained-release matrices for dental application
US898,471 1992-06-15
PCT/US1992/006770 WO1993003649A1 (en) 1991-08-23 1992-08-13 Sustained-release martrices for dental application

Publications (2)

Publication Number Publication Date
CA2116115A1 true CA2116115A1 (en) 1993-03-04
CA2116115C CA2116115C (en) 2000-05-16

Family

ID=27115063

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002116115A Expired - Fee Related CA2116115C (en) 1991-08-23 1992-08-13 Sustained-release matrices for dental application

Country Status (14)

Country Link
US (3) US5851551A (en)
EP (1) EP0600004B1 (en)
JP (2) JPH06509955A (en)
KR (1) KR100257842B1 (en)
CN (1) CN1055827C (en)
AT (1) ATE173893T1 (en)
AU (1) AU667681B2 (en)
BR (1) BR9206408A (en)
CA (1) CA2116115C (en)
DE (2) DE9219148U1 (en)
DK (1) DK0600004T3 (en)
ES (1) ES2124739T3 (en)
MX (1) MX9204878A (en)
WO (1) WO1993003649A1 (en)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100257842B1 (en) 1991-08-23 2000-06-01 질 시이 리차아드슨 Substained-release martrices
AU704007B2 (en) * 1991-09-13 1999-04-01 Gillette Canada Inc. Toothbrushes
US6594904B1 (en) * 1994-07-01 2003-07-22 The Gillette Company Shaving system
US6295733B1 (en) 1994-08-03 2001-10-02 Warner-Lambert Company Changeable color shaving aid
DE19646519A1 (en) * 1996-11-12 1998-05-14 Pedex & Co Gmbh Dental care device and method for manufacturing cleaning elements for dental care devices
US20020018754A1 (en) * 1999-03-15 2002-02-14 Paul Albert Sagel Shapes for tooth whitening strips
US6136297A (en) * 1997-06-06 2000-10-24 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
US6582708B1 (en) 2000-06-28 2003-06-24 The Procter & Gamble Company Tooth whitening substance
US6096328A (en) * 1997-06-06 2000-08-01 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
EP1023036B1 (en) * 1997-10-18 2002-01-09 DDG Dental Devices GmbH Disinfecting agent
CA2344697C (en) * 1998-09-24 2012-11-13 Advantage Dental Products, Inc. Calcified tissue facing preparation containing an antimicrobial agent
US6726899B2 (en) 1998-09-24 2004-04-27 Advantage Dental Products, Inc. Calcified tissue facing preparation containing antimicrobial agent
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US6381795B1 (en) * 1998-11-02 2002-05-07 Raimund Hofmann Brush part for electrical toothbrush
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
AU768471B2 (en) 1999-07-02 2003-12-11 Procter & Gamble Company, The Delivery system for oral care compositions comprising organosiloxane reins using a removable backing strip
EP1255640B1 (en) 1999-12-28 2008-05-21 Kimberly-Clark Worldwide, Inc. Controlled release anti-microbial wipe for hard surfaces
MXPA02006182A (en) 1999-12-28 2002-12-05 Kimberly Clark Co Usedependent indicator system for absorbent articles.
DE10010572A1 (en) * 2000-03-03 2001-09-06 Coronet Werke Gmbh Thermoplastic (e.g. tooth) brush has regions containing surface-diffusing (especially silver) antimicrobial substance and regions guaranteeing required bending and recovery properties
IL135061A0 (en) * 2000-03-14 2001-05-20 Ahron Jodaikin Strategic targeted fluoridation and chemical treatment of teeth
US20050175959A1 (en) * 2000-03-14 2005-08-11 Coll Partners Ltd. System for the controlled delivery of an active material to a dental site
US8652446B2 (en) 2000-03-17 2014-02-18 Lg Household & Healthcare Ltd. Apparatus and method for whitening teeth
US7785572B2 (en) 2000-03-17 2010-08-31 Lg Household And Health Care Ltd. Method and device for teeth whitening using a dry type adhesive
CA2402021C (en) 2000-03-17 2005-04-12 Lg Household & Health Care Ltd. Patches for teeth whitening
US6689344B2 (en) 2000-03-17 2004-02-10 Lg Household & Healthcare Ltd. Patches for teeth whitening
US6582717B1 (en) * 2000-04-07 2003-06-24 Massachusetts Institute Of Technology Drug delivery composition and device
DE10017306A1 (en) 2000-04-09 2001-10-11 Pedex & Co Gmbh Process for the production of bristles for the application of media
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
DE10024223A1 (en) * 2000-05-17 2001-11-22 J E Faller Gmbh Buerstenfabrik Brush has individual bristles or bunches of bristles in mounting, whose surface is sealed around their bases
US6228355B1 (en) * 2000-06-13 2001-05-08 The United States Of America As Represented By The Secretary Of Agriculture System for the control of enteropathogenic bacteria in the crops of poultry
PL360092A1 (en) * 2000-06-28 2004-09-06 The Procter & Gamble Company Structures and compositions increasing the stability of peroxide actives
CA2419727A1 (en) 2000-08-23 2002-02-28 Ira D. Hill Physical improvements in coated monofilament dental tapes
AU8668501A (en) 2000-08-23 2002-03-04 Ira D Hill Monofilament dental tapes with substantive coatings
US6887493B2 (en) * 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
US6565873B1 (en) * 2000-10-25 2003-05-20 Salvona Llc Biodegradable bioadhesive controlled release system of nano-particles for oral care products
US6589562B1 (en) 2000-10-25 2003-07-08 Salvona L.L.C. Multicomponent biodegradable bioadhesive controlled release system for oral care products
CA2434419A1 (en) * 2001-01-22 2002-08-01 Michael Schweigert Coated monofilament tape bobbins and methods for winding
EP1359862A1 (en) 2001-01-22 2003-11-12 Dale G. Brown Non-crystalline saliva-soluble coatings for elastomeric monofilament dental tapes
US6591844B2 (en) 2001-01-22 2003-07-15 Peri-Deat Limited Elastomeric monofilament dental tapes
JP3936143B2 (en) * 2001-02-06 2007-06-27 憲司 中村 Antibacterial and deodorant cosmetic brush and method for producing the same
US6419906B1 (en) * 2001-03-12 2002-07-16 Colgate Palmolive Company Strip for whitening tooth surfaces
US6514483B2 (en) * 2001-03-12 2003-02-04 Colgate Palmolive Company Strip for whitening tooth surfaces
US6503486B2 (en) * 2001-03-12 2003-01-07 Colgate Palmolive Company Strip for whitening tooth surfaces
WO2002087388A1 (en) * 2001-04-30 2002-11-07 Klaus Neufeld Container for cleaning implements, in addition to an insertion body, toothbrush and reservoir
US6946142B2 (en) * 2001-06-23 2005-09-20 Lg Household & Healthcare Ltd. Multi-layer patches for teeth whitening
US7017591B2 (en) * 2001-08-23 2006-03-28 International Tape Partners Llc Particulate coated monofilament devices
US6575176B1 (en) 2001-08-23 2003-06-10 International Tape Partners, Llc Monofilament dental tapes with soft abrasive coatings
US20030168077A1 (en) * 2002-02-11 2003-09-11 Brown Dale G. Coated micromesh dental devices overcoated with imbedded particulate
US7025986B2 (en) * 2002-02-11 2006-04-11 International Tape Partners Llc Micromesh interproximal devices
US20060243297A1 (en) * 2005-04-29 2006-11-02 Brown Dale G Coated monofilament oriented HDPE dental tapes
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
BR0309844A (en) * 2002-05-07 2005-02-15 Control Delivery Sys Inc Processes for forming a drug delivery device
US6949240B2 (en) * 2002-05-23 2005-09-27 The Procter & Gamble Company Tooth whitening products
US20030226223A1 (en) * 2002-06-11 2003-12-11 The Procter & Gamble Co. High efficiency electric toothbrush
US6902397B2 (en) * 2002-08-01 2005-06-07 Sunstar Americas, Inc. Enhanced dental hygiene system with direct UVA photoexcitation
JP3962661B2 (en) * 2002-08-30 2007-08-22 三菱重工業株式会社 Electrostatic chuck support mechanism, support base device, and plasma processing apparatus
US20050100515A1 (en) * 2002-09-11 2005-05-12 The Procter & Gamble Company Tooth whitening products
US20050019277A1 (en) * 2002-09-11 2005-01-27 The Procter & Gamble Company Tooth whitening products
US20040120903A1 (en) * 2002-09-11 2004-06-24 The Procter & Gamble Company Tooth whitening strips
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US6916463B2 (en) * 2002-09-24 2005-07-12 The Procter & Gamble Company Oral products having an aesthetic layer
US7934284B2 (en) 2003-02-11 2011-05-03 Braun Gmbh Toothbrushes
US7488757B2 (en) 2003-03-24 2009-02-10 Becton, Dickinson And Company Invisible antimicrobial glove and hand antiseptic
US7273327B2 (en) * 2003-06-20 2007-09-25 Colgate-Palmolive Company Oral care implement
CN1703173B (en) 2003-12-10 2010-04-28 丘奇和德怀特有限公司 Modular electric toothbrushes
AU2014268187B2 (en) * 2004-08-11 2015-10-01 Colgate-Palmolive Company Oral care implement
US8042217B2 (en) 2004-11-02 2011-10-25 Colgate-Palmolive Company Toothbrush and method of making the same
US20060283477A1 (en) * 2005-06-16 2006-12-21 Bryan Oronsky Interdental cleaning article with functional messages
KR100993123B1 (en) * 2005-07-12 2010-11-08 콜게이트-파아므올리브캄파니 Oral care implement having reservoir for dispensing active agent
CN101299944B (en) * 2005-08-26 2010-09-01 高露洁-棕榄公司 Oral care instrument including an oral care liquor
US8092110B2 (en) 2005-08-26 2012-01-10 Colgate-Palmolive Company Oral care instrument including an oral care agent
WO2007039879A1 (en) * 2005-10-04 2007-04-12 Koninklijke Philips Electronics, N.V. Magnetic actuated wear indicator for personal care appliances
JP5801528B2 (en) 2005-12-14 2015-10-28 スリーエム イノベイティブ プロパティズ カンパニー Antibacterial adhesive film
WO2007070649A2 (en) 2005-12-14 2007-06-21 3M Innovative Properties Company Antimicrobial coating system
AU2007200069A1 (en) * 2006-01-06 2007-07-26 Craig Edward Harder Magnetic wear device
US7727516B2 (en) 2006-02-28 2010-06-01 The Procter & Gamble Company Reduction of hair growth
NZ572207A (en) 2006-03-24 2012-02-24 Auxilium Int Holdings Inc Stabilized compositions containing alkaline labile drugs
WO2007112285A2 (en) * 2006-03-24 2007-10-04 Auxilium Pharmaceuticals, Inc. Process for the preparation of a hot-melt extruded laminate
US8932535B2 (en) 2006-03-31 2015-01-13 The Invention Science Fund I, Llc Surveying sterilizer methods and systems
US20070231192A1 (en) 2006-03-31 2007-10-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Sterilization methods and systems
US8277724B2 (en) 2006-03-31 2012-10-02 The Invention Science Fund I, Llc Sterilization methods and systems
US8114342B2 (en) 2006-03-31 2012-02-14 The Invention Science Fund I, Llc Methods and systems for monitoring sterilization status
US8758679B2 (en) 2006-03-31 2014-06-24 The Invention Science Fund I, Llc Surveying sterilizer methods and systems
US11185604B2 (en) 2006-03-31 2021-11-30 Deep Science Llc Methods and systems for monitoring sterilization status
US7638090B2 (en) 2006-03-31 2009-12-29 Searete Llc Surveying sterilizer methods and systems
CN101495085A (en) * 2006-04-07 2009-07-29 宝洁公司 Oral care regimens and kits
US7785299B2 (en) * 2006-05-08 2010-08-31 Becton, Dickinson And Company Vascular access device time sensitive status indication
US8240936B2 (en) * 2007-02-22 2012-08-14 Colgate-Palmolive Company Toothbrush having soft tissue cleaning elements
US7850453B2 (en) * 2007-08-08 2010-12-14 Coll Partners Ltd. Reshapable device for fixation at a dental site
US20090110890A1 (en) * 2007-10-30 2009-04-30 3M Innovative Properties Company Color changing wear indicator
AU2009212331B2 (en) 2008-02-08 2011-12-08 Colgate-Palmolive Company Compositions and devices
US8510893B2 (en) 2008-06-20 2013-08-20 Colgate-Palmolive Company Toothbrush with visual and/or other sensory effects
WO2010114551A1 (en) 2009-04-02 2010-10-07 Colgate-Palmolive Company Color changing consumer products
US8529150B2 (en) 2009-09-23 2013-09-10 Richard Carl Olson Toothbrush device
MX2012006291A (en) * 2009-12-23 2012-07-03 Colgate Palmolive Co Device for identifying oral conditions.
US8734272B2 (en) * 2010-01-21 2014-05-27 Nike, Inc. Golf ball wear indicator
EP2363038A1 (en) * 2010-03-05 2011-09-07 Didar Almabekov Toothbrush
WO2012100244A2 (en) 2011-01-21 2012-07-26 Avery Dennison Corporation Chlorhexidine gluconate containing solvent adhesive
US11058793B2 (en) 2011-05-16 2021-07-13 Avery Dennison Corporation Adhesive containing microparticles
US20130000659A1 (en) * 2011-12-01 2013-01-03 Davis John J Toothbrush/toothpaste fluoride dosing toothbrush, system and method
RU2646502C2 (en) 2012-10-17 2018-03-05 Дзе Проктер Энд Гэмбл Компани Strip for active substance delivery for oral care and methods of active substances delivery for oral care
BR112015019044B1 (en) 2013-02-07 2022-02-08 Avery Dennison Corporation ANTIMICROBIAL ADHESIVE COMPOSITION, ITS MEDICAL ARTICLE, AND METHOD OF INCREASING THE RELEASE OF AN ANTIMICROBIAL AGENT FROM AN ADHESIVE COMPOSITION
EP2968014B1 (en) 2013-03-15 2019-04-24 Avery Dennison Corporation Transparent cover dressing application system and inclusion of label strip
JP5680155B2 (en) * 2013-08-19 2015-03-04 小林製薬株式会社 Covering member
US9668844B2 (en) 2013-11-06 2017-06-06 Colldent Y.A Ltd Device for fixation at a dental site
EP3151813B1 (en) 2014-06-05 2020-12-09 Avery Dennison Corporation Articles with active agent concentrated at the substrate contacting surface and related methods
US10021964B2 (en) 2014-06-13 2018-07-17 L'oreal Replacement indicating brush
JP2015145377A (en) * 2015-03-02 2015-08-13 コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ Color changing consumer product
CN106963662B (en) * 2017-03-15 2020-05-12 广州薇美姿实业有限公司 Color-changing toothpaste for children and preparation method and application thereof
US10736413B2 (en) * 2017-07-31 2020-08-11 L'oreal Systems, devices, and methods of a self-activation use odometer for a skin care brush
US10745540B2 (en) * 2017-08-01 2020-08-18 Carefusion 2200, Inc. Protection and selective release of colorant
US11103057B2 (en) 2017-11-27 2021-08-31 Colgate-Palmolive Company Oral care implement
US10849419B2 (en) 2018-03-08 2020-12-01 Olson Ip Technologies, Inc. Oral care device
CN113056309A (en) 2018-11-27 2021-06-29 高露洁-棕榄公司 Oral care implement with delivery component
US11419462B2 (en) * 2019-03-07 2022-08-23 Gojo Industries, Inc. Wipes dispensing nozzles having wear indicators and wipes dispensers having the same
US11134771B2 (en) 2019-05-06 2021-10-05 L'oreal Skin care brush systems having cleansing agent-infused elements
US11051606B2 (en) 2019-06-28 2021-07-06 Colgate-Palmolive Company Oral care implement and method of assembling the same
US11707130B2 (en) 2019-12-26 2023-07-25 L'oreal Fluid-filled cleaning head
CN115251562A (en) * 2022-08-19 2022-11-01 好来化工(中山)有限公司 Tooth brush

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE21197E (en) * 1939-09-05 Tooth brush and process of making
US33093A (en) * 1861-08-20 Improvement in potato-diggers
US259268A (en) * 1882-06-06 Heney buozkowskt
US639376A (en) * 1899-04-21 1899-12-19 Charles L Goehring Brush.
US846900A (en) * 1906-02-06 1907-03-12 William O Bloom Tooth-brush.
US1411681A (en) * 1920-11-13 1922-04-04 Gilderoy O Burlew Dentifricial tablet
GB259268A (en) * 1925-06-05 1926-10-05 Cornelius Gordijn Junior Self-disinfecting brushes
US1673638A (en) * 1927-07-28 1928-06-12 Peterson Clifford Toothbrush
AT133093B (en) 1932-01-07 1933-04-25 Adolf Reiter Razor blade.
US2099888A (en) * 1933-12-15 1937-11-23 Prophylactic Brush Co Method of making self-sterilizing brushes
US2216333A (en) * 1936-06-13 1940-10-01 White Antisepticized brush
US2326774A (en) * 1939-07-11 1943-08-17 Benjamin H Freedman Safety razor
US2304478A (en) * 1939-10-19 1942-12-08 Rosenzweig Salo Process of treating materials comprising albumin, such as hair, bristles and the like
US2386085A (en) * 1943-07-07 1945-10-02 Byron A Babel Toothbrush
US2670489A (en) * 1946-04-11 1954-03-02 Kansas City Testing Lab Brush and synthetic bristles for imparting antiseptic properties
US2680290A (en) * 1949-02-01 1954-06-08 Steinberg Samuel Safety razor and blade therefor
US2667443A (en) * 1949-05-14 1954-01-26 Johnson & Johnson Dental floss
US2703451A (en) * 1950-03-04 1955-03-08 Hensel Herman Struve Cutting instrument having means for indicating usage
US2750664A (en) * 1953-11-16 1956-06-19 Mario P Merlo Indicator for razors
US2901392A (en) * 1954-07-14 1959-08-25 Gallowhur Chemical Corp Organic mercury solutions and method of preparing the same
US2938814A (en) * 1954-07-19 1960-05-31 Gallowhur Chemical Corp Method of producing antiseptic articles
US2965912A (en) * 1954-07-19 1960-12-27 Gallowhur Chemical Corp Antiseptic brushes and other articles
US2812575A (en) * 1954-11-04 1957-11-12 John C Abbott Razor blade counter
US2880129A (en) * 1956-01-19 1959-03-31 Johnson & Johnson Imparting anti-microbial properties to formed articles
US2939164A (en) * 1956-07-06 1960-06-07 Pycope Inc Antiseptic toothbrushes
US2885993A (en) * 1957-04-22 1959-05-12 Gadget Of The Month Club Inc Shave indicating device
US3067218A (en) * 1958-06-09 1962-12-04 Raymond L Pederson 2alpha, 17alpha-dimethyl derivatives of the androstane series
US3162572A (en) * 1961-11-27 1964-12-22 Standard Oil Co Hexachlorophene composition and method for rendering natural bristle bacteriostatic
US3380848A (en) * 1964-05-27 1968-04-30 Polymer Res Corp Of America Method of producing solid polymeric material having bactericidal properties
US3229659A (en) * 1964-09-22 1966-01-18 Peter D Sciascia Razor blade shave indicator
US3258805A (en) * 1964-11-04 1966-07-05 Rossnan Michael Tooth brush
US3934001A (en) * 1965-12-07 1976-01-20 Lever Brothers Company Oral compositions containing germicidally active plastic powders
US3394456A (en) * 1966-09-09 1968-07-30 Edward C. Gatz Razor guard to protectively cover a razor blade holder
US3512256A (en) * 1966-11-09 1970-05-19 Southeastern Coatings Inc Dry lubricant coated safety razor
DE1807299A1 (en) * 1968-11-06 1970-06-04 Bayer Ag Dentifrices containing exchange resins, dental aids, tooth filling compounds, tooth varnishes and other products that come into contact with living teeth
US3618563A (en) * 1970-01-15 1971-11-09 Michael B Singer Manual tally device
US3699979A (en) * 1971-04-08 1972-10-24 Indiana University Foundation Impregnated article for cleaning the interproximal surfaces of the teeth
US3771536A (en) * 1972-05-08 1973-11-13 W Dragan Dental floss and method of making same
US3830247A (en) * 1972-07-31 1974-08-20 P Kaphalakos Antiseptic dental floss
GB1367559A (en) * 1972-08-15 1974-09-18 Wilkinson Sword Ltd Razor blades
US3810479A (en) * 1972-10-17 1974-05-14 Colgate Palmolive Co Toothbrush having antimicrobial means
US3833008A (en) * 1972-11-09 1974-09-03 H Blackett Applicator for hair
US3898172A (en) * 1973-05-03 1975-08-05 Us Energy Irreversible humidity indicator
US3991766A (en) * 1973-05-31 1976-11-16 American Cyanamid Company Controlled release of medicaments using polymers from glycolic acid
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
US3897795A (en) * 1973-07-30 1975-08-05 Centrix Inc Dental floss and method of making same
US3992336A (en) * 1974-10-01 1976-11-16 Union Carbide Corporation Shaped article for conditioning hair fabricated from quaternary nitrogen-containing cellulose ether
US4018729A (en) * 1974-10-01 1977-04-19 Union Carbide Corporation Shaped article for conditioning hair a blend of water-soluble and water-insoluble polymers with interpenetrating networks
US3943949A (en) * 1974-11-26 1976-03-16 Johnson & Johnson Flavored dental articles
US4033365A (en) * 1976-01-23 1977-07-05 Johnson & Johnson Flavored dental articles
US4071645A (en) * 1976-03-12 1978-01-31 Acme Chemical Company Aqueous coating composition
US4170821A (en) * 1977-12-02 1979-10-16 Warner-Lambert Company Razor cartridges
GB2024082B (en) * 1978-05-31 1982-05-06 Gillette Co Safety razors
US4201599A (en) * 1978-07-06 1980-05-06 Trevor Morgans Restoration and protection of cutting surfaces
US4208984A (en) * 1978-10-12 1980-06-24 Norman Glanzman Razor usage indicator
US4257188A (en) * 1979-01-30 1981-03-24 Cpg Products Corp. Toy dolls and figurines having surface portions of reversibly changeable color
US4268958A (en) * 1979-11-01 1981-05-26 Ray Hilbert Apparatus and method for counting the number of shaves for which a razor blade is used
US4307739A (en) * 1980-05-27 1981-12-29 Chern Horng Y Hygienic comb and brush
IT1134586B (en) * 1980-12-04 1986-08-13 Renato Braga TOOTHBRUSH WITH SILVER BRISTLE HEAD
US4381293A (en) * 1982-01-11 1983-04-26 Michel George H Shaving composition
US4479501A (en) * 1982-04-16 1984-10-30 Chern Horng Y Cassette type hygienic comb and brush
US4685883A (en) * 1983-09-12 1987-08-11 Jernberg Gary R Local delivery of chemotherapeutic agents for the treatment of periodontal disease
US4892736A (en) * 1983-10-07 1990-01-09 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
FR2563142A1 (en) 1984-04-20 1985-10-25 Lehodey Philippe Mechanical shaver with a counter
US4517703A (en) * 1984-05-24 1985-05-21 Koke Eric J Hair brush with cleaning feature
US4604604A (en) * 1984-06-29 1986-08-05 International Harvester Company Vapor emitting wear indicator
US4586255A (en) * 1984-10-15 1986-05-06 The Gillette Company Razor blade assembly
US4624051A (en) * 1984-12-07 1986-11-25 The Gillette Company Shaving unit
FR2580478B1 (en) * 1985-04-17 1989-05-12 Christian Chapoton HAIR TREATMENT DEVICE RELEASING ACTIVE SUBSTANCE AND MANUFACTURING METHOD
US4759713A (en) * 1985-07-25 1988-07-26 Baxter Travenol Laboratories, Inc. Disposable dental tool
DE3533238A1 (en) 1985-09-18 1987-03-26 Moser Gmbh Kuno Electric shaver with shaving head
PH23397A (en) * 1985-12-11 1989-07-26 Unilever Nv Oral hygiene product
GB8601100D0 (en) * 1986-01-17 1986-02-19 Cosmas Damian Ltd Drug delivery system
US4697342A (en) * 1986-01-31 1987-10-06 Warner Lambert Company Cap for razor blade assembly adapted to receive an extra element
DE3604983A1 (en) 1986-02-17 1987-08-20 Bernstorff Graf Dominic Shaver with device for counting the number of shaves
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
USRE33093E (en) * 1986-06-16 1989-10-17 Johnson & Johnson Consumer Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4875287A (en) * 1986-11-14 1989-10-24 Hydromer, Inc. Shaving articles lubricious when wet and compositions therefor
US4931051A (en) * 1987-02-06 1990-06-05 Edge Enterprises, Inc. Wetness indicator
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
US4856541A (en) * 1987-08-06 1989-08-15 Creative Products Resource Associates, Ltd. Brush incorporating a hydrophilic foam pad for hair cleaning and conditioning
US5002075A (en) * 1987-08-06 1991-03-26 Creative Product Resource Associates, Ltd. Hydrophilic foam pad for hair styling, conditioning and coloring
US4802255A (en) * 1987-08-10 1989-02-07 Gillette Canada Inc. Novel brush filaments
US4978391A (en) * 1987-11-13 1990-12-18 Dentsply Management Corp. Intraoral medicament delivery and procedure
US5061106A (en) * 1988-03-08 1991-10-29 Colgate-Palmolive Company Toothbrush with slow release of disinfectant and antibacterial agents and method of manufacturing the same
US4986288A (en) * 1988-03-23 1991-01-22 Colgate-Palmolive Company Dental floss and picks
KR950010887B1 (en) * 1988-07-08 1995-09-25 Samsung Electronics Co Ltd Multi-screen producting image control circuit
US5049358A (en) * 1988-09-30 1991-09-17 Miles Inc. Composition and test device for assaying for proteins
US5240735A (en) * 1988-09-30 1993-08-31 Miles Inc. Method of manufacturing a test article for the determination of protein
US4872263A (en) * 1988-09-30 1989-10-10 The Kendall Company Lubricating device
FR2637528A1 (en) 1988-10-12 1990-04-13 Chailloux Jean Claude Device for counting the number of times that the blades of mechanical razors have been used
US5053339A (en) * 1988-11-03 1991-10-01 J P Labs Inc. Color changing device for monitoring shelf-life of perishable products
US5098711A (en) * 1988-11-14 1992-03-24 Ira Hill Method of treating the oral cavity with dental floss containing chemotherapeutic agents
US5228478A (en) * 1989-02-01 1993-07-20 Kleisle James R Wear indicator for material transfer systems
JPH0736718Y2 (en) * 1989-02-09 1995-08-23 パイロットインキ株式会社 Color memory toy supplies set
GB8905478D0 (en) * 1989-03-10 1989-04-19 Cogent Ltd Brushes
US4980150A (en) * 1989-04-27 1990-12-25 Zetachron, Inc. Chlorhexidine complex
US4941487A (en) * 1989-07-11 1990-07-17 Vanbeneden Floyd V Fluoridated dental floss
US5320824A (en) 1989-10-12 1994-06-14 Mallinckrodt Medical, Inc. Radionuclide labelled particles useful for radiation synovectomy
US5254473A (en) * 1990-03-16 1993-10-19 Jp Laboratories Solid state device for monitoring integral values of time and temperature of storage of perishables
US5096833A (en) * 1990-05-29 1992-03-17 Miles Inc. Method and device for determining protein using carrier matrix composed of urethane, water insouble inorganic compound and insoluble organic compound and method of making the device
US5062209A (en) * 1990-07-27 1991-11-05 Elliot Rais Use indicator for a disposable razor
US5113585A (en) * 1990-09-28 1992-05-19 The Gillette Company Shaving system
DE69127091T2 (en) 1990-09-28 1998-01-29 Gillette Co SHAVING SYSTEM
US5095619A (en) * 1990-09-28 1992-03-17 The Gillette Company Shaving system
JPH04193103A (en) * 1990-11-27 1992-07-13 Taisho Pharmaceut Co Ltd Antibacterial brush
US5119557A (en) * 1991-01-03 1992-06-09 John Kaiko Shave counter
US5340581A (en) * 1991-08-23 1994-08-23 Gillette Canada, Inc. Sustained-release matrices for dental application
KR100257842B1 (en) 1991-08-23 2000-06-01 질 시이 리차아드슨 Substained-release martrices
AU675206B2 (en) * 1991-09-13 1997-01-30 Gillette Canada Inc. Polymeric particles for dental applications
DE9200183U1 (en) 1992-01-09 1993-05-13 Wilkinson Sword Gmbh, 5650 Solingen, De
US5252577A (en) * 1992-03-06 1993-10-12 Gillette Canada, Inc. Methods of desensitizing teeth
US5313909A (en) * 1992-11-05 1994-05-24 Gillette Canada Inc. Brush filaments
US5240107A (en) * 1992-12-02 1993-08-31 James Casale Razor holder with shave counter
US5388331A (en) 1994-01-28 1995-02-14 Doroodian-Shoja Siamak Wear indicator for a disposable razor
US5454164A (en) 1994-03-17 1995-10-03 The Gillette Company Wet shaving system with a lubricating device
US5701921A (en) 1995-03-24 1997-12-30 Nacre Kit with toothbrush and toothpaste coordinated that end of working lives occur concurrently
US5851611A (en) 1995-06-05 1998-12-22 Alvin Guttag Multi-layered storage container
US5603161A (en) 1995-06-07 1997-02-18 Welsh; Christopher A. Wear indicating shaving strip and blade assembly for a shaver
US5837111A (en) 1996-01-19 1998-11-17 Ebert; William Arthur Corrosive mist scrubber
US5570325A (en) 1996-03-20 1996-10-29 Arpadi; Harry S. Tooth brushing timer
US5823891A (en) 1997-10-03 1998-10-20 Performance Dynamics, Llc Golf ball with water immersion indicator

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DK0600004T3 (en) 1999-08-16
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WO1993003649A1 (en) 1993-03-04
EP0600004A4 (en) 1995-12-20
CN1055827C (en) 2000-08-30
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JPH06509955A (en) 1994-11-10
CA2116115C (en) 2000-05-16
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US5723132A (en) 1998-03-03
MX9204878A (en) 1993-08-31
AU2498592A (en) 1993-03-16
ATE173893T1 (en) 1998-12-15
US5998431A (en) 1999-12-07
KR100257842B1 (en) 2000-06-01
AU667681B2 (en) 1996-04-04
EP0600004B1 (en) 1998-12-02
US5851551A (en) 1998-12-22
ES2124739T3 (en) 1999-02-16
DE9219148U1 (en) 1998-08-27
JP3523241B2 (en) 2004-04-26
CN1070323A (en) 1993-03-31
DE69227777D1 (en) 1999-01-14

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