CA2050911A1 - Encapsulation process and products therefrom - Google Patents

Encapsulation process and products therefrom

Info

Publication number
CA2050911A1
CA2050911A1 CA2050911A CA2050911A CA2050911A1 CA 2050911 A1 CA2050911 A1 CA 2050911A1 CA 2050911 A CA2050911 A CA 2050911A CA 2050911 A CA2050911 A CA 2050911A CA 2050911 A1 CA2050911 A1 CA 2050911A1
Authority
CA
Canada
Prior art keywords
agent
effective amount
products therefrom
encapsulation process
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2050911A
Other languages
French (fr)
Other versions
CA2050911C (en
Inventor
Thomas R. Tice
Richard M. Gilley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Southern Research Institute
Original Assignee
Thomas R. Tice
Richard M. Gilley
Southern Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23363857&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2050911(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thomas R. Tice, Richard M. Gilley, Southern Research Institute filed Critical Thomas R. Tice
Publication of CA2050911A1 publication Critical patent/CA2050911A1/en
Application granted granted Critical
Publication of CA2050911C publication Critical patent/CA2050911C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Abstract

A method of microencapsulating an agent to form a microencapsulated product, having the steps of dispersing an effective amount of the agent in a solvent containing a dissolved wall forming material to form a dispersion, combining the dispersion with an effective amount of a continuous process medium to form an emulsion that contains the process medium and microdroplets having the agent, the solvent and the wall forming material and adding rapidly the emulsion to an effective amount of an extraction medium to extract the solvent from the microdroplets to form the microencapsulated product.
CA002050911A 1989-05-04 1990-05-02 Encapsulation process and products therefrom Expired - Lifetime CA2050911C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34747689A 1989-05-04 1989-05-04
US347,476 1989-05-04

Publications (2)

Publication Number Publication Date
CA2050911A1 true CA2050911A1 (en) 1990-11-05
CA2050911C CA2050911C (en) 1997-07-15

Family

ID=23363857

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002050911A Expired - Lifetime CA2050911C (en) 1989-05-04 1990-05-02 Encapsulation process and products therefrom

Country Status (21)

Country Link
US (1) US5407609A (en)
EP (1) EP0471036B2 (en)
JP (1) JP2582186B2 (en)
KR (1) KR0162660B1 (en)
CN (1) CN1047223A (en)
AT (1) ATE133087T1 (en)
AU (1) AU5741590A (en)
CA (1) CA2050911C (en)
DE (1) DE69024953T3 (en)
DK (1) DK0471036T4 (en)
ES (1) ES2084698T5 (en)
FI (1) FI103183B1 (en)
GR (1) GR1000614B (en)
HK (1) HK30897A (en)
IE (1) IE69313B1 (en)
IL (1) IL94296A (en)
MX (1) MX20594A (en)
NO (1) NO302683B1 (en)
NZ (1) NZ233570A (en)
WO (1) WO1990013361A1 (en)
ZA (1) ZA903411B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017085508A1 (en) 2015-11-19 2017-05-26 Sofia University "St. Kliment Ohridski" A method for the preparation of particles with controlled shape and/or size

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* Cited by examiner, † Cited by third party
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GR900100330A (en) 1991-10-10
NO914292L (en) 1991-11-01
ES2084698T5 (en) 2005-03-01
ZA903411B (en) 1991-02-27
DE69024953T3 (en) 2005-01-27
DK0471036T4 (en) 2004-07-19
CA2050911C (en) 1997-07-15
EP0471036B2 (en) 2004-06-23
NO302683B1 (en) 1998-04-14
EP0471036B1 (en) 1996-01-17
FI103183B (en) 1999-05-14
FI915129A0 (en) 1991-10-30
HK30897A (en) 1997-03-21
FI103183B1 (en) 1999-05-14
US5407609A (en) 1995-04-18
NZ233570A (en) 1992-12-23
IL94296A (en) 1995-10-31
DE69024953T2 (en) 1996-08-14

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