CA2085230A1 - Process for activating reproduction of seasonal breeding animals by administering l-dihydroxyphenylalanine (l-dopa) - Google Patents

Process for activating reproduction of seasonal breeding animals by administering l-dihydroxyphenylalanine (l-dopa)

Info

Publication number
CA2085230A1
CA2085230A1 CA002085230A CA2085230A CA2085230A1 CA 2085230 A1 CA2085230 A1 CA 2085230A1 CA 002085230 A CA002085230 A CA 002085230A CA 2085230 A CA2085230 A CA 2085230A CA 2085230 A1 CA2085230 A1 CA 2085230A1
Authority
CA
Canada
Prior art keywords
dopa
dihydroxyphenylalanine
administering
breeding animals
seasonal breeding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002085230A
Other languages
French (fr)
Other versions
CA2085230C (en
Inventor
Albert H. Meier
John M. Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Louisiana State University and Agricultural and Mechanical College
Original Assignee
Albert H. Meier
John M. Wilson
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College (The)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albert H. Meier, John M. Wilson, Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College (The) filed Critical Albert H. Meier
Publication of CA2085230A1 publication Critical patent/CA2085230A1/en
Application granted granted Critical
Publication of CA2085230C publication Critical patent/CA2085230C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate

Abstract

A process is provided for activating reproduction in seasonal breeding vertebrates during normally non-reproductive sea-sons by administering L-dihydroxyphenylalanine (L-DOPA), thereby increasing the level of L-DOPA in the vertebrate's blood-stream to a reproductively active level. An effective amount of 5-HTP can also be injected into the vertebrate followed, an effec-tive period of time later, with an injection of an effective amount of L-DOPA.
CA002085230A 1990-06-13 1991-06-11 Process for activating reproduction of seasonal breeding animals by administering l-dihydroxyphenylalanine (l-dopa) Expired - Fee Related CA2085230C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53853890A 1990-06-13 1990-06-13
US538,538 1990-06-13
PCT/US1991/004115 WO1991019492A1 (en) 1990-06-13 1991-06-11 Process for activating reproduction of seasonal breeding animals by administering l-dihydroxyphenylalanine (l-dopa)

Publications (2)

Publication Number Publication Date
CA2085230A1 true CA2085230A1 (en) 1991-12-14
CA2085230C CA2085230C (en) 2003-09-09

Family

ID=24147325

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002085230A Expired - Fee Related CA2085230C (en) 1990-06-13 1991-06-11 Process for activating reproduction of seasonal breeding animals by administering l-dihydroxyphenylalanine (l-dopa)

Country Status (8)

Country Link
US (1) US5650438A (en)
EP (1) EP0533818B1 (en)
AU (1) AU8076691A (en)
CA (1) CA2085230C (en)
DE (1) DE69128474T2 (en)
HU (1) HUT63327A (en)
MX (1) MX174225B (en)
WO (1) WO1991019492A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665375A (en) * 1995-05-31 1997-09-09 Board Of Supervisors Of Louisiana University And Agricultural And Mechanical College Method of altering the contents of eggs
US6759437B2 (en) * 1999-10-04 2004-07-06 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity including cysteine
US6403657B1 (en) * 1999-10-04 2002-06-11 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity
US20090311795A1 (en) * 2002-03-21 2009-12-17 Hinz Martin C Bilateral control of functions traditionally regulated by only serotonin or only dopamine
WO2003079886A2 (en) * 2002-03-21 2003-10-02 Hinz Martin C Serotonin and catecholamine system segment optimization techonology
US20070293571A1 (en) * 2006-06-08 2007-12-20 Hinz Martin C Adminstration of dopa precursors with sources of dopa to effectuate optimal catecholamine neurotransmitter outcomes
WO2004075724A2 (en) * 2003-02-21 2004-09-10 Hinz Martin C Serotonin and catecholamine system segment optimization technology
JP4638685B2 (en) * 2003-06-10 2011-02-23 ハイデルベルガー ドルツクマシーネン アクチエンゲゼルシヤフト Method of metering dampening water during printing on an offset press

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3462536A (en) * 1960-07-22 1969-08-19 Merck & Co Inc Method of inhibiting decarboxylase
GB1518726A (en) * 1975-11-04 1978-07-26 Sankyo Co Method of enhancing reproductive efficiency in nonhuman animals
US4241082A (en) * 1977-09-02 1980-12-23 Sankyo Company Limited Agents for promoting reproductive ability of domestic animals

Also Published As

Publication number Publication date
HUT63327A (en) 1993-08-30
HU9203903D0 (en) 1993-03-29
EP0533818B1 (en) 1997-12-17
WO1991019492A1 (en) 1991-12-26
EP0533818A4 (en) 1993-05-05
DE69128474D1 (en) 1998-01-29
MX174225B (en) 1994-04-27
US5650438A (en) 1997-07-22
CA2085230C (en) 2003-09-09
AU8076691A (en) 1992-01-07
EP0533818A1 (en) 1993-03-31
DE69128474T2 (en) 1998-04-09

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Legal Events

Date Code Title Description
EEER Examination request
MKLC Lapsed (correction)
MKLA Lapsed