CA2107108A1 - Improvements in or relating to contrast agents - Google Patents

Improvements in or relating to contrast agents

Info

Publication number
CA2107108A1
CA2107108A1 CA002107108A CA2107108A CA2107108A1 CA 2107108 A1 CA2107108 A1 CA 2107108A1 CA 002107108 A CA002107108 A CA 002107108A CA 2107108 A CA2107108 A CA 2107108A CA 2107108 A1 CA2107108 A1 CA 2107108A1
Authority
CA
Canada
Prior art keywords
contrast agents
relating
gas
microbubbles
biodegradability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002107108A
Other languages
French (fr)
Other versions
CA2107108C (en
Inventor
Jo Klaveness
Hanno Priebe
Pal Rongved
Lars Stubberud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Amersham Health As
Jo Klaveness
Hanno Priebe
Pal Rongved
Lars Stubberud
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10692381&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2107108(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham Health As, Jo Klaveness, Hanno Priebe, Pal Rongved, Lars Stubberud, Nycomed Imaging As filed Critical Amersham Health As
Publication of CA2107108A1 publication Critical patent/CA2107108A1/en
Application granted granted Critical
Publication of CA2107108C publication Critical patent/CA2107108C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Valves And Accessory Devices For Braking Systems (AREA)
  • Valve-Gear Or Valve Arrangements (AREA)
  • Electroluminescent Light Sources (AREA)
  • Glass Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

Ultrasound contrast agents having microbubbles of gas or a gas precursor encapsulated by non-proteinaceous crosslinked or polymerised amphiphilic moieties, e.g. in the form of micelles, exhibit good stability in vivo upon administration and may if desired incorporate biodegradable linkages so as to possess particular desired levels of biodegradability.
CA002107108A 1991-03-28 1992-03-28 Improvements in or relating to contrast agents Expired - Fee Related CA2107108C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9106673.8 1991-03-28
GB919106673A GB9106673D0 (en) 1991-03-28 1991-03-28 Improvements in or relating to contrast agents
PCT/EP1992/000715 WO1992017212A1 (en) 1991-03-28 1992-03-28 Improvements in or relating to contrast agents

Publications (2)

Publication Number Publication Date
CA2107108A1 true CA2107108A1 (en) 1992-09-29
CA2107108C CA2107108C (en) 2002-11-12

Family

ID=10692381

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002107108A Expired - Fee Related CA2107108C (en) 1991-03-28 1992-03-28 Improvements in or relating to contrast agents

Country Status (16)

Country Link
US (6) US5536490A (en)
EP (1) EP0576519B1 (en)
JP (1) JP3424927B2 (en)
AT (1) ATE200628T1 (en)
AU (1) AU667033B2 (en)
CA (1) CA2107108C (en)
DE (1) DE69231794T2 (en)
DK (1) DK0576519T3 (en)
ES (1) ES2156109T3 (en)
FI (1) FI934226A (en)
GB (1) GB9106673D0 (en)
GR (1) GR3035829T3 (en)
HK (1) HK1004980A1 (en)
NO (1) NO324068B1 (en)
SG (1) SG43907A1 (en)
WO (1) WO1992017212A1 (en)

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FI934226A0 (en) 1993-09-27
JP3424927B2 (en) 2003-07-07
US5536490A (en) 1996-07-16
NO933431L (en) 1993-09-27
GB9106673D0 (en) 1991-05-15
ATE200628T1 (en) 2001-05-15
US20040131548A1 (en) 2004-07-08
CA2107108C (en) 2002-11-12
AU667033B2 (en) 1996-03-07
AU1425392A (en) 1992-11-02
DE69231794T2 (en) 2001-11-22
NO324068B1 (en) 2007-08-06
SG43907A1 (en) 1997-11-14
US20070014731A1 (en) 2007-01-18
GR3035829T3 (en) 2001-08-31
DK0576519T3 (en) 2001-06-18
ES2156109T3 (en) 2001-06-16
WO1992017212A1 (en) 1992-10-15
US6106806A (en) 2000-08-22
FI934226A (en) 1993-09-27
US20020172643A1 (en) 2002-11-21
HK1004980A1 (en) 1998-12-18
NO933431D0 (en) 1993-09-27
EP0576519A1 (en) 1994-01-05
US5567413A (en) 1996-10-22
DE69231794D1 (en) 2001-05-23
EP0576519B1 (en) 2001-04-18
JPH06507884A (en) 1994-09-08

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