CA2099920A1 - Modified Chlorhexidine-Adduct - Google Patents

Modified Chlorhexidine-Adduct

Info

Publication number
CA2099920A1
CA2099920A1 CA2099920A CA2099920A CA2099920A1 CA 2099920 A1 CA2099920 A1 CA 2099920A1 CA 2099920 A CA2099920 A CA 2099920A CA 2099920 A CA2099920 A CA 2099920A CA 2099920 A1 CA2099920 A1 CA 2099920A1
Authority
CA
Canada
Prior art keywords
adduct
chlorhexidine
molecule
modified
modified chlorhexidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2099920A
Other languages
French (fr)
Other versions
CA2099920C (en
Inventor
Volker Rheinberger
Ulrich Salz
Peter Burtscher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ivoclar AG
Original Assignee
Ivoclar AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivoclar AG filed Critical Ivoclar AG
Publication of CA2099920A1 publication Critical patent/CA2099920A1/en
Application granted granted Critical
Publication of CA2099920C publication Critical patent/CA2099920C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups

Abstract

A chlorhexidine adduct is described, which comprises one molecule of chlorhexidine with three molecules of hydrogen fluoride and one molecule of hydrogen tin trifluoride. The adduct displays a high antibacterial effectiveness against Streptococcus mutans even in very low concentrations.
CA002099920A 1992-07-08 1993-07-06 Modified chlorhexidine-adduct Expired - Fee Related CA2099920C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4222821A DE4222821C2 (en) 1992-07-08 1992-07-08 Modified chlorhexidine adduct
DEP4222821.2 1992-07-08

Publications (2)

Publication Number Publication Date
CA2099920A1 true CA2099920A1 (en) 1994-01-09
CA2099920C CA2099920C (en) 1996-12-24

Family

ID=6462979

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002099920A Expired - Fee Related CA2099920C (en) 1992-07-08 1993-07-06 Modified chlorhexidine-adduct

Country Status (6)

Country Link
US (1) US5393516A (en)
EP (1) EP0578344B1 (en)
AT (1) ATE141912T1 (en)
AU (1) AU655547B2 (en)
CA (1) CA2099920C (en)
DE (2) DE4222821C2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA965340B (en) * 1995-06-30 1997-01-27 Interdigital Tech Corp Code division multiple access (cdma) communication system
US6293287B1 (en) * 1996-09-13 2001-09-25 Gillette Canada Inc. UV-cured resin-coated dental floss
US5967153A (en) * 1996-10-15 1999-10-19 Gillette Canada Inc. Emulsion coated dental floss containing chemotherapeutic active agents
US6726899B2 (en) 1998-09-24 2004-04-27 Advantage Dental Products, Inc. Calcified tissue facing preparation containing antimicrobial agent
CA2344697C (en) * 1998-09-24 2012-11-13 Advantage Dental Products, Inc. Calcified tissue facing preparation containing an antimicrobial agent
DE19921727A1 (en) * 1999-05-12 2000-11-16 Susanne Szep Fluoriding composition for treating tooth surfaces to prevent caries and reduce sensitivity, containing hydrogen fluoride to form strongly bound fluoride complexes on surface
DE19921950A1 (en) * 1999-05-12 2000-11-16 Susanne Szep Dentine adhesives containing hydrogen fluoride for use in dental restorative work
US20030162839A1 (en) * 2000-04-03 2003-08-28 Symington John Marston Use of chlorhexidine in the prevention of root caries
DE10261241A1 (en) * 2002-12-20 2004-07-15 3M Espe Ag Dental material with bacteriostatic and / or bactericidal substances
US20060254988A1 (en) * 2005-05-10 2006-11-16 Confirm Monitoring Systems, Inc. Methods and compositions for the treatment of water
EP1787627A1 (en) 2005-11-17 2007-05-23 3M Innovative Properties Company Anti-microbial dental impression material
AU2006325820B2 (en) * 2005-12-12 2013-02-14 Allaccem, Inc. Methods and systems for preparing antimicrobial films and coatings
CA2683383C (en) 2007-02-21 2016-01-05 Allaccem, Incorporated Bridged polycyclic compound based compositions for the inhibition and amelioration of disease
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
WO2009158564A1 (en) * 2008-06-27 2009-12-30 Novamin Technology, Inc. Composition and method for enhancing flouride uptake using bioactive glass
US10159548B2 (en) 2014-09-17 2018-12-25 Garrison Dental Solutions, L.L.C. Dental curing light
RU2696259C2 (en) 2017-10-23 2019-08-01 Общество С Ограниченной Ответственностью "Сан Системз" Solubilization of the chlorhexidine base, antiseptic and disinfectant compositions
DE102019000321A1 (en) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Oral sustained release polymer composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1304090A (en) * 1970-11-27 1973-01-24
US4069310A (en) * 1970-11-27 1978-01-17 Colgate Palmolive Company Method for the manufacture of clear dentifrices
US5098711A (en) * 1988-11-14 1992-03-24 Ira Hill Method of treating the oral cavity with dental floss containing chemotherapeutic agents
DE4135397C2 (en) * 1991-10-26 1994-01-20 Ivoclar Ag Schaan Chlorhexidine adduct, process for its preparation and its use

Also Published As

Publication number Publication date
EP0578344A1 (en) 1994-01-12
US5393516A (en) 1995-02-28
DE4222821C2 (en) 1994-09-22
EP0578344B1 (en) 1996-08-28
DE59303552D1 (en) 1996-10-02
CA2099920C (en) 1996-12-24
DE4222821A1 (en) 1994-01-13
AU4150893A (en) 1994-01-13
ATE141912T1 (en) 1996-09-15
AU655547B2 (en) 1994-12-22

Similar Documents

Publication Publication Date Title
CA2099920A1 (en) Modified Chlorhexidine-Adduct
AU8130494A (en) Topical antimicrobial cleanser containing chlorhexidine gluconate and alcohol
CA2168248A1 (en) Antifungal Nail Solution
CA2011428A1 (en) Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants
CA2028570A1 (en) Antimicrobial method and formulation employing type ii endoglycosidase and antimicrobial agent
AU6291094A (en) Refrigerator lubricant and refrigerant composition containing the same
IL106132A0 (en) Refrigerant composition containing 1,1,1,2,3,3,3-heptafluoropropane and methods utilizing the same
CA2180554A1 (en) Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
SG49874A1 (en) Topical composition containing hyaluronic acid and nsaids
CA2162128A1 (en) Quaternary ammonium and waterproofing/preservative compositions
CA2151937A1 (en) Antiplaque, antigingivitis, anticaries oral composition
AU6218996A (en) Prevention and treatment of topical viral infections with perfluoropolyethers or compositions thereof
CA2214713A1 (en) Topical antimicrobial agents
AU6834294A (en) Metal chelates as spacer compounds in biologically active peptides
EP0539811A3 (en) Chlorhexidine adduct
CA2037150A1 (en) Retinoids
AU6188294A (en) Cryogenic liquid dispensers
CA2121123A1 (en) Anti-seborrhoeic formulation
CA2179778A1 (en) Deuterised active agents in transdermal application
AU3465393A (en) Pharmaceutic composition and its use
USD353896S (en) Window frame extrusion
AU6273794A (en) Organic peroxide compositions and process therefor
EP0507094A3 (en) Nematic liquid-crystal composition
CA2090577A1 (en) Antibiotic preparation and use of the same in plants
USD353895S (en) Window frame extrusion

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed