CA2042373A1 - System for monitoring and controlling blood glucose - Google Patents

System for monitoring and controlling blood glucose

Info

Publication number
CA2042373A1
CA2042373A1 CA2042373A CA2042373A CA2042373A1 CA 2042373 A1 CA2042373 A1 CA 2042373A1 CA 2042373 A CA2042373 A CA 2042373A CA 2042373 A CA2042373 A CA 2042373A CA 2042373 A1 CA2042373 A1 CA 2042373A1
Authority
CA
Canada
Prior art keywords
blood glucose
disclosed
monitoring
glucose
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2042373A
Other languages
French (fr)
Other versions
CA2042373C (en
Inventor
Yoram Palti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carmel Biosensors Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2042373A1 publication Critical patent/CA2042373A1/en
Application granted granted Critical
Publication of CA2042373C publication Critical patent/CA2042373C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0017Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system transmitting optical signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031Implanted circuitry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Emergency Medicine (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Systems are disclosed which utilize implanted glucose sensitive living cells to monitor blood glucose levels. The implanted cells produce a detectable electrical or optical signal in response to changes in glucose concentration in surrounding tissue. The signal is then detected and interpreted to give a reading indicative o~ blood glucose levels. Capsules containing glucose sensitive cells and electrodes for detecting electrical activity are also disclosed. Methods of monitoring blood glucose are also described utilizing the systems and capsules disclosed.
CA002042373A 1989-08-11 1990-08-13 System for monitoring and controlling blood glucose Expired - Fee Related CA2042373C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US392,828 1989-08-11
US07/392,828 US5101814A (en) 1989-08-11 1989-08-11 System for monitoring and controlling blood glucose
PCT/US1990/004549 WO1991001680A1 (en) 1989-08-11 1990-08-13 System for monitoring and controlling blood glucose

Publications (2)

Publication Number Publication Date
CA2042373A1 true CA2042373A1 (en) 1991-02-12
CA2042373C CA2042373C (en) 1999-11-16

Family

ID=23552156

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002042373A Expired - Fee Related CA2042373C (en) 1989-08-11 1990-08-13 System for monitoring and controlling blood glucose

Country Status (6)

Country Link
US (2) US5101814A (en)
EP (1) EP0461207B1 (en)
AT (1) ATE134120T1 (en)
CA (1) CA2042373C (en)
DE (1) DE69025400T2 (en)
WO (1) WO1991001680A1 (en)

Families Citing this family (528)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066847A (en) * 1989-01-19 2000-05-23 Futrex Inc. Procedure for verifying the accuracy of non-invasive blood glucose measurement instruments
US5101814A (en) * 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US6040194A (en) * 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5251126A (en) * 1990-10-29 1993-10-05 Miles Inc. Diabetes data analysis and interpretation method
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
JPH04278450A (en) 1991-03-04 1992-10-05 Adam Heller Biosensor and method for analyzing subject
US5865728A (en) * 1991-05-29 1999-02-02 Origin Medsystems, Inc. Method of using an endoscopic inflatable lifting apparatus to create an anatomic working space
US5239998A (en) * 1991-07-18 1993-08-31 The United States Of America As Represented By The Department Of Health And Human Services Apparatus and method for fluorescent excitation and detection from potentiometric dyes with a single-ended optical fiber
NL9200207A (en) * 1992-02-05 1993-09-01 Nedap Nv IMPLANTABLE BIOMEDICAL SENSOR DEVICE, IN PARTICULAR FOR MEASUREMENT OF THE GLUCOSE CONCENTRATION.
US5376070A (en) * 1992-09-29 1994-12-27 Minimed Inc. Data transfer system for an infusion pump
US5956501A (en) * 1997-01-10 1999-09-21 Health Hero Network, Inc. Disease simulation system and method
US5341805A (en) * 1993-04-06 1994-08-30 Cedars-Sinai Medical Center Glucose fluorescence monitor and method
US5569186A (en) * 1994-04-25 1996-10-29 Minimed Inc. Closed loop infusion pump system with removable glucose sensor
US5529066A (en) * 1994-06-27 1996-06-25 Cb-Carmel Biotechnology Ltd. Implantable capsule for enhancing cell electric signals
US5474552A (en) * 1994-06-27 1995-12-12 Cb-Carmel Biotechnology Ltd. Implantable drug delivery pump
US5513636A (en) * 1994-08-12 1996-05-07 Cb-Carmel Biotechnology Ltd. Implantable sensor chip
US5752512A (en) * 1995-05-10 1998-05-19 Massachusetts Institute Of Technology Apparatus and method for non-invasive blood analyte measurement
US5628310A (en) * 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
US5665065A (en) * 1995-05-26 1997-09-09 Minimed Inc. Medication infusion device with blood glucose data input
US5995860A (en) * 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
AU1058297A (en) 1995-11-22 1997-06-11 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
US6002954A (en) * 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
US8825152B2 (en) 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
JP4175662B2 (en) 1996-01-08 2008-11-05 インパルス ダイナミクス エヌ.ヴイ. Electric muscle control device
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
US7167748B2 (en) 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
US8321013B2 (en) * 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
US9713723B2 (en) 1996-01-11 2017-07-25 Impulse Dynamics Nv Signal delivery through the right ventricular septum
DE19621770C1 (en) * 1996-05-30 1998-01-02 Siemens Ag Implantable insulin pump
JP2000515778A (en) * 1996-07-08 2000-11-28 アニマス コーポレーシヨン Implantable sensors and systems for in vivo measurement and control of body fluid component levels
WO1998022820A1 (en) 1996-11-21 1998-05-28 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
US5846188A (en) 1997-01-17 1998-12-08 Palti; Yoram Sensor utilizing living muscle cells
WO1998035225A1 (en) 1997-02-06 1998-08-13 E. Heller & Company Small volume in vitro analyte sensor
US6862465B2 (en) * 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US7657297B2 (en) 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US6741877B1 (en) * 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US7192450B2 (en) * 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US7885697B2 (en) 2004-07-13 2011-02-08 Dexcom, Inc. Transcutaneous analyte sensor
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US5919216A (en) * 1997-06-16 1999-07-06 Medtronic, Inc. System and method for enhancement of glucose production by stimulation of pancreatic beta cells
US6093167A (en) * 1997-06-16 2000-07-25 Medtronic, Inc. System for pancreatic stimulation and glucose measurement
US6579690B1 (en) * 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
US6103033A (en) 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
GB2335496B (en) * 1998-03-20 2000-06-07 David Eglise Sensing devices & systems
GB9805896D0 (en) 1998-03-20 1998-05-13 Eglise David Remote analysis system
US6505059B1 (en) 1998-04-06 2003-01-07 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US20020091324A1 (en) * 1998-04-06 2002-07-11 Nikiforos Kollias Non-invasive tissue glucose level monitoring
US7899518B2 (en) * 1998-04-06 2011-03-01 Masimo Laboratories, Inc. Non-invasive tissue glucose level monitoring
US6728560B2 (en) 1998-04-06 2004-04-27 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US6721582B2 (en) 1999-04-06 2004-04-13 Argose, Inc. Non-invasive tissue glucose level monitoring
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6045513A (en) * 1998-05-13 2000-04-04 Medtronic, Inc. Implantable medical device for tracking patient functional status
DE69934687T2 (en) * 1998-05-28 2007-10-18 Carmel Biosensors Ltd. FREQUENCY ESTIMATION IN ELECTRO-ISLET-GRAPHIE
US6884215B1 (en) 1998-05-28 2005-04-26 Carmel Biosensors Ltd. Frequency estimation of electro-islet-graphy
US6251260B1 (en) 1998-08-24 2001-06-26 Therasense, Inc. Potentiometric sensors for analytic determination
US6949081B1 (en) * 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
EP1107690B1 (en) 1998-09-04 2003-04-16 PowderJect Research Limited Second medical use of a particle delivery method
US6602678B2 (en) 1998-09-04 2003-08-05 Powderject Research Limited Non- or minimally invasive monitoring methods
US6844166B1 (en) 1998-09-11 2005-01-18 Sensor Technologies Inc. Recombinant reduced valency carbohydrate binding ligands
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
CA2666429A1 (en) * 1998-10-08 2000-04-13 Medtronic Minimed, Inc. Telemetered characteristic monitor system
US7621893B2 (en) 1998-10-29 2009-11-24 Medtronic Minimed, Inc. Methods and apparatuses for detecting occlusions in an ambulatory infusion pump
US7766873B2 (en) 1998-10-29 2010-08-03 Medtronic Minimed, Inc. Method and apparatus for detecting occlusions in an ambulatory infusion pump
AU1623300A (en) * 1998-11-13 2000-06-05 Sensor Technologies, Inc. Monodisperse preparations useful with implanted devices
DE69924749T2 (en) * 1998-11-20 2006-04-27 The University Of Connecticut, Farmington Generically integrated implantable potentiostat remote sensing device for electrochemical probes
US6821738B2 (en) * 1999-01-20 2004-11-23 The Board Of Regents For Oklahoma State University Broad spectrum bio-detection of nerve agents, organophosphates, and other chemical warfare agents
MXPA01007820A (en) * 1999-02-04 2003-06-19 Technion Res & Dev Foundation Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells.
WO2001091854A1 (en) 2000-05-31 2001-12-06 Impulse Dynamics Nv Electropancreatography
US20040249421A1 (en) * 2000-09-13 2004-12-09 Impulse Dynamics Nv Blood glucose level control
US8700161B2 (en) 1999-03-05 2014-04-15 Metacure Limited Blood glucose level control
US8019421B2 (en) * 1999-03-05 2011-09-13 Metacure Limited Blood glucose level control
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8666495B2 (en) 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US6669663B1 (en) * 1999-04-30 2003-12-30 Medtronic, Inc. Closed loop medicament pump
US7806886B2 (en) * 1999-06-03 2010-10-05 Medtronic Minimed, Inc. Apparatus and method for controlling insulin infusion with state variable feedback
US6654625B1 (en) 1999-06-18 2003-11-25 Therasense, Inc. Mass transport limited in vivo analyte sensor
US6682938B1 (en) 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
US6673625B2 (en) 1999-09-15 2004-01-06 The Regents Of The University Of California Saccharide sensing molecules having enhanced fluorescent properties
US6216022B1 (en) 2000-06-22 2001-04-10 Biosafe Laboratories, Inc. Implantable optical measurement device and method for using same
US6361522B1 (en) * 1999-10-21 2002-03-26 Cardiac Pacemakers, Inc. Drug delivery system for implantable cardiac device
US20060091006A1 (en) * 1999-11-04 2006-05-04 Yi Wang Analyte sensor with insertion monitor, and methods
US6616819B1 (en) * 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
IL134009A (en) 2000-01-12 2011-07-31 Bo2 Technologies Ltd Implantable device
US8012500B2 (en) * 2000-01-01 2011-09-06 Beta-O2 Technologies Ltd. Implantable device
US6600953B2 (en) * 2000-12-11 2003-07-29 Impulse Dynamics N.V. Acute and chronic electrical signal therapy for obesity
US20030060765A1 (en) * 2000-02-16 2003-03-27 Arthur Campbell Infusion device menu structure and method of using the same
ATE499988T1 (en) 2000-03-02 2011-03-15 Microchips Inc MICROMECHANICAL DEVICES AND METHODS FOR STORAGE AND SELECTIVE EXPOSURE OF CHEMICALS
DE10011284B4 (en) * 2000-03-08 2007-06-28 Disetronic Licensing Ag Apparatus for in vivo measurement of the concentration of an ingredient of a body fluid
WO2001082784A2 (en) * 2000-05-03 2001-11-08 Cornell Research Foundation, Inc. Enhanced biologically based chronotropic biosensing
US6605039B2 (en) 2000-07-24 2003-08-12 Medtronic, Inc. Cell-based biosensors suitable for implantable medical device applications
US6549861B1 (en) 2000-08-10 2003-04-15 Euro-Celtique, S.A. Automated system and method for spectroscopic analysis
EP1311189A4 (en) 2000-08-21 2005-03-09 Euro Celtique Sa Near infrared blood glucose monitoring system
GB0025147D0 (en) * 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
US7369890B2 (en) 2000-11-02 2008-05-06 Cardiac Pacemakers, Inc. Technique for discriminating between coordinated and uncoordinated cardiac rhythms
US6689117B2 (en) 2000-12-18 2004-02-10 Cardiac Pacemakers, Inc. Drug delivery system for implantable medical device
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
EP1357971B1 (en) * 2001-01-05 2015-05-20 Metacure Limited Regulation of eating habits
CA2432438C (en) 2001-01-09 2011-04-26 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
US6927246B2 (en) * 2001-02-15 2005-08-09 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs and methods for making them
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
CN1270667C (en) * 2001-04-18 2006-08-23 超治疗股份有限公司 Analysis of eating habits
EP2140891B1 (en) 2001-05-18 2013-03-27 DEKA Products Limited Partnership Conduit for coupling to a fluid delivery device
US8034026B2 (en) * 2001-05-18 2011-10-11 Deka Products Limited Partnership Infusion pump assembly
US7209783B2 (en) * 2001-06-15 2007-04-24 Cardiac Pacemakers, Inc. Ablation stent for treating atrial fibrillation
US7493162B2 (en) 2001-06-15 2009-02-17 Cardiac Pacemakers, Inc. Pulmonary vein stent for treating atrial fibrillation
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) * 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US6740072B2 (en) * 2001-09-07 2004-05-25 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US8152789B2 (en) * 2001-10-23 2012-04-10 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US6827702B2 (en) * 2001-09-07 2004-12-07 Medtronic Minimed, Inc. Safety limits for closed-loop infusion pump control
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
US7340303B2 (en) 2001-09-25 2008-03-04 Cardiac Pacemakers, Inc. Evoked response sensing for ischemia detection
US7096053B2 (en) * 2001-10-02 2006-08-22 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
US20070060812A1 (en) * 2001-11-29 2007-03-15 Metacure N.V. Sensing of pancreatic electrical activity
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US10022078B2 (en) 2004-07-13 2018-07-17 Dexcom, Inc. Analyte sensor
US7236821B2 (en) * 2002-02-19 2007-06-26 Cardiac Pacemakers, Inc. Chronically-implanted device for sensing and therapy
US7039462B2 (en) * 2002-06-14 2006-05-02 Cardiac Pacemakers, Inc. Method and apparatus for detecting oscillations in cardiac rhythm
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US20060258761A1 (en) * 2002-05-22 2006-11-16 Robert Boock Silicone based membranes for use in implantable glucose sensors
US7089055B2 (en) * 2002-06-28 2006-08-08 Cardiac Pacemakers, Inc. Method and apparatus for delivering pre-shock defibrillation therapy
US20040068230A1 (en) * 2002-07-24 2004-04-08 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US8512276B2 (en) * 2002-07-24 2013-08-20 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US7278983B2 (en) * 2002-07-24 2007-10-09 Medtronic Minimed, Inc. Physiological monitoring device for controlling a medication infusion device
WO2006086578A1 (en) * 2002-10-02 2006-08-17 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
US7727181B2 (en) 2002-10-09 2010-06-01 Abbott Diabetes Care Inc. Fluid delivery device with autocalibration
US7993108B2 (en) 2002-10-09 2011-08-09 Abbott Diabetes Care Inc. Variable volume, shape memory actuated insulin dispensing pump
DE60336834D1 (en) 2002-10-09 2011-06-01 Abbott Diabetes Care Inc FUEL FEEDING DEVICE, SYSTEM AND METHOD
US7226414B2 (en) * 2002-10-09 2007-06-05 Biotex, Inc. Method and apparatus for analyte sensing
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US7072711B2 (en) 2002-11-12 2006-07-04 Cardiac Pacemakers, Inc. Implantable device for delivering cardiac drug therapy
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US20040122353A1 (en) * 2002-12-19 2004-06-24 Medtronic Minimed, Inc. Relay device for transferring information between a sensor system and a fluid delivery system
MXPA05006994A (en) * 2002-12-27 2005-10-18 Diobex Inc Compositions and methods for the prevention and control of insulin-induced hypoglycemia.
US7655618B2 (en) * 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
EP1578262A4 (en) 2002-12-31 2007-12-05 Therasense Inc Continuous glucose monitoring system and methods of use
US7166458B2 (en) * 2003-01-07 2007-01-23 Bio Tex, Inc. Assay and method for analyte sensing by detecting efficiency of radiation conversion
US7372455B2 (en) * 2003-02-10 2008-05-13 N-Trig Ltd. Touch detection for a digitizer
WO2004080533A1 (en) * 2003-03-10 2004-09-23 Impulse Dynamics Nv Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue
US11439815B2 (en) 2003-03-10 2022-09-13 Impulse Dynamics Nv Protein activity modification
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US7679407B2 (en) 2003-04-28 2010-03-16 Abbott Diabetes Care Inc. Method and apparatus for providing peak detection circuitry for data communication systems
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US20040259270A1 (en) * 2003-06-19 2004-12-23 Wolf David E. System, device and method for exciting a sensor and detecting analyte
EP1641522B1 (en) * 2003-06-20 2012-12-19 Metacure Limited Gastrointestinal apparatus for detecting a change in posture
US7356365B2 (en) * 2003-07-09 2008-04-08 Glucolight Corporation Method and apparatus for tissue oximetry
US8792985B2 (en) 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US20070060971A1 (en) * 2003-07-21 2007-03-15 Ofer Glasberg Hepatic device for treatment or glucose detection
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US20050056552A1 (en) * 2003-07-25 2005-03-17 Simpson Peter C. Increasing bias for oxygen production in an electrode system
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US20100168657A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US6931327B2 (en) 2003-08-01 2005-08-16 Dexcom, Inc. System and methods for processing analyte sensor data
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7925321B2 (en) 2003-08-01 2011-04-12 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7236812B1 (en) 2003-09-02 2007-06-26 Biotex, Inc. System, device and method for determining the concentration of an analyte
US7306641B2 (en) * 2003-09-12 2007-12-11 Hewlett-Packard Development Company, L.P. Integral fuel cartridge and filter
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
USD902408S1 (en) 2003-11-05 2020-11-17 Abbott Diabetes Care Inc. Analyte sensor control unit
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
EP2239566B1 (en) 2003-12-05 2014-04-23 DexCom, Inc. Calibration techniques for a continuous analyte sensor
US8774886B2 (en) 2006-10-04 2014-07-08 Dexcom, Inc. Analyte sensor
US8287453B2 (en) 2003-12-05 2012-10-16 Dexcom, Inc. Analyte sensor
WO2005057175A2 (en) 2003-12-09 2005-06-23 Dexcom, Inc. Signal processing for continuous analyte sensor
US7510849B2 (en) * 2004-01-29 2009-03-31 Glucolight Corporation OCT based method for diagnosis and therapy
CA2556331A1 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
US8808228B2 (en) * 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
AU2005220794A1 (en) * 2004-03-06 2005-09-22 Calisto Medical, Inc. Methods and devices for non-invasively measuring quantitative information of substances in living organisms
US8548583B2 (en) 2004-03-10 2013-10-01 Impulse Dynamics Nv Protein activity modification
US11779768B2 (en) 2004-03-10 2023-10-10 Impulse Dynamics Nv Protein activity modification
US8352031B2 (en) * 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US20050261561A1 (en) * 2004-05-24 2005-11-24 Christopher W. Jones Blood testing and therapeutic compound delivery system
SI1759536T1 (en) 2004-06-01 2011-09-30 Kwalata Trading Ltd In vitro techniques for use with stem cells
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
DE202004009224U1 (en) * 2004-06-14 2004-08-12 Isra Vision Systems Ag Sensor for measuring the surface of an object
US20070100222A1 (en) * 2004-06-14 2007-05-03 Metronic Minimed, Inc. Analyte sensing apparatus for hospital use
US20060016700A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US7857760B2 (en) * 2004-07-13 2010-12-28 Dexcom, Inc. Analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
EP1786834B1 (en) * 2004-07-14 2016-02-17 Glusense Ltd. Implantable power sources and sensors
US7344500B2 (en) 2004-07-27 2008-03-18 Medtronic Minimed, Inc. Sensing system with auxiliary display
US8036727B2 (en) 2004-08-11 2011-10-11 Glt Acquisition Corp. Methods for noninvasively measuring analyte levels in a subject
US7254429B2 (en) * 2004-08-11 2007-08-07 Glucolight Corporation Method and apparatus for monitoring glucose levels in a biological tissue
WO2006018851A2 (en) * 2004-08-18 2006-02-23 Metacure Ltd. Monitoring, analysis, and regulation of eating habits
US7567841B2 (en) 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
EP1794585A1 (en) * 2004-08-31 2007-06-13 Lifescan Scotland Ltd Method of manufacturing an auto-calibrating sensor
US7303543B1 (en) * 2004-12-03 2007-12-04 Medtronic Minimed, Inc. Medication infusion set
EP1827571B1 (en) * 2004-12-09 2016-09-07 Impulse Dynamics NV Protein activity modification
JP2008524496A (en) * 2004-12-16 2008-07-10 インディペンデント ナチュラル リソーシーズ, インコーポレイテッド Buoyancy pump power system
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8571624B2 (en) * 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US20110060196A1 (en) * 2009-08-31 2011-03-10 Abbott Diabetes Care Inc. Flexible Mounting Unit and Cover for a Medical Device
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US8613703B2 (en) 2007-05-31 2013-12-24 Abbott Diabetes Care Inc. Insertion devices and methods
US7704229B2 (en) * 2005-02-03 2010-04-27 Medtronic Minimed, Inc. Insertion device
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US20060184104A1 (en) * 2005-02-15 2006-08-17 Medtronic Minimed, Inc. Needle guard
US9821158B2 (en) 2005-02-17 2017-11-21 Metacure Limited Non-immediate effects of therapy
US20060247154A1 (en) * 2005-02-24 2006-11-02 Lifescan, Inc. Concanavalin a, methods of expressing, purifying and characterizing concanavalina, and sensors including the same
US20070207498A1 (en) * 2005-02-24 2007-09-06 Lifescan, Inc. Design and construction of dimeric concanavalin a mutants
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
WO2006097934A2 (en) 2005-03-18 2006-09-21 Metacure Limited Pancreas lead
CN101180093B (en) 2005-03-21 2012-07-18 雅培糖尿病护理公司 Method and system for providing integrated medication infusion and analyte monitoring system
WO2007080595A2 (en) * 2006-01-12 2007-07-19 Metacure N.V. Electrode assemblies, tools, and methods for gastric wall implantation
WO2006110859A2 (en) 2005-04-13 2006-10-19 Glucolight Corporation Method for data reduction and calibration of an oct-based blood glucose monitor
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US7768408B2 (en) 2005-05-17 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing data management in data monitoring system
US8301256B2 (en) * 2005-06-02 2012-10-30 Metacure Limited GI lead implantation
US20060272652A1 (en) * 2005-06-03 2006-12-07 Medtronic Minimed, Inc. Virtual patient software system for educating and treating individuals with diabetes
US7620437B2 (en) 2005-06-03 2009-11-17 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US20070033074A1 (en) * 2005-06-03 2007-02-08 Medtronic Minimed, Inc. Therapy management system
US20070016449A1 (en) * 2005-06-29 2007-01-18 Gary Cohen Flexible glucose analysis using varying time report deltas and configurable glucose target ranges
US20070066956A1 (en) * 2005-07-27 2007-03-22 Medtronic Minimed, Inc. Systems and methods for entering temporary basal rate pattern in an infusion device
US20070060870A1 (en) * 2005-08-16 2007-03-15 Tolle Mike Charles V Controller device for an infusion pump
US7737581B2 (en) * 2005-08-16 2010-06-15 Medtronic Minimed, Inc. Method and apparatus for predicting end of battery life
US20090227855A1 (en) 2005-08-16 2009-09-10 Medtronic Minimed, Inc. Controller device for an infusion pump
US20070060869A1 (en) * 2005-08-16 2007-03-15 Tolle Mike C V Controller device for an infusion pump
US20070093786A1 (en) * 2005-08-16 2007-04-26 Medtronic Minimed, Inc. Watch controller for a medical device
US8005526B2 (en) * 2005-08-31 2011-08-23 The Regents Of The University Of Michigan Biologically integrated electrode devices
US9084546B2 (en) * 2005-08-31 2015-07-21 The Regents Of The University Of Michigan Co-electrodeposited hydrogel-conducting polymer electrodes for biomedical applications
US7713240B2 (en) 2005-09-13 2010-05-11 Medtronic Minimed, Inc. Modular external infusion device
US9072476B2 (en) 2005-09-23 2015-07-07 Medtronic Minimed, Inc. Flexible sensor apparatus
US7725148B2 (en) * 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes
US7756561B2 (en) 2005-09-30 2010-07-13 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US8442841B2 (en) 2005-10-20 2013-05-14 Matacure N.V. Patient selection method for assisting weight loss
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US7583190B2 (en) 2005-10-31 2009-09-01 Abbott Diabetes Care Inc. Method and apparatus for providing data communication in data monitoring and management systems
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
WO2007065095A2 (en) * 2005-11-29 2007-06-07 Spencer Rosero System and method for supporting a biological chip device
US8295932B2 (en) * 2005-12-05 2012-10-23 Metacure Limited Ingestible capsule for appetite regulation
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
CA2636034A1 (en) 2005-12-28 2007-10-25 Abbott Diabetes Care Inc. Medical device insertion
US7519409B2 (en) * 2005-12-29 2009-04-14 Medtronic, Inc. Implantable cell/tissue-based biosensing device
US7774038B2 (en) 2005-12-30 2010-08-10 Medtronic Minimed, Inc. Real-time self-calibrating sensor system and method
US7985330B2 (en) 2005-12-30 2011-07-26 Medtronic Minimed, Inc. Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy
US20070173712A1 (en) 2005-12-30 2007-07-26 Medtronic Minimed, Inc. Method of and system for stabilization of sensors
US20070169533A1 (en) * 2005-12-30 2007-07-26 Medtronic Minimed, Inc. Methods and systems for detecting the hydration of sensors
US8114268B2 (en) * 2005-12-30 2012-02-14 Medtronic Minimed, Inc. Method and system for remedying sensor malfunctions detected by electrochemical impedance spectroscopy
US8114269B2 (en) 2005-12-30 2012-02-14 Medtronic Minimed, Inc. System and method for determining the point of hydration and proper time to apply potential to a glucose sensor
US8344966B2 (en) 2006-01-31 2013-01-01 Abbott Diabetes Care Inc. Method and system for providing a fault tolerant display unit in an electronic device
US11364335B2 (en) 2006-02-09 2022-06-21 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US10010669B2 (en) 2006-02-09 2018-07-03 Deka Products Limited Partnership Systems and methods for fluid delivery
US11478623B2 (en) 2006-02-09 2022-10-25 Deka Products Limited Partnership Infusion pump assembly
US11027058B2 (en) 2006-02-09 2021-06-08 Deka Products Limited Partnership Infusion pump assembly
WO2007092637A2 (en) 2006-02-09 2007-08-16 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
US11497846B2 (en) 2006-02-09 2022-11-15 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
TW200734462A (en) 2006-03-08 2007-09-16 In Motion Invest Ltd Regulating stem cells
EP1991110B1 (en) 2006-03-09 2018-11-07 DexCom, Inc. Systems and methods for processing analyte sensor data
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US20070254381A1 (en) * 2006-04-27 2007-11-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Monitoring and/or treating syringe mechanism
US20070255125A1 (en) * 2006-04-28 2007-11-01 Moberg Sheldon B Monitor devices for networked fluid infusion systems
US20070254593A1 (en) * 2006-04-28 2007-11-01 Medtronic Minimed, Inc. Wireless data communication for a medical device network that supports a plurality of data communication modes
US20070255126A1 (en) * 2006-04-28 2007-11-01 Moberg Sheldon B Data communication in networked fluid infusion systems
US20070253380A1 (en) * 2006-04-28 2007-11-01 James Jollota Data translation device with nonvolatile memory for a networked medical device system
US8073008B2 (en) * 2006-04-28 2011-12-06 Medtronic Minimed, Inc. Subnetwork synchronization and variable transmit synchronization techniques for a wireless medical device network
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
GB0616566D0 (en) * 2006-08-19 2006-09-27 Rolls Royce Plc An alloy and method of treating titanium aluminide
US8936794B2 (en) * 2006-08-25 2015-01-20 The Regents Of The University Of Michigan Conducting polymer nanotube actuators for precisely controlled release of medicine and bioactive molecules
US8579853B2 (en) 2006-10-31 2013-11-12 Abbott Diabetes Care Inc. Infusion devices and methods
WO2008062417A2 (en) * 2006-11-22 2008-05-29 Beta O2 Technologies Ltd. Protecting algae from body fluids
EP2104492B1 (en) * 2006-11-28 2017-11-22 Beta O2 Technologies Ltd. Oxygen supply for cell transplant and vascularization
US20080139910A1 (en) * 2006-12-06 2008-06-12 Metronic Minimed, Inc. Analyte sensor and method of using the same
US10154804B2 (en) 2007-01-31 2018-12-18 Medtronic Minimed, Inc. Model predictive method and system for controlling and supervising insulin infusion
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US20080269714A1 (en) 2007-04-25 2008-10-30 Medtronic Minimed, Inc. Closed loop/semi-closed loop therapy modification system
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US20080300572A1 (en) * 2007-06-01 2008-12-04 Medtronic Minimed, Inc. Wireless monitor for a personal medical device system
CA2688184A1 (en) 2007-06-08 2008-12-18 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20080318314A1 (en) * 2007-06-20 2008-12-25 Valentin Fulga Production from blood of cells of neural lineage
US8821431B2 (en) 2007-09-07 2014-09-02 Beta O2 Technologies Ltd. Air gap for supporting cells
DE102007047351A1 (en) 2007-10-02 2009-04-09 B. Braun Melsungen Ag System and method for monitoring and controlling blood glucose levels
US9452258B2 (en) 2007-10-09 2016-09-27 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
US20090112626A1 (en) * 2007-10-30 2009-04-30 Cary Talbot Remote wireless monitoring, processing, and communication of patient data
US9839395B2 (en) 2007-12-17 2017-12-12 Dexcom, Inc. Systems and methods for processing sensor data
US8313467B2 (en) 2007-12-27 2012-11-20 Medtronic Minimed, Inc. Reservoir pressure equalization systems and methods
US10188787B2 (en) 2007-12-31 2019-01-29 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US8414563B2 (en) 2007-12-31 2013-04-09 Deka Products Limited Partnership Pump assembly with switch
CA3059311A1 (en) * 2007-12-31 2009-07-16 Deka Products Limited Partnership Wearable infusion pump assembly
US9456955B2 (en) 2007-12-31 2016-10-04 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US10080704B2 (en) 2007-12-31 2018-09-25 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US8900188B2 (en) 2007-12-31 2014-12-02 Deka Products Limited Partnership Split ring resonator antenna adapted for use in wirelessly controlled medical device
US8881774B2 (en) 2007-12-31 2014-11-11 Deka Research & Development Corp. Apparatus, system and method for fluid delivery
CA2715624A1 (en) * 2008-02-20 2009-08-27 Dexcom, Inc. Continuous medicament sensor system for in vivo use
CA2715628A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8571617B2 (en) 2008-03-04 2013-10-29 Glt Acquisition Corp. Flowometry in optical coherence tomography for analyte level estimation
US20090242399A1 (en) * 2008-03-25 2009-10-01 Dexcom, Inc. Analyte sensor
US20090292325A1 (en) * 2008-05-02 2009-11-26 Cederna Paul S Hybrid bioelectrical interface device
US8423130B2 (en) 2008-05-09 2013-04-16 Metacure Limited Optimization of thresholds for eating detection
US9295786B2 (en) 2008-05-28 2016-03-29 Medtronic Minimed, Inc. Needle protective device for subcutaneous sensors
WO2010032242A1 (en) * 2008-09-17 2010-03-25 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
US8223028B2 (en) 2008-10-10 2012-07-17 Deka Products Limited Partnership Occlusion detection system and method
US8066672B2 (en) 2008-10-10 2011-11-29 Deka Products Limited Partnership Infusion pump assembly with a backup power supply
US9180245B2 (en) 2008-10-10 2015-11-10 Deka Products Limited Partnership System and method for administering an infusible fluid
US8267892B2 (en) 2008-10-10 2012-09-18 Deka Products Limited Partnership Multi-language / multi-processor infusion pump assembly
US8016789B2 (en) 2008-10-10 2011-09-13 Deka Products Limited Partnership Pump assembly with a removable cover assembly
US8262616B2 (en) 2008-10-10 2012-09-11 Deka Products Limited Partnership Infusion pump assembly
US8708376B2 (en) 2008-10-10 2014-04-29 Deka Products Limited Partnership Medium connector
US8208973B2 (en) * 2008-11-05 2012-06-26 Medtronic Minimed, Inc. System and method for variable beacon timing with wireless devices
US9801575B2 (en) 2011-04-15 2017-10-31 Dexcom, Inc. Advanced analyte sensor calibration and error detection
US8043271B2 (en) * 2008-11-26 2011-10-25 Beta 02 Technologies Ltd. Apparatus for transportation of oxygen to implanted cells
US20100160740A1 (en) * 2008-12-24 2010-06-24 Gary Cohen Use of Patterns in a Therapy Management System
US20100161346A1 (en) * 2008-12-24 2010-06-24 Kristen Getschmann Systems and Methods for Providing Bolus Dosage Recommendations
US20100160749A1 (en) * 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
US9330237B2 (en) * 2008-12-24 2016-05-03 Medtronic Minimed, Inc. Pattern recognition and filtering in a therapy management system
US8126736B2 (en) 2009-01-23 2012-02-28 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8685093B2 (en) 2009-01-23 2014-04-01 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US8560082B2 (en) 2009-01-30 2013-10-15 Abbott Diabetes Care Inc. Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US8394246B2 (en) 2009-02-23 2013-03-12 Roche Diagnostics Operations, Inc. System and method for the electrochemical measurement of an analyte employing a remote sensor
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
US9446194B2 (en) * 2009-03-27 2016-09-20 Dexcom, Inc. Methods and systems for promoting glucose management
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US8467972B2 (en) 2009-04-28 2013-06-18 Abbott Diabetes Care Inc. Closed loop blood glucose control algorithm analysis
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
US9131885B2 (en) * 2009-07-02 2015-09-15 Dexcom, Inc. Analyte sensors and methods of manufacturing same
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
US8344847B2 (en) 2009-07-09 2013-01-01 Medtronic Minimed, Inc. Coordination of control commands in a medical device system having at least one therapy delivery device and at least one wireless controller device
US20110006880A1 (en) * 2009-07-09 2011-01-13 Medtronic Minimed, Inc. Fingerprint-linked control of a portable medical device
US20110009725A1 (en) * 2009-07-09 2011-01-13 Medtronic Minimed, Inc. Providing contextually relevant advertisements and e-commerce features in a personal medical device system
EP2453948B1 (en) 2009-07-15 2015-02-18 DEKA Products Limited Partnership Apparatus, systems and methods for an infusion pump assembly
DK3173014T3 (en) 2009-07-23 2021-09-13 Abbott Diabetes Care Inc Real-time control of data on physiological control of glucose levels
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
EP2473099A4 (en) 2009-08-31 2015-01-14 Abbott Diabetes Care Inc Analyte monitoring system and methods for managing power and noise
US8487758B2 (en) * 2009-09-02 2013-07-16 Medtronic Minimed, Inc. Medical device having an intelligent alerting scheme, and related operating methods
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
US8386042B2 (en) * 2009-11-03 2013-02-26 Medtronic Minimed, Inc. Omnidirectional accelerometer device and medical device incorporating same
US8574201B2 (en) 2009-12-22 2013-11-05 Medtronic Minimed, Inc. Syringe piston with check valve seal
US8755269B2 (en) * 2009-12-23 2014-06-17 Medtronic Minimed, Inc. Ranking and switching of wireless channels in a body area network of medical devices
US20110152970A1 (en) * 2009-12-23 2011-06-23 Medtronic Minimed, Inc. Location-based ranking and switching of wireless channels in a body area network of medical devices
EP2525848B1 (en) 2010-01-22 2016-08-03 DEKA Products Limited Partnership System for shape-memory alloy wire control
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
CA3096110C (en) 2010-03-24 2023-11-14 Abbott Diabetes Care Inc. Medical device inserters and processes of inserting and using medical devices
WO2011154941A2 (en) 2010-06-07 2011-12-15 Beta-O2 Technologies Ltd. Multiple-layer immune barrier for donor cells
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8603032B2 (en) 2010-10-15 2013-12-10 Medtronic Minimed, Inc. Medical device with membrane keypad sealing element, and related manufacturing method
US8603033B2 (en) 2010-10-15 2013-12-10 Medtronic Minimed, Inc. Medical device and related assembly having an offset element for a piezoelectric speaker
US8562565B2 (en) 2010-10-15 2013-10-22 Medtronic Minimed, Inc. Battery shock absorber for a portable medical device
US8479595B2 (en) 2010-10-20 2013-07-09 Medtronic Minimed, Inc. Sensor assembly and medical device incorporating same
US8474332B2 (en) 2010-10-20 2013-07-02 Medtronic Minimed, Inc. Sensor assembly and medical device incorporating same
US8495918B2 (en) 2010-10-20 2013-07-30 Medtronic Minimed, Inc. Sensor assembly and medical device incorporating same
US8197444B1 (en) 2010-12-22 2012-06-12 Medtronic Minimed, Inc. Monitoring the seating status of a fluid reservoir in a fluid infusion device
US8469942B2 (en) 2010-12-22 2013-06-25 Medtronic Minimed, Inc. Occlusion detection for a fluid infusion device
US8690855B2 (en) 2010-12-22 2014-04-08 Medtronic Minimed, Inc. Fluid reservoir seating procedure for a fluid infusion device
US8628510B2 (en) 2010-12-22 2014-01-14 Medtronic Minimed, Inc. Monitoring the operating health of a force sensor in a fluid infusion device
US9808616B2 (en) 2011-01-14 2017-11-07 The Regents Of The University Of Michigan Regenerative peripheral nerve interface
US8870829B2 (en) 2011-02-22 2014-10-28 Medtronic Minimed, Inc. Fluid infusion device and related sealing assembly for a needleless fluid reservoir
US9463309B2 (en) 2011-02-22 2016-10-11 Medtronic Minimed, Inc. Sealing assembly and structure for a fluid infusion device having a needled fluid reservoir
US9283318B2 (en) 2011-02-22 2016-03-15 Medtronic Minimed, Inc. Flanged sealing element and needle guide pin assembly for a fluid infusion device having a needled fluid reservoir
US9393399B2 (en) 2011-02-22 2016-07-19 Medtronic Minimed, Inc. Sealing assembly for a fluid reservoir of a fluid infusion device
US8614596B2 (en) 2011-02-28 2013-12-24 Medtronic Minimed, Inc. Systems and methods for initializing a voltage bus and medical devices incorporating same
US9101305B2 (en) 2011-03-09 2015-08-11 Medtronic Minimed, Inc. Glucose sensor product and related manufacturing and packaging methods
US8564447B2 (en) 2011-03-18 2013-10-22 Medtronic Minimed, Inc. Battery life indication techniques for an electronic device
US9018893B2 (en) 2011-03-18 2015-04-28 Medtronic Minimed, Inc. Power control techniques for an electronic device
WO2012176047A1 (en) 2011-06-20 2012-12-27 Palti Yoram Prof Continuous monitoring of glucose and other living body constituents
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
JP6443802B2 (en) 2011-11-07 2018-12-26 アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. Analyte monitoring apparatus and method
FI3831283T3 (en) 2011-12-11 2023-06-01 Abbott Diabetes Care Inc Analyte sensor devices, connections, and methods
US9610401B2 (en) 2012-01-13 2017-04-04 Medtronic Minimed, Inc. Infusion set component with modular fluid channel element
WO2013134519A2 (en) 2012-03-07 2013-09-12 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US8603026B2 (en) 2012-03-20 2013-12-10 Medtronic Minimed, Inc. Dynamic pulse-width modulation motor control and medical device incorporating same
US8603027B2 (en) 2012-03-20 2013-12-10 Medtronic Minimed, Inc. Occlusion detection using pulse-width modulation and medical device incorporating same
US8523803B1 (en) 2012-03-20 2013-09-03 Medtronic Minimed, Inc. Motor health monitoring and medical device incorporating same
US10391242B2 (en) 2012-06-07 2019-08-27 Medtronic Minimed, Inc. Diabetes therapy management system for recommending bolus calculator adjustments
US9333292B2 (en) 2012-06-26 2016-05-10 Medtronic Minimed, Inc. Mechanically actuated fluid infusion device
US8761717B1 (en) 2012-08-07 2014-06-24 Brian K. Buchheit Safety feature to disable an electronic device when a wireless implantable medical device (IMD) is proximate
US8808269B2 (en) 2012-08-21 2014-08-19 Medtronic Minimed, Inc. Reservoir plunger position monitoring and medical device incorporating same
US20140066884A1 (en) 2012-08-30 2014-03-06 Medtronic Minimed, Inc. Sensor model supervisor for a closed-loop insulin infusion system
US9623179B2 (en) 2012-08-30 2017-04-18 Medtronic Minimed, Inc. Safeguarding techniques for a closed-loop insulin infusion system
US9662445B2 (en) 2012-08-30 2017-05-30 Medtronic Minimed, Inc. Regulating entry into a closed-loop operating mode of an insulin infusion system
US10496797B2 (en) 2012-08-30 2019-12-03 Medtronic Minimed, Inc. Blood glucose validation for a closed-loop operating mode of an insulin infusion system
US9849239B2 (en) 2012-08-30 2017-12-26 Medtronic Minimed, Inc. Generation and application of an insulin limit for a closed-loop operating mode of an insulin infusion system
US10130767B2 (en) 2012-08-30 2018-11-20 Medtronic Minimed, Inc. Sensor model supervisor for a closed-loop insulin infusion system
US9878096B2 (en) 2012-08-30 2018-01-30 Medtronic Minimed, Inc. Generation of target glucose values for a closed-loop operating mode of an insulin infusion system
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
WO2014041190A1 (en) * 2012-09-17 2014-03-20 Brains Online Holding B.V. Rod shaped implantable biosensor
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US8870818B2 (en) 2012-11-15 2014-10-28 Medtronic Minimed, Inc. Systems and methods for alignment and detection of a consumable component
US9522223B2 (en) 2013-01-18 2016-12-20 Medtronic Minimed, Inc. Systems for fluid reservoir retention
US9033924B2 (en) 2013-01-18 2015-05-19 Medtronic Minimed, Inc. Systems for fluid reservoir retention
US9107994B2 (en) 2013-01-18 2015-08-18 Medtronic Minimed, Inc. Systems for fluid reservoir retention
US9308321B2 (en) 2013-02-18 2016-04-12 Medtronic Minimed, Inc. Infusion device having gear assembly initialization
US8920381B2 (en) 2013-04-12 2014-12-30 Medtronic Minimed, Inc. Infusion set with improved bore configuration
WO2015003145A1 (en) 2013-07-03 2015-01-08 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US9433731B2 (en) 2013-07-19 2016-09-06 Medtronic Minimed, Inc. Detecting unintentional motor motion and infusion device incorporating same
AU2014290745A1 (en) 2013-07-19 2015-12-17 Dexcom, Inc. Time averaged basal rate optimizer
US9402949B2 (en) 2013-08-13 2016-08-02 Medtronic Minimed, Inc. Detecting conditions associated with medical device operations using matched filters
US9880528B2 (en) 2013-08-21 2018-01-30 Medtronic Minimed, Inc. Medical devices and related updating methods and systems
US9889257B2 (en) 2013-08-21 2018-02-13 Medtronic Minimed, Inc. Systems and methods for updating medical devices
US9259528B2 (en) 2013-08-22 2016-02-16 Medtronic Minimed, Inc. Fluid infusion device with safety coupling
US9750878B2 (en) 2013-12-11 2017-09-05 Medtronic Minimed, Inc. Closed-loop control of glucose according to a predicted blood glucose trajectory
US9750877B2 (en) 2013-12-11 2017-09-05 Medtronic Minimed, Inc. Predicted time to assess and/or control a glycemic state
US9849240B2 (en) 2013-12-12 2017-12-26 Medtronic Minimed, Inc. Data modification for predictive operations and devices incorporating same
US10105488B2 (en) 2013-12-12 2018-10-23 Medtronic Minimed, Inc. Predictive infusion device operations and related methods and systems
US9694132B2 (en) 2013-12-19 2017-07-04 Medtronic Minimed, Inc. Insertion device for insertion set
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9399096B2 (en) 2014-02-06 2016-07-26 Medtronic Minimed, Inc. Automatic closed-loop control adjustments and infusion systems incorporating same
US9861748B2 (en) 2014-02-06 2018-01-09 Medtronic Minimed, Inc. User-configurable closed-loop notifications and infusion systems incorporating same
US9486623B2 (en) 2014-03-05 2016-11-08 Rainbow Medical Ltd. Electrical stimulation of a pancreas
US9610402B2 (en) 2014-03-24 2017-04-04 Medtronic Minimed, Inc. Transcutaneous conduit insertion mechanism with a living hinge for use with a fluid infusion patch pump device
US10001450B2 (en) 2014-04-18 2018-06-19 Medtronic Minimed, Inc. Nonlinear mapping technique for a physiological characteristic sensor
US10232113B2 (en) 2014-04-24 2019-03-19 Medtronic Minimed, Inc. Infusion devices and related methods and systems for regulating insulin on board
US9681828B2 (en) 2014-05-01 2017-06-20 Medtronic Minimed, Inc. Physiological characteristic sensors and methods for forming such sensors
US10275572B2 (en) 2014-05-01 2019-04-30 Medtronic Minimed, Inc. Detecting blockage of a reservoir cavity during a seating operation of a fluid infusion device
US10007765B2 (en) 2014-05-19 2018-06-26 Medtronic Minimed, Inc. Adaptive signal processing for infusion devices and related methods and systems
US10152049B2 (en) 2014-05-19 2018-12-11 Medtronic Minimed, Inc. Glucose sensor health monitoring and related methods and systems
US10274349B2 (en) 2014-05-19 2019-04-30 Medtronic Minimed, Inc. Calibration factor adjustments for infusion devices and related methods and systems
US9839753B2 (en) 2014-09-26 2017-12-12 Medtronic Minimed, Inc. Systems for managing reservoir chamber pressure
US9833563B2 (en) 2014-09-26 2017-12-05 Medtronic Minimed, Inc. Systems for managing reservoir chamber pressure
US10279126B2 (en) 2014-10-07 2019-05-07 Medtronic Minimed, Inc. Fluid conduit assembly with gas trapping filter in the fluid flow path
CN106999118B (en) 2014-10-13 2020-07-17 葡萄糖传感器公司 Analyte sensing device
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
EP3933845A3 (en) 2014-10-27 2022-06-22 Aseko, Inc. Subcutaneous outpatient management
US10314725B2 (en) 2014-11-13 2019-06-11 The Regents Of The University Of Michigan Method for amplifying signals from individual nerve fascicles
US9833564B2 (en) 2014-11-25 2017-12-05 Medtronic Minimed, Inc. Fluid conduit assembly with air venting features
US10195341B2 (en) 2014-11-26 2019-02-05 Medtronic Minimed, Inc. Systems and methods for fluid infusion device with automatic reservoir fill
US9987420B2 (en) 2014-11-26 2018-06-05 Medtronic Minimed, Inc. Systems and methods for fluid infusion device with automatic reservoir fill
US9636453B2 (en) 2014-12-04 2017-05-02 Medtronic Minimed, Inc. Advance diagnosis of infusion device operating mode viability
US9943645B2 (en) 2014-12-04 2018-04-17 Medtronic Minimed, Inc. Methods for operating mode transitions and related infusion devices and systems
US9937292B2 (en) 2014-12-09 2018-04-10 Medtronic Minimed, Inc. Systems for filling a fluid infusion device reservoir
US10307535B2 (en) 2014-12-19 2019-06-04 Medtronic Minimed, Inc. Infusion devices and related methods and systems for preemptive alerting
US10265031B2 (en) 2014-12-19 2019-04-23 Medtronic Minimed, Inc. Infusion devices and related methods and systems for automatic alert clearing
US10307528B2 (en) 2015-03-09 2019-06-04 Medtronic Minimed, Inc. Extensible infusion devices and related methods
US10449298B2 (en) 2015-03-26 2019-10-22 Medtronic Minimed, Inc. Fluid injection devices and related methods
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
AU2016260547B2 (en) 2015-05-14 2020-09-03 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US9999721B2 (en) 2015-05-26 2018-06-19 Medtronic Minimed, Inc. Error handling in infusion devices with distributed motor control and related operating methods
US10137243B2 (en) 2015-05-26 2018-11-27 Medtronic Minimed, Inc. Infusion devices with distributed motor control and related operating methods
US10575767B2 (en) 2015-05-29 2020-03-03 Medtronic Minimed, Inc. Method for monitoring an analyte, analyte sensor and analyte monitoring apparatus
US9879668B2 (en) 2015-06-22 2018-01-30 Medtronic Minimed, Inc. Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and an optical sensor
US9878095B2 (en) 2015-06-22 2018-01-30 Medtronic Minimed, Inc. Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and multiple sensor contact elements
US9993594B2 (en) 2015-06-22 2018-06-12 Medtronic Minimed, Inc. Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and rotor position sensors
US10010668B2 (en) 2015-06-22 2018-07-03 Medtronic Minimed, Inc. Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and a force sensor
US9987425B2 (en) 2015-06-22 2018-06-05 Medtronic Minimed, Inc. Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and sensor contact elements
WO2017031440A1 (en) 2015-08-20 2017-02-23 Aseko, Inc. Diabetes management therapy advisor
US20170053552A1 (en) 2015-08-21 2017-02-23 Medtronic Minimed, Inc. Management and prioritization of the delivery of glycemic insight messages
US10543314B2 (en) 2015-08-21 2020-01-28 Medtronic Minimed, Inc. Personalized parameter modeling with signal calibration based on historical data
US10293108B2 (en) 2015-08-21 2019-05-21 Medtronic Minimed, Inc. Infusion devices and related patient ratio adjustment methods
US10463297B2 (en) 2015-08-21 2019-11-05 Medtronic Minimed, Inc. Personalized event detection methods and related devices and systems
US10201657B2 (en) 2015-08-21 2019-02-12 Medtronic Minimed, Inc. Methods for providing sensor site rotation feedback and related infusion devices and systems
US10117992B2 (en) 2015-09-29 2018-11-06 Medtronic Minimed, Inc. Infusion devices and related rescue detection methods
US11501867B2 (en) 2015-10-19 2022-11-15 Medtronic Minimed, Inc. Medical devices and related event pattern presentation methods
US11666702B2 (en) 2015-10-19 2023-06-06 Medtronic Minimed, Inc. Medical devices and related event pattern treatment recommendation methods
US10146911B2 (en) 2015-10-23 2018-12-04 Medtronic Minimed, Inc. Medical devices and related methods and systems for data transfer
US10037722B2 (en) 2015-11-03 2018-07-31 Medtronic Minimed, Inc. Detecting breakage in a display element
US10449306B2 (en) 2015-11-25 2019-10-22 Medtronics Minimed, Inc. Systems for fluid delivery with wicking membrane
EP3445872A1 (en) 2016-04-20 2019-02-27 Glusense Ltd. Fret-based glucose-detection molecules
US10589038B2 (en) 2016-04-27 2020-03-17 Medtronic Minimed, Inc. Set connector systems for venting a fluid reservoir
CA3042866A1 (en) 2016-11-03 2018-05-11 Klearchos K. Papas Encapsulation device systems with oxygen sensors with or without exogenous oxygen delivery
SG10202104562TA (en) 2016-11-03 2021-06-29 Univ Arizona Stacked tissue encapsulation device systems with or without oxygen delivery
KR102649881B1 (en) 2016-11-03 2024-03-20 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 Methods and systems for real-time assessment of cells in encapsulation devices pre-and post-transplantation
KR102607115B1 (en) * 2016-11-03 2023-11-30 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 Methods, systems, and implantable devices for enhancing blood glucose regulation
US11097051B2 (en) 2016-11-04 2021-08-24 Medtronic Minimed, Inc. Methods and apparatus for detecting and reacting to insufficient hypoglycemia response
US10238030B2 (en) 2016-12-06 2019-03-26 Medtronic Minimed, Inc. Wireless medical device with a complementary split ring resonator arrangement for suppression of electromagnetic interference
US10272201B2 (en) 2016-12-22 2019-04-30 Medtronic Minimed, Inc. Insertion site monitoring methods and related infusion devices and systems
US11071478B2 (en) 2017-01-23 2021-07-27 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
US10500135B2 (en) 2017-01-30 2019-12-10 Medtronic Minimed, Inc. Fluid reservoir and systems for filling a fluid reservoir of a fluid infusion device
US10532165B2 (en) 2017-01-30 2020-01-14 Medtronic Minimed, Inc. Fluid reservoir and systems for filling a fluid reservoir of a fluid infusion device
US10363365B2 (en) 2017-02-07 2019-07-30 Medtronic Minimed, Inc. Infusion devices and related consumable calibration methods
US10552580B2 (en) 2017-02-07 2020-02-04 Medtronic Minimed, Inc. Infusion system consumables and related calibration methods
US10646649B2 (en) 2017-02-21 2020-05-12 Medtronic Minimed, Inc. Infusion devices and fluid identification apparatuses and methods
US11207463B2 (en) 2017-02-21 2021-12-28 Medtronic Minimed, Inc. Apparatuses, systems, and methods for identifying an infusate in a reservoir of an infusion device
US20190120785A1 (en) 2017-10-24 2019-04-25 Dexcom, Inc. Pre-connected analyte sensors
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
EP3784312A1 (en) 2018-04-24 2021-03-03 DEKA Products Limited Partnership Apparatus and system for fluid delivery
US20190350443A1 (en) * 2018-05-21 2019-11-21 Mark D. Noar Method For Monitoring A Property Of Tissue Of An Internal Bodily Organ And Adjusting The Tissue Property
CN109157229B (en) * 2018-06-29 2024-03-29 南京医科大学 Continuous arterial blood glucose monitoring equipment and control method thereof
US20220134074A1 (en) * 2020-10-30 2022-05-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for encapsulation devices for housing cells and agents

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140963A (en) * 1972-01-03 1979-02-20 Siemens Aktiengesellschaft Device for measuring sugar concentration
US3837339A (en) * 1972-02-03 1974-09-24 Whittaker Corp Blood glucose level monitoring-alarm system and method therefor
US4136101A (en) * 1978-02-03 1979-01-23 American Cyanamid Company Process for preparing dialkyl (p-aminobenzoyl) glutamates
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4332893A (en) * 1980-06-13 1982-06-01 Rosenberg Ralph A Process for the production of an insulin-producing cell line of pancreatic beta cells
US4374987A (en) * 1980-08-14 1983-02-22 American Cyanamid Company Process for the preparation of high purity methotrexate and derivatives thereof
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4436094A (en) * 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
US4375987A (en) * 1981-11-23 1983-03-08 W. R. Grace & Co. Additive combination for hydraulic cement compositions
US4677982A (en) * 1981-12-31 1987-07-07 New York University Infrared transcutaneous communicator and method of using same
US4798786A (en) * 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
IT1170375B (en) * 1983-04-19 1987-06-03 Giuseppe Bombardieri Implantable device for measuring body fluid parameters
US4689293A (en) * 1983-06-06 1987-08-25 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4803168A (en) * 1983-09-01 1989-02-07 Damon Biotech, Inc. Microencapsulation with polymers
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
JPH0739211B2 (en) * 1985-08-06 1995-05-01 三井東圧化学株式会社 Method of manufacturing optical recording medium
US4704029A (en) * 1985-12-26 1987-11-03 Research Corporation Blood glucose monitor
JPS62213760A (en) * 1986-03-14 1987-09-19 日本電気株式会社 Artificial pancreas
DE3713060A1 (en) * 1986-05-02 1987-11-05 Siemens Ag Measuring device for a physiological component dissolved in liquid
US4703756A (en) * 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
DE3700119A1 (en) * 1987-01-03 1988-07-14 Inst Diabetestechnologie Gemei IMPLANTABLE ELECTROCHEMICAL SENSOR
US4822336A (en) * 1988-03-04 1989-04-18 Ditraglia John Blood glucose level sensing
US5101814A (en) * 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose

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