CA2072885A1 - Polarographic chemical sensor with external reference electrode - Google Patents

Polarographic chemical sensor with external reference electrode

Info

Publication number
CA2072885A1
CA2072885A1 CA2072885A CA2072885A CA2072885A1 CA 2072885 A1 CA2072885 A1 CA 2072885A1 CA 2072885 A CA2072885 A CA 2072885A CA 2072885 A CA2072885 A CA 2072885A CA 2072885 A1 CA2072885 A1 CA 2072885A1
Authority
CA
Canada
Prior art keywords
membrane
reference electrode
polarographic
external reference
chemical sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2072885A
Other languages
French (fr)
Other versions
CA2072885C (en
Inventor
Bruce Burgess
Mark Meyerhoff
Peter H. Burleigh
John Ellison
Christine A. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IL SENSOR SYSTEMS Inc
Original Assignee
Il Sensor Systems, Inc.
Bruce Burgess
Mark Meyerhoff
Peter H. Burleigh
John Ellison
Christine A. Smith
Mallinckrodt Sensor Systems, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Il Sensor Systems, Inc., Bruce Burgess, Mark Meyerhoff, Peter H. Burleigh, John Ellison, Christine A. Smith, Mallinckrodt Sensor Systems, Inc. filed Critical Il Sensor Systems, Inc.
Publication of CA2072885A1 publication Critical patent/CA2072885A1/en
Application granted granted Critical
Publication of CA2072885C publication Critical patent/CA2072885C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Abstract

An electroanalytical electrode assembly comprises an electrically conductive working electrode which includes an electrical conductor (15) having a body of electrolyte material (16) thereupon and separated from the analytical environment by a hydrophobic membrane (18). The membrane has an electrical conductivity greater than the electrical conductivity of the remainder of the measuring circuit and is selectably permeable for a preselected and ionic species, so as to provide a stable membrane potential.
Use of an assembly of this type allows for placement of a reference electrode (20) external of the membrane (18).
CA002072885A 1990-01-22 1991-01-22 Polarographic chemical sensor with external reference electrode Expired - Fee Related CA2072885C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/468,277 US5078854A (en) 1990-01-22 1990-01-22 Polarographic chemical sensor with external reference electrode
US468,277 1990-01-22

Publications (2)

Publication Number Publication Date
CA2072885A1 true CA2072885A1 (en) 1991-07-23
CA2072885C CA2072885C (en) 1997-12-16

Family

ID=23859161

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002072885A Expired - Fee Related CA2072885C (en) 1990-01-22 1991-01-22 Polarographic chemical sensor with external reference electrode

Country Status (6)

Country Link
US (1) US5078854A (en)
EP (1) EP0512053A4 (en)
JP (1) JPH05503580A (en)
AU (1) AU638111B2 (en)
CA (1) CA2072885C (en)
WO (1) WO1991010900A1 (en)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221456A (en) * 1991-10-22 1993-06-22 Rosemount Inc. Insulated core electrode for ph sensor
US5571396A (en) * 1993-07-12 1996-11-05 Dade International Inc. Fluid analysis system and sensing electrode, electrode assembly, and sensing module components
GB9402661D0 (en) * 1994-02-11 1994-04-06 Ecossensors Ltd Improvements in and relating to detection of lead in blood
NO951705D0 (en) * 1995-05-03 1995-05-03 Sinvent As All-solid state reference electrode
WO1997043634A1 (en) * 1996-05-16 1997-11-20 Sendx Medical, Inc. Sensors with subminiature through holes, and method for fabricating such sensors
US5858452A (en) * 1996-05-16 1999-01-12 Sendx Medical, Inc. Method for fabricating wiring substrate with subminiature thru-holes
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
ATE227844T1 (en) * 1997-02-06 2002-11-15 Therasense Inc SMALL VOLUME SENSOR FOR IN-VITRO DETERMINATION
US9066695B2 (en) * 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) * 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) * 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6251260B1 (en) 1998-08-24 2001-06-26 Therasense, Inc. Potentiometric sensors for analytic determination
US6338790B1 (en) * 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) * 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6416651B1 (en) * 1999-02-26 2002-07-09 Honeywell Measurex Multi-electrode composition measuring device and method
EP1192269A2 (en) 1999-06-18 2002-04-03 Therasense, Inc. MASS TRANSPORT LIMITED i IN VIVO /i ANALYTE SENSOR
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
US20060091006A1 (en) * 1999-11-04 2006-05-04 Yi Wang Analyte sensor with insertion monitor, and methods
GB0027487D0 (en) 2000-11-10 2000-12-27 Univ Cranfield Home hygiene indicator
US6560471B1 (en) * 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
WO2002078512A2 (en) * 2001-04-02 2002-10-10 Therasense, Inc. Blood glucose tracking apparatus and methods
US6872297B2 (en) * 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US7842234B2 (en) * 2002-12-02 2010-11-30 Epocal Inc. Diagnostic devices incorporating fluidics and methods of manufacture
US7767068B2 (en) * 2002-12-02 2010-08-03 Epocal Inc. Heterogeneous membrane electrodes
US7094330B2 (en) * 2002-12-02 2006-08-22 Epocal Inc. Heterogeneous membrane electrodes
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US7587287B2 (en) * 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US8187446B2 (en) * 2003-06-17 2012-05-29 Chun-Mu Huang Method of manufacturing a disposable electrochemical sensor strip
US7306641B2 (en) * 2003-09-12 2007-12-11 Hewlett-Packard Development Company, L.P. Integral fuel cartridge and filter
EP1718198A4 (en) 2004-02-17 2008-06-04 Therasense Inc Method and system for providing data communication in continuous glucose monitoring and management system
US8112240B2 (en) * 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US20090054747A1 (en) * 2005-10-31 2009-02-26 Abbott Diabetes Care, Inc. Method and system for providing analyte sensor tester isolation
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US20090054749A1 (en) * 2006-05-31 2009-02-26 Abbott Diabetes Care, Inc. Method and System for Providing Data Transmission in a Data Management System
US7920907B2 (en) * 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
US7736478B2 (en) * 2006-09-06 2010-06-15 Chung Yuan Christian University Ion solution concentration-detecting device
US20080182136A1 (en) * 2007-01-26 2008-07-31 Arnold Don W Microscale Electrochemical Cell And Methods Incorporating The Cell
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) * 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20080281179A1 (en) * 2007-05-08 2008-11-13 Abbott Diabetes Care, Inc. Analyte monitoring system and methods
US8103456B2 (en) * 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US20100213057A1 (en) * 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
WO2010127050A1 (en) * 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
JP2011018635A (en) * 2009-06-08 2011-01-27 Sony Corp Fuel cell, process for manufacture of fuel cell, electronic device, enzyme-immobilized electrode, biosensor, energy conversion element, cell, cell organelle, and bacterium
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
EP2482720A4 (en) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc Method and apparatus for providing notification function in analyte monitoring systems
US20130123594A1 (en) * 2010-03-09 2013-05-16 Arkray, Inc. Electrochemical Sensor
CN101923067B (en) * 2010-04-15 2014-03-12 许建民 Polarographic flow-through cell
EP2775918B1 (en) 2011-11-07 2020-02-12 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
AU2015226950B2 (en) * 2014-03-06 2019-10-31 Thomas A. Davis Methods and devices for measuring conductivity of fluids

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE374818B (en) * 1971-06-17 1975-03-17 M Sharp
CH559912A5 (en) * 1971-09-09 1975-03-14 Hoffmann La Roche
US3840452A (en) * 1972-06-23 1974-10-08 Corning Glass Works Electrode for measuring concentration of choline and its esters
GB1437091A (en) * 1972-10-02 1976-05-26 Radiometer As Calcium electrode and membrane and composition for use therein
US3948745A (en) * 1973-06-11 1976-04-06 The United States Of America As Represented By The Department Of Health, Education And Welfare Enzyme electrode
US3857777A (en) * 1973-08-10 1974-12-31 Environmental Protection Agenc Ion exchange membrane for measuring orthophosphate
US3957613A (en) * 1974-11-01 1976-05-18 General Electric Company Miniature probe having multifunctional electrodes for sensing ions and gases
DE2551004A1 (en) * 1975-11-13 1977-05-26 Owens Illinois Inc Determn. of glucose by oxidn. on supported glucose oxidase - and polarographic determn. of hydrogen peroxide formed, esp. for analysis of blood serum
DE2613355C3 (en) * 1976-03-29 1978-11-30 Siemens Ag, 1000 Berlin Und 8000 Muenchen Process for the manufacture of cathodes for polarographic measurements
US4168219A (en) * 1977-04-04 1979-09-18 Agency Of Industrial Science & Technology, Ministry Of International Trade & Industry Electrode for measurement of ionic activity, sensor film therefor and method for manufacture thereof
JPS5912135B2 (en) * 1977-09-28 1984-03-21 松下電器産業株式会社 enzyme electrode
US4172770A (en) * 1978-03-27 1979-10-30 Technicon Instruments Corporation Flow-through electrochemical system analytical method
DK230183D0 (en) * 1983-05-24 1983-05-24 Radiometer As ELECTRIC DEVICE FOR APPLICATION ON A SKIN SURFACE
US4654127A (en) * 1984-04-11 1987-03-31 Sentech Medical Corporation Self-calibrating single-use sensing device for clinical chemistry and method of use
CA1258496A (en) * 1984-07-30 1989-08-15 Teruyoshi Uchida Insulated noble metal wire and porous membrane as po.sub.2 bioelectrode
US4820399A (en) * 1984-08-31 1989-04-11 Shimadzu Corporation Enzyme electrodes
GB8529300D0 (en) * 1985-11-28 1986-01-02 Ici Plc Membrane
GB8622788D0 (en) * 1986-09-22 1986-10-29 Atomic Energy Authority Uk Sensor
US4818361A (en) * 1986-12-10 1989-04-04 Diamond Sensor Systems Combined pH and dissolved carbon dioxide gas sensor
US4871439A (en) * 1987-02-05 1989-10-03 Steven Enzer Disposable self-calibratable electrode package
AT392847B (en) * 1989-01-27 1991-06-25 Avl Verbrennungskraft Messtech SENSOR ELECTRODE ARRANGEMENT

Also Published As

Publication number Publication date
CA2072885C (en) 1997-12-16
EP0512053A1 (en) 1992-11-11
EP0512053A4 (en) 1995-11-22
AU7330391A (en) 1991-08-05
JPH05503580A (en) 1993-06-10
WO1991010900A1 (en) 1991-07-25
US5078854A (en) 1992-01-07
AU638111B2 (en) 1993-06-17

Similar Documents

Publication Publication Date Title
CA2072885A1 (en) Polarographic chemical sensor with external reference electrode
BR8603408A (en) PORTABLE ION GENERATOR
US4681115A (en) Electrochemical measuring cell having an ancillary electrode
US4583548A (en) Bioelectric electrode-arrangement
GB2311378A (en) NMR sample cell
BR9007697A (en) DRUMS
CA2387899A1 (en) Electrochemical gas sensor
KR920016848A (en) Solid Contact Surface System for Potentiometer Sensors
FR2470449B1 (en) ELECTROCHEMICAL CELL CONTAINING AN INSULATOR BETWEEN THE HOUSING AND THE ELECTRODE ASSEMBLY AND ITS MANUFACTURING METHOD
NO153376C (en) OXYGEN POLARIZED cathode and its use.
US4710848A (en) Solid state cell
AU508580B1 (en) Stable Electrode for Electrochemical Applications
AU3366093A (en) Reference electrodes
EP0300662A3 (en) Ion-selective electrodes
GB2004071A (en) Electrical conductivity sensor
JP2582658Y2 (en) Reference electrode
GB2020819A (en) Percutaneous Blood-Oxygen Concentration Measuring Sensor
JPS5497491A (en) Measuring method of enzyme activity
IE872514L (en) Ion selective electrodes
RU93021666A (en) ELECTRODE SYSTEM FOR VOLTAMPOMETRIC ANALYSIS
ES2009423A6 (en) Ion-selective electrode in mobile holder
DK421483A (en) Electrode arrangement
JPS6435531A (en) Conductive high-polymer electrochromic element
AU4898490A (en) Measurement of electrochemical potential in low electrical conductivity environment
ES456210A1 (en) A device to generate high potentials at the time of high current current in an electrochemical system. (Machine-translation by Google Translate, not legally binding)

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed