US5079353A
(en)
*
|
1987-12-02 |
1992-01-07 |
Chembiomed, Ltd. |
Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
|
CA2110582C
(en)
*
|
1991-06-10 |
2001-02-27 |
Andre P. Venot |
Modified sialyl lewis a compounds
|
WO1992022565A1
(en)
*
|
1991-06-10 |
1992-12-23 |
Alberta Research Council |
Modified sialyl lewisx compounds
|
ES2129458T3
(en)
|
1991-10-15 |
1999-06-16 |
Scripps Research Inst |
PRODUCTION OF FUCOSILATED CARBOHYDRATES BY SYNTHESIS WITH ENZYMATIC FUCOSILATION OF SUGAR NUCLEOTIDES AND IN SITU REGENERATION OF GDP-FUCOSA.
|
WO1994010340A1
(en)
*
|
1992-10-30 |
1994-05-11 |
Mt. Sinai Hospital Corporation |
Method for measuring glycosyltransferase activity
|
US6406894B1
(en)
|
1992-12-11 |
2002-06-18 |
Glycorex Ab |
Process for preparing polyvalent and physiologically degradable carbohydrate-containing polymers by enzymatic glycosylation reactions and the use thereof for preparing carbohydrate building blocks
|
PL176272B1
(en)
*
|
1993-05-14 |
1999-05-31 |
Cytel Corp |
Sialylic le x analoques as inhibitors of cellular adhesion
|
US5854218A
(en)
*
|
1993-05-14 |
1998-12-29 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
US5811404A
(en)
*
|
1993-05-14 |
1998-09-22 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
US5559103A
(en)
*
|
1993-07-21 |
1996-09-24 |
Cytel Corporation |
Bivalent sialyl X saccharides
|
DE4431280A1
(en)
|
1994-09-02 |
1996-03-07 |
Hoechst Ag |
Process for the isolation and purification of nucleotide-activated sugars from biological sources
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
US5728554A
(en)
*
|
1995-04-11 |
1998-03-17 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
US5922577A
(en)
*
|
1995-04-11 |
1999-07-13 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
US6030815A
(en)
*
|
1995-04-11 |
2000-02-29 |
Neose Technologies, Inc. |
Enzymatic synthesis of oligosaccharides
|
US5876980A
(en)
*
|
1995-04-11 |
1999-03-02 |
Cytel Corporation |
Enzymatic synthesis of oligosaccharides
|
US5965544A
(en)
*
|
1995-09-29 |
1999-10-12 |
Glycim Oy |
Synthetic multivalent sLex containing polylactosamines and methods for use
|
AUPN658795A0
(en)
*
|
1995-11-15 |
1995-12-07 |
Commonwealth Scientific And Industrial Research Organisation |
Method of producing alpha 2, 3 sialyltransferase
|
US6841543B1
(en)
*
|
1996-01-31 |
2005-01-11 |
President And Fellows Of Harvard College |
Methods of inhibiting production of T helper type 2 cytokines in human immune cells
|
US6033663A
(en)
*
|
1996-04-10 |
2000-03-07 |
Neose Technologies, Inc. |
Nucleic acids encoding GDP-Fucose pyrophosphorylase
|
AU735695B2
(en)
*
|
1996-10-10 |
2001-07-12 |
Neose Technologies, Inc. |
Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration
|
ATE263841T1
(en)
*
|
1997-01-16 |
2004-04-15 |
Neose Technologies Inc |
PRACTICAL IN VITRO SIALYLATION OF RECOMBINANT GLYP PROTEINS
|
WO1999012944A2
(en)
|
1997-09-05 |
1999-03-18 |
Glycim Oy |
SYNTHETIC DIVALENT sLex CONTAINING POLYLACTOSAMINES AND METHODS FOR USE
|
EP1903114A3
(en)
|
1997-12-01 |
2008-07-23 |
Neose Technologies, Inc. |
Enzymatic synthesis of gangliosides
|
US7244601B2
(en)
*
|
1997-12-15 |
2007-07-17 |
National Research Council Of Canada |
Fusion proteins for use in enzymatic synthesis of oligosaccharides
|
US6500661B1
(en)
*
|
1998-01-15 |
2002-12-31 |
Neose Technologies, Inc. |
Enzymatic conversion of GDP-mannose to GDP-fucose
|
US6689604B1
(en)
*
|
1998-03-20 |
2004-02-10 |
National Research Council Of Canada |
Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses
|
US6194178B1
(en)
|
1998-09-03 |
2001-02-27 |
Synsorb Biotech Inc. |
Method for the production of sialylated oligosaccharides
|
US6503744B1
(en)
*
|
1999-02-01 |
2003-01-07 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
US6699705B2
(en)
*
|
1999-02-01 |
2004-03-02 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
US20030170828A1
(en)
*
|
2000-08-22 |
2003-09-11 |
Wei Zou |
Synthesis of complex carbohydrates
|
EP1425408A4
(en)
|
2001-08-17 |
2004-11-10 |
Neose Technologies Inc |
Chemo-enzymatic synthesis of sialylated oligosaccharides
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
CN101724075B
(en)
|
2001-10-10 |
2014-04-30 |
诺和诺德公司 |
Remodeling and glycoconjugation of peptides
|
EP2298354B1
(en)
|
2001-10-10 |
2014-03-19 |
ratiopharm GmbH |
Remodelling and glycoconjugation of interferon-beta
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7795210B2
(en)
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
CN100579577C
(en)
*
|
2002-03-15 |
2010-01-13 |
退伍军人事务研发服务部 |
Methods and compositions using cellular asialodeterminants and glycoconjugates for targeting cells to tissues and organs
|
US7060685B2
(en)
|
2002-05-16 |
2006-06-13 |
Glycomimetics, Inc. |
Compounds and methods for inhibiting selectin-mediated function
|
MXPA04012496A
(en)
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Pegylated factor vii glycoforms.
|
EP1539251A4
(en)
*
|
2002-07-03 |
2009-02-25 |
Glycomimetics Inc |
Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
|
MXPA05003843A
(en)
*
|
2002-10-10 |
2006-02-17 |
Us Dept Veterans Affairs |
Detection, localization and staging of tumors using labeled activated lymphocytes directed to a tumor specific epitope.
|
WO2004043405A2
(en)
|
2002-11-12 |
2004-05-27 |
The Brigham And Women's Hospital, Inc. |
Polysaccharide vaccine for staphylococcal infections
|
AU2004220087A1
(en)
|
2003-03-06 |
2004-09-23 |
Seneb Biosciences, Inc. |
Methods and compositions for the enzymatic synthesis of gangliosides
|
CA2519092C
(en)
|
2003-03-14 |
2014-08-05 |
Neose Technologies, Inc. |
Branched water-soluble polymers and their conjugates
|
US20070026485A1
(en)
|
2003-04-09 |
2007-02-01 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7691603B2
(en)
*
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US20040219158A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria
|
BRPI0410164A
(en)
|
2003-05-09 |
2006-05-16 |
Neose Technologies Inc |
compositions and methods for preparing human growth hormone glycosylation mutants
|
US9005625B2
(en)
|
2003-07-25 |
2015-04-14 |
Novo Nordisk A/S |
Antibody toxin conjugates
|
JP4566194B2
(en)
*
|
2003-08-12 |
2010-10-20 |
リポクセン テクノロジーズ リミテッド |
Sialic acid derivatives for protein derivatization and conjugation
|
JP2007524658A
(en)
*
|
2003-11-19 |
2007-08-30 |
グリコミメティクス, インコーポレイテッド |
Glucose mimetic antagonists for both E- and P-selectin
|
ATE383367T1
(en)
*
|
2003-11-19 |
2008-01-15 |
Glycomimetics Inc |
SPECIFIC ANTAGONIST FOR BOTH E- AND P-SELECTINS
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US7842661B2
(en)
|
2003-11-24 |
2010-11-30 |
Novo Nordisk A/S |
Glycopegylated erythropoietin formulations
|
US20070254834A1
(en)
*
|
2003-11-24 |
2007-11-01 |
Defrees Shawn |
Glycopegylated Erythropoietin
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
CA2552892C
(en)
|
2004-01-08 |
2014-08-05 |
Neose Technologies, Inc. |
O-linked glycosylation of peptides
|
AU2005222782B2
(en)
|
2004-02-04 |
2010-06-17 |
Ratiopharm Gmbh |
Methods of refolding mammalian glycosyltransferases
|
RU2006138181A
(en)
|
2004-05-04 |
2008-06-10 |
Ново Нордиск Хелс Кеа Аг (Ch) |
O-RELATED Glycoforms of Polypeptides and a Method for Their Production
|
US20080300173A1
(en)
|
2004-07-13 |
2008-12-04 |
Defrees Shawn |
Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
|
EP1799249A2
(en)
|
2004-09-10 |
2007-06-27 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
JP2008514215A
(en)
*
|
2004-09-29 |
2008-05-08 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
Modified protein
|
US20080176790A1
(en)
|
2004-10-29 |
2008-07-24 |
Defrees Shawn |
Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf)
|
EP1858543B1
(en)
|
2005-01-10 |
2013-11-27 |
BioGeneriX AG |
Glycopegylated granulocyte colony stimulating factor
|
EP1866427A4
(en)
*
|
2005-03-30 |
2010-09-01 |
Novo Nordisk As |
Manufacturing process for the production of peptides grown in insect cell lines
|
US9187546B2
(en)
|
2005-04-08 |
2015-11-17 |
Novo Nordisk A/S |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
WO2006127906A1
(en)
*
|
2005-05-25 |
2006-11-30 |
Glycomimetics, Inc. |
Heterobifunctional compounds for selectin inhibition
|
US20080255026A1
(en)
|
2005-05-25 |
2008-10-16 |
Glycopegylated Factor 1X |
Glycopegylated Factor Ix
|
ES2375979T3
(en)
*
|
2005-08-09 |
2012-03-07 |
Glycomimetics, Inc. |
GLICOMIMETIC INHIBITORS OF PA-IL LECTIN, PA-IIL LECTIN OR BOTH LECTINES OF PSEUDOMONES.
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
CN102719508A
(en)
*
|
2005-08-19 |
2012-10-10 |
诺和诺德公司 |
Glycopegylated factor VII and factor VIIA
|
CN103626813B
(en)
|
2005-09-02 |
2017-05-03 |
糖模拟物有限公司 |
Heterobifunctional pan-selectin inhibitors
|
US20090048440A1
(en)
*
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
WO2007143052A1
(en)
*
|
2006-06-01 |
2007-12-13 |
Glycomimetics, Inc. |
Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas
|
CN101516388B
(en)
*
|
2006-07-21 |
2012-10-31 |
诺和诺德公司 |
Glycosylation of peptides via O-linked glycosylation sequences
|
US8969532B2
(en)
|
2006-10-03 |
2015-03-03 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
|
CA2665480C
(en)
|
2006-10-04 |
2019-11-12 |
Shawn Defrees |
Glycerol linked pegylated sugars and glycopeptides
|
JP5298020B2
(en)
|
2006-10-12 |
2013-09-25 |
グリコミメティクス, インコーポレイテッド |
Glucose mimic substitution of hexose and N-acetylhexosamine
|
WO2008073620A2
(en)
*
|
2006-11-02 |
2008-06-19 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
WO2008100453A1
(en)
*
|
2007-02-09 |
2008-08-21 |
Glycomimetics, Inc. |
Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines
|
DK2144923T3
(en)
|
2007-04-03 |
2013-05-13 |
Biogenerix Ag |
METHODS OF TREATMENT WITH USING GLYCOPEGYLATED G-CSF
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
ES2551123T3
(en)
|
2007-06-12 |
2015-11-16 |
Ratiopharm Gmbh |
Improved process for the production of nucleotide sugars
|
US8039442B2
(en)
*
|
2007-07-18 |
2011-10-18 |
Glycomimetics, Inc. |
Compounds and methods for treatment of sickle cell disease or complications associated therewith
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
CN101965200B
(en)
|
2008-02-27 |
2013-06-19 |
诺沃-诺迪斯克有限公司 |
Conjugated factor VIII molecules
|
WO2009126556A1
(en)
*
|
2008-04-08 |
2009-10-15 |
Glycomimetics, Inc. |
Pan-selectin inhibitor with enhanced pharmacokinetic activity
|
EP2279249A4
(en)
|
2008-05-30 |
2014-03-05 |
Momenta Pharmaceuticals Inc |
Saccharide structures and methods of making and using such structures
|
ES2426784T3
(en)
*
|
2008-06-13 |
2013-10-25 |
Glycomimetics, Inc. |
Treatment of blood cancers using selected glyomimetic compounds
|
KR20150041178A
(en)
|
2008-07-21 |
2015-04-15 |
더 브리검 앤드 우먼즈 하스피털, 인크. |
Methods and compositions relating to synthetic beta-1,6 glucosamine oligosaccharides
|
CA2760292A1
(en)
*
|
2009-05-01 |
2010-11-04 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
|
WO2012037034A1
(en)
|
2010-09-14 |
2012-03-22 |
Glycomimetics, Inc. |
E-selectin antagonists
|
EP2794626B3
(en)
|
2011-12-22 |
2020-08-05 |
GlycoMimetics, Inc. |
E-selectin antagonist compounds
|
EP2698636A1
(en)
*
|
2012-08-13 |
2014-02-19 |
Fundació Institut d'Investigació Biomèdica de Bellvitge |
Methods and reagents for prevention and/or treatment of transplant rejection
|
CA2891514C
(en)
|
2012-12-07 |
2020-08-25 |
Glycomimetics, Inc. |
Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
|
HUE045542T2
(en)
|
2014-12-03 |
2019-12-30 |
Glycomimetics Inc |
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
|
US11045485B2
(en)
|
2016-01-22 |
2021-06-29 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of PA-IL and PA-IIL lectins
|
US11291678B2
(en)
|
2016-03-02 |
2022-04-05 |
Glycomimetics, Inc |
Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
|
WO2018031445A1
(en)
|
2016-08-08 |
2018-02-15 |
Glycomimetics, Inc. |
Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4
|
CA3037850A1
(en)
|
2016-10-07 |
2018-04-12 |
Glycomimetics, Inc. |
Highly potent multimeric e-selectin antagonists
|
US11197877B2
(en)
|
2017-03-15 |
2021-12-14 |
Glycomimetics. Inc. |
Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists
|
US11712446B2
(en)
|
2017-11-30 |
2023-08-01 |
Glycomimetics, Inc. |
Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
|
WO2019133878A1
(en)
|
2017-12-29 |
2019-07-04 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of e-selectin and galectin-3
|
WO2019173229A1
(en)
|
2018-03-05 |
2019-09-12 |
Glycomimetics, Inc. |
Methods for treating acute myeloid leukemia and related conditions
|
US11845771B2
(en)
|
2018-12-27 |
2023-12-19 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectin and galectin-3
|