US5079353A
(en)
*
|
1987-12-02 |
1992-01-07 |
Chembiomed, Ltd. |
Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
|
JPH06510744A
(en)
*
|
1991-06-10 |
1994-12-01 |
グライカムド インコーポレイテッド |
Modified sialyl Lewis x compound
|
EP0588848A1
(en)
*
|
1991-06-10 |
1994-03-30 |
Glycomed Incorporated |
Modified sialyl lewis?a compounds
|
JPH07500248A
(en)
|
1991-10-15 |
1995-01-12 |
ザ スクリップス リサーチ インスティテュート |
Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides and in situ regeneration of GDP-fucose
|
WO1994010340A1
(en)
*
|
1992-10-30 |
1994-05-11 |
Mt. Sinai Hospital Corporation |
Method for measuring glycosyltransferase activity
|
US6406894B1
(en)
|
1992-12-11 |
2002-06-18 |
Glycorex Ab |
Process for preparing polyvalent and physiologically degradable carbohydrate-containing polymers by enzymatic glycosylation reactions and the use thereof for preparing carbohydrate building blocks
|
SK141695A3
(en)
*
|
1993-05-14 |
1996-10-02 |
Cytel Corp |
Analogous compound sialyl lex, pharmaceutical agent containing this compound and method of preparation of lactoseammoniacal salt
|
US5811404A
(en)
*
|
1993-05-14 |
1998-09-22 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
US5854218A
(en)
*
|
1993-05-14 |
1998-12-29 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
US5559103A
(en)
*
|
1993-07-21 |
1996-09-24 |
Cytel Corporation |
Bivalent sialyl X saccharides
|
DE4431280A1
(en)
|
1994-09-02 |
1996-03-07 |
Hoechst Ag |
Process for the isolation and purification of nucleotide-activated sugars from biological sources
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
US6030815A
(en)
*
|
1995-04-11 |
2000-02-29 |
Neose Technologies, Inc. |
Enzymatic synthesis of oligosaccharides
|
US5876980A
(en)
*
|
1995-04-11 |
1999-03-02 |
Cytel Corporation |
Enzymatic synthesis of oligosaccharides
|
US5728554A
(en)
*
|
1995-04-11 |
1998-03-17 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
US5922577A
(en)
*
|
1995-04-11 |
1999-07-13 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
EP0874861A1
(en)
*
|
1995-09-29 |
1998-11-04 |
Glycim Oy |
Synthetic multivalent slex containing polylactosamines and methods for use
|
AUPN658795A0
(en)
*
|
1995-11-15 |
1995-12-07 |
Commonwealth Scientific And Industrial Research Organisation |
Method of producing alpha 2, 3 sialyltransferase
|
US6841543B1
(en)
*
|
1996-01-31 |
2005-01-11 |
President And Fellows Of Harvard College |
Methods of inhibiting production of T helper type 2 cytokines in human immune cells
|
US6033663A
(en)
*
|
1996-04-10 |
2000-03-07 |
Neose Technologies, Inc. |
Nucleic acids encoding GDP-Fucose pyrophosphorylase
|
WO1998015581A1
(en)
|
1996-10-10 |
1998-04-16 |
Cytel Corporation |
Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration
|
WO1998031826A1
(en)
*
|
1997-01-16 |
1998-07-23 |
Cytel Corporation |
Practical in vitro sialylation of recombinant glycoproteins
|
AU9073998A
(en)
|
1997-09-05 |
1999-03-29 |
Glycim Oy |
Synthetic divalent slex containing polylactosamines and methods for use
|
EP1903114A3
(en)
|
1997-12-01 |
2008-07-23 |
Neose Technologies, Inc. |
Enzymatic synthesis of gangliosides
|
US7244601B2
(en)
*
|
1997-12-15 |
2007-07-17 |
National Research Council Of Canada |
Fusion proteins for use in enzymatic synthesis of oligosaccharides
|
US6500661B1
(en)
|
1998-01-15 |
2002-12-31 |
Neose Technologies, Inc. |
Enzymatic conversion of GDP-mannose to GDP-fucose
|
US6689604B1
(en)
*
|
1998-03-20 |
2004-02-10 |
National Research Council Of Canada |
Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses
|
US6194178B1
(en)
|
1998-09-03 |
2001-02-27 |
Synsorb Biotech Inc. |
Method for the production of sialylated oligosaccharides
|
US6503744B1
(en)
*
|
1999-02-01 |
2003-01-07 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
US6699705B2
(en)
*
|
1999-02-01 |
2004-03-02 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
EP1311550A2
(en)
*
|
2000-08-22 |
2003-05-21 |
National Research Council Of Canada |
Synthesis of complex carbohydrates
|
AU2002330968B2
(en)
|
2001-08-17 |
2007-03-22 |
Neose Technologies, Inc. |
Chemo-enzymatic synthesis of sialylated oligosaccharides
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
NZ532027A
(en)
*
|
2001-10-10 |
2008-09-26 |
Neose Technologies Inc |
Remodeling and glycoconjugation of peptides
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7795210B2
(en)
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
CN105131104B
(en)
|
2001-10-10 |
2018-11-16 |
诺和诺德公司 |
The reconstruct and sugar conjugation of peptide
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
AU2003267949A1
(en)
*
|
2002-03-15 |
2003-12-31 |
U.S. Government As Represented By The Department Of Veterans Affairs |
Methods and compositions using cellular asialodeterminants and glycoconjugates for targeting cells to tissues and organs
|
US7060685B2
(en)
*
|
2002-05-16 |
2006-06-13 |
Glycomimetics, Inc. |
Compounds and methods for inhibiting selectin-mediated function
|
DE60336555D1
(en)
|
2002-06-21 |
2011-05-12 |
Novo Nordisk Healthcare Ag |
PEGYLATED GLYCO FORMS OF FACTOR VII
|
WO2004004636A2
(en)
*
|
2002-07-03 |
2004-01-15 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
|
CN1711475A
(en)
*
|
2002-10-10 |
2005-12-21 |
退伍军人事务部 |
Detection, localization and staging of tumors using labeled activated lymphocytes directed to a tumor specific epitope
|
BRPI0316018B8
(en)
|
2002-11-12 |
2021-05-25 |
Brigham & Womens Hospital Inc |
polysaccharide vaccine for staphylococcal infections
|
JP2006519878A
(en)
|
2003-03-06 |
2006-08-31 |
ネオーズ テクノロジーズ, インコーポレイテッド |
Methods and compounds for enzymatic synthesis of gangliosides
|
KR20060003862A
(en)
|
2003-03-14 |
2006-01-11 |
네오스 테크놀로지스, 인크. |
Branched water-soluble polymers and their eonjugates
|
US7691603B2
(en)
*
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
US20070026485A1
(en)
|
2003-04-09 |
2007-02-01 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
WO2006127896A2
(en)
*
|
2005-05-25 |
2006-11-30 |
Neose Technologies, Inc. |
Glycopegylated factor ix
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US20040219158A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria
|
US7932364B2
(en)
|
2003-05-09 |
2011-04-26 |
Novo Nordisk A/S |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
WO2005016974A1
(en)
*
|
2003-08-12 |
2005-02-24 |
Lipoxen Technologies Limited |
Sialic acid derivatives for protein derivatisation and conjugation
|
WO2005051920A2
(en)
*
|
2003-11-19 |
2005-06-09 |
Glycomimetics, Inc. |
Specific antagonist for both e- and p-selectins
|
JP2007524658A
(en)
*
|
2003-11-19 |
2007-08-30 |
グリコミメティクス, インコーポレイテッド |
Glucose mimetic antagonists for both E- and P-selectin
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
EP1694347B1
(en)
*
|
2003-11-24 |
2013-11-20 |
BioGeneriX AG |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
KR101439880B1
(en)
|
2004-01-08 |
2014-09-12 |
라티오팜 게엠베하 |
O-linked glycosylation of peptides
|
EP2484759B1
(en)
|
2004-02-04 |
2014-06-25 |
ratiopharm GmbH |
Methods of refolding mammalian glycosyltransferases
|
ATE455861T1
(en)
|
2004-05-04 |
2010-02-15 |
Novo Nordisk Healthcare Ag |
O-LINKED GLYCOFORMS OF FACTOR VII AND METHOD FOR THE PRODUCTION THEREOF
|
EP1771066A2
(en)
|
2004-07-13 |
2007-04-11 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 glp-1
|
US8268967B2
(en)
|
2004-09-10 |
2012-09-18 |
Novo Nordisk A/S |
Glycopegylated interferon α
|
JP2008514215A
(en)
*
|
2004-09-29 |
2008-05-08 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
Modified protein
|
ES2572779T3
(en)
|
2004-10-29 |
2016-06-02 |
Ratiopharm Gmbh |
Remodeling and glucopegilation of Fibroblast Growth Factor (FGF)
|
ES2449195T3
(en)
|
2005-01-10 |
2014-03-18 |
Ratiopharm Gmbh |
Glycopegylated granulocyte colony stimulating factor
|
US20060246544A1
(en)
*
|
2005-03-30 |
2006-11-02 |
Neose Technologies,Inc. |
Manufacturing process for the production of peptides grown in insect cell lines
|
EP2386571B1
(en)
|
2005-04-08 |
2016-06-01 |
ratiopharm GmbH |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
EP1888098A2
(en)
|
2005-05-25 |
2008-02-20 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin formulations
|
US20090036386A1
(en)
*
|
2005-05-25 |
2009-02-05 |
Glycomimetics, Inc |
Heterobifunctional compounds for selectin inhibition
|
DK1928892T3
(en)
*
|
2005-08-09 |
2012-01-30 |
Glycomimetics Inc |
Glycomimetic inhibitors of PA-IL lectin PA-IIL lectin or both pseudomonas lectins
|
KR20080080081A
(en)
*
|
2005-08-19 |
2008-09-02 |
네오스 테크놀로지스, 인크. |
Glycopegylated factor vii and factor viia
|
US20070105755A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
PL1934236T3
(en)
|
2005-09-02 |
2013-04-30 |
Glycomimetics Inc |
Heterobifunctional pan-selectin inhibitors
|
US20090048440A1
(en)
*
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
US20090176717A1
(en)
*
|
2006-06-01 |
2009-07-09 |
Glycomimetics, Inc. |
Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas
|
US9187532B2
(en)
|
2006-07-21 |
2015-11-17 |
Novo Nordisk A/S |
Glycosylation of peptides via O-linked glycosylation sequences
|
EP2054521A4
(en)
|
2006-10-03 |
2012-12-19 |
Novo Nordisk As |
Methods for the purification of polypeptide conjugates
|
JP5457185B2
(en)
|
2006-10-04 |
2014-04-02 |
ノヴォ ノルディスク アー/エス |
Glycerol-linked PEGylated sugars and glycopeptides
|
JP5298020B2
(en)
|
2006-10-12 |
2013-09-25 |
グリコミメティクス, インコーポレイテッド |
Glucose mimic substitution of hexose and N-acetylhexosamine
|
WO2008073620A2
(en)
*
|
2006-11-02 |
2008-06-19 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
AU2008216794A1
(en)
*
|
2007-02-09 |
2008-08-21 |
Glycomimetics, Inc. |
Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines
|
CA2682897C
(en)
|
2007-04-03 |
2016-11-22 |
Biogenerix Ag |
Methods of treatment using glycopegylated g-csf
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
CN101778859B
(en)
|
2007-06-12 |
2014-03-26 |
诺和诺德公司 |
Improved process for the production of nucleotide sugars
|
US8039442B2
(en)
*
|
2007-07-18 |
2011-10-18 |
Glycomimetics, Inc. |
Compounds and methods for treatment of sickle cell disease or complications associated therewith
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
US20130189239A1
(en)
|
2008-02-27 |
2013-07-25 |
Novo Nordisk A/S |
Conjugated Factor VIII Molecules
|
WO2009126556A1
(en)
|
2008-04-08 |
2009-10-15 |
Glycomimetics, Inc. |
Pan-selectin inhibitor with enhanced pharmacokinetic activity
|
JP2011522805A
(en)
|
2008-05-30 |
2011-08-04 |
モメンタ ファーマシューティカルズ インコーポレイテッド |
Sugar structures and methods of making and using such structures
|
EP2318015B1
(en)
*
|
2008-06-13 |
2013-08-07 |
GlycoMimetics, Inc. |
Treatment of cancers of the blood using selected glycomimetic compounds
|
BRPI0916365A2
(en)
|
2008-07-21 |
2018-05-02 |
Brigham & Womens Hospital Inc |
methods and compositions related to synthetic beta-1,6 glycosine oligosaccharides
|
JP5726171B2
(en)
*
|
2009-05-01 |
2015-05-27 |
グリコミメティックス インコーポレイテッド |
Heterobifunctional inhibitors of E-selectin and CXCR4 chemokine receptors
|
US8921328B2
(en)
|
2010-09-14 |
2014-12-30 |
Glycomimetics, Inc. |
E-selectin antagonists
|
WO2013096926A1
(en)
|
2011-12-22 |
2013-06-27 |
Glycomimetics, Inc. |
E-selectin antagonist compounds, compositions, and methods of use
|
EP2698636A1
(en)
*
|
2012-08-13 |
2014-02-19 |
Fundació Institut d'Investigació Biomèdica de Bellvitge |
Methods and reagents for prevention and/or treatment of transplant rejection
|
LT2928476T
(en)
|
2012-12-07 |
2018-05-25 |
Glycomimetics, Inc. |
Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
|
SI3227310T1
(en)
|
2014-12-03 |
2019-11-29 |
Glycomimetics Inc |
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
|
WO2017127422A1
(en)
|
2016-01-22 |
2017-07-27 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of pa-il and pa-iil lectins
|
US11291678B2
(en)
|
2016-03-02 |
2022-04-05 |
Glycomimetics, Inc |
Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
|
JP2019524791A
(en)
|
2016-08-08 |
2019-09-05 |
グリコミメティクス, インコーポレイテッド |
Combinations of T cell checkpoint inhibitors with inhibitors of E-selectin or inhibitors of CXCR4 or with heterobifunctional inhibitors of both E-selectin and CXCR4
|
KR20240046288A
(en)
|
2016-10-07 |
2024-04-08 |
글리코미메틱스, 인크. |
Highly potent multimeric e-selectin antagonists
|
CA3054605A1
(en)
|
2017-03-15 |
2018-09-20 |
Glycomimetics, Inc. |
Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
|
WO2019108750A1
(en)
|
2017-11-30 |
2019-06-06 |
Glycomimetics, Inc. |
Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
|
JP7304863B2
(en)
|
2017-12-29 |
2023-07-07 |
グリコミメティクス, インコーポレイテッド |
Heterobifunctional inhibitors of E-selectin and galectin-3
|
US11707474B2
(en)
|
2018-03-05 |
2023-07-25 |
Glycomimetics, Inc. |
Methods for treating acute myeloid leukemia and related conditions
|
US11845771B2
(en)
|
2018-12-27 |
2023-12-19 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectin and galectin-3
|