CA2039815A1 - Hydroxyapatite coatings of substrates - Google Patents

Hydroxyapatite coatings of substrates

Info

Publication number
CA2039815A1
CA2039815A1 CA002039815A CA2039815A CA2039815A1 CA 2039815 A1 CA2039815 A1 CA 2039815A1 CA 002039815 A CA002039815 A CA 002039815A CA 2039815 A CA2039815 A CA 2039815A CA 2039815 A1 CA2039815 A1 CA 2039815A1
Authority
CA
Canada
Prior art keywords
coating
substrates
trough
substrate
hydroxyapatite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002039815A
Other languages
French (fr)
Other versions
CA2039815C (en
Inventor
Brent R. Constantz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norian Corp
Original Assignee
Brent R. Constantz
Norian Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brent R. Constantz, Norian Corporation filed Critical Brent R. Constantz
Publication of CA2039815A1 publication Critical patent/CA2039815A1/en
Application granted granted Critical
Publication of CA2039815C publication Critical patent/CA2039815C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901—Method of manufacturing prosthetic device

Abstract

Methods, compositions and apparatus are provided for coating a substrate with a strongly adherent hydroxyapatite coating, which allows for ingrowth of natural bane and strong bonding between the coating and the substrate. The procedure provides for coating under conditions which form sticky particles which bind to the substrate to from a crystalline hydroxyapatite coating.
The coating has particular application for prostheses, where porous areas of the prostheses are completely coated with a thin sturdy coating of hydroxyapatite.
The apparatus comprises a coating trough in which the substrates are present and the reactive components added. The medium is recirculated in an outer circuit through a distribution tank solution preparation tank and coating trough. Means are provided for maintaining temperature and pH. The substrates are maintained in a line normal to the flow in the trough and can be rotated to ensure even coating.
CA002039815A 1990-04-05 1991-04-04 Hydroxyapatite coatings of substrates Expired - Lifetime CA2039815C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/504,941 US5164187A (en) 1990-04-05 1990-04-05 Hydroxyapatite prosthesis coatings
US07/504,941 1990-04-05

Publications (2)

Publication Number Publication Date
CA2039815A1 true CA2039815A1 (en) 1991-10-06
CA2039815C CA2039815C (en) 2003-06-17

Family

ID=24008349

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002039815A Expired - Lifetime CA2039815C (en) 1990-04-05 1991-04-04 Hydroxyapatite coatings of substrates

Country Status (10)

Country Link
US (2) US5164187A (en)
EP (1) EP0450939B1 (en)
JP (1) JP3340447B2 (en)
AT (1) ATE147640T1 (en)
CA (1) CA2039815C (en)
DE (1) DE69124129T2 (en)
DK (1) DK0450939T3 (en)
ES (1) ES2097791T3 (en)
GR (1) GR3022845T3 (en)
IE (1) IE911123A1 (en)

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Also Published As

Publication number Publication date
ES2097791T3 (en) 1997-04-16
GR3022845T3 (en) 1997-06-30
US5164187A (en) 1992-11-17
IE911123A1 (en) 1991-10-09
JP3340447B2 (en) 2002-11-05
ATE147640T1 (en) 1997-02-15
JPH04224747A (en) 1992-08-14
DK0450939T3 (en) 1997-07-14
EP0450939A3 (en) 1992-12-16
EP0450939A2 (en) 1991-10-09
US5279831A (en) 1994-01-18
DE69124129D1 (en) 1997-02-27
CA2039815C (en) 2003-06-17
EP0450939B1 (en) 1997-01-15
DE69124129T2 (en) 1997-07-10

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