CA2007884A1 - Hydrophilic lubricious coatings - Google Patents

Hydrophilic lubricious coatings

Info

Publication number
CA2007884A1
CA2007884A1 CA2007884A CA2007884A CA2007884A1 CA 2007884 A1 CA2007884 A1 CA 2007884A1 CA 2007884 A CA2007884 A CA 2007884A CA 2007884 A CA2007884 A CA 2007884A CA 2007884 A1 CA2007884 A1 CA 2007884A1
Authority
CA
Canada
Prior art keywords
coatings
contacted
hydrophilic lubricious
solution
lubricious coatings
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2007884A
Other languages
French (fr)
Other versions
CA2007884C (en
Inventor
You-Ling Fan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Union Carbide Chemicals and Plastics Technology LLC
Original Assignee
You-Ling Fan
Union Carbide Corporation
Union Carbide Chemicals And Plastics Company Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by You-Ling Fan, Union Carbide Corporation, Union Carbide Chemicals And Plastics Company Inc. filed Critical You-Ling Fan
Publication of CA2007884A1 publication Critical patent/CA2007884A1/en
Application granted granted Critical
Publication of CA2007884C publication Critical patent/CA2007884C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D5/00Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
    • B05D5/04Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a surface receptive to ink or other liquid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D3/00Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
    • B05D3/10Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by other chemical means
    • B05D3/101Pretreatment of polymeric substrate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/62Polymers of compounds having carbon-to-carbon double bonds
    • C08G18/6216Polymers of alpha-beta ethylenically unsaturated carboxylic acids or of derivatives thereof
    • C08G18/625Polymers of alpha-beta ethylenically unsaturated carboxylic acids; hydrolyzed polymers of esters of these acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/703Isocyanates or isothiocyanates transformed in a latent form by physical means
    • C08G18/705Dispersions of isocyanates or isothiocyanates in a liquid medium
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/042Coating with two or more layers, where at least one layer of a composition contains a polymer binder
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/0427Coating with only one layer of a composition containing a polymer binder
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/043Improving the adhesiveness of the coatings per se, e.g. forming primers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/046Forming abrasion-resistant coatings; Forming surface-hardening coatings
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/056Forming hydrophilic coatings
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/06Coating with compositions not containing macromolecular substances
    • C08J7/065Low-molecular-weight organic substances, e.g. absorption of additives in the surface of the article
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D2201/00Polymeric substrate or laminate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D3/00Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
    • B05D3/10Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by other chemical means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D5/00Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
    • B05D5/08Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2375/00Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
    • C08J2375/04Polyurethanes
    • C08J2375/12Polyurethanes from compounds containing nitrogen and active hydrogen, the nitrogen atom not being part of an isocyanate group
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2433/00Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2433/04Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters
    • C08J2433/06Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C08J2433/08Homopolymers or copolymers of acrylic acid esters

Abstract

A new method is provided to impart a hydrophilic lubricious coating onto articles such as medical devices. A device, for example a catheter, is first contacted with a polyisocyanate solution, to provide coupling, then contacted with a poly(carboxylic acid) solution to give a coating, and is then finally oven dried. These coatings have lubricity that only becomes manifest upon exposure to water or body fluids, and moreover, are also long lasting and have good abrasion resistance. This combination of properties is not available from other currently used or proposed coatings such as Teflon.
CA002007884A 1989-01-17 1990-01-16 Hydrophilic lubricious coatings Expired - Lifetime CA2007884C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US449,777 1982-12-14
US29733189A 1989-01-17 1989-01-17
US297,331 1989-01-17
US07/449,777 US5091205A (en) 1989-01-17 1989-12-22 Hydrophilic lubricious coatings

Publications (2)

Publication Number Publication Date
CA2007884A1 true CA2007884A1 (en) 1990-07-17
CA2007884C CA2007884C (en) 1994-07-12

Family

ID=26970100

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002007884A Expired - Lifetime CA2007884C (en) 1989-01-17 1990-01-16 Hydrophilic lubricious coatings

Country Status (8)

Country Link
US (1) US5091205A (en)
EP (1) EP0379156B1 (en)
JP (1) JPH0790040B2 (en)
AT (1) ATE136565T1 (en)
CA (1) CA2007884C (en)
DE (1) DE69026396T2 (en)
ES (1) ES2085290T3 (en)
GR (1) GR3019636T3 (en)

Families Citing this family (419)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02299663A (en) * 1989-05-15 1990-12-11 Unitika Ltd Anti-infectious catheter
DE69002295T2 (en) 1989-09-25 1993-11-04 Schneider Usa Inc MULTILAYER EXTRUSION AS A METHOD FOR PRODUCING BALLOONS FOR VESSEL PLASTICS.
US5843089A (en) 1990-12-28 1998-12-01 Boston Scientific Corporation Stent lining
US5304121A (en) * 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5135516A (en) * 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US5674192A (en) * 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
JPH0783761B2 (en) * 1990-10-04 1995-09-13 テルモ株式会社 Medical equipment
US5295978A (en) * 1990-12-28 1994-03-22 Union Carbide Chemicals & Plastics Technology Corporation Biocompatible hydrophilic complexes and process for preparation and use
US6524274B1 (en) 1990-12-28 2003-02-25 Scimed Life Systems, Inc. Triggered release hydrogel drug delivery system
GB9109122D0 (en) * 1991-04-25 1991-06-12 Beam Tech Ltd Treatment of polyurethane surfaces
GB9109068D0 (en) * 1991-04-25 1991-06-12 Beam Tech Ltd Tubular device with hydrophilic surface
GB9109069D0 (en) * 1991-04-25 1991-06-12 Pharma Plast Int As Catheter
US5195969A (en) 1991-04-26 1993-03-23 Boston Scientific Corporation Co-extruded medical balloons and catheter using such balloons
US5284157A (en) * 1991-07-26 1994-02-08 Ortho Pharmaceutical Corporation Elastomeric film products with improved chemical resistance
JPH0522071U (en) * 1991-09-10 1993-03-23 オカモト株式会社 Rubber mold
JP2744155B2 (en) * 1991-10-28 1998-04-28 株式会社クリニカル・サプライ Antithrombotic medical device having lubricity when wet and method for producing the same
US5254089A (en) * 1992-04-02 1993-10-19 Boston Scientific Corp. Medication dispensing balloon catheter
US5395331A (en) * 1992-04-27 1995-03-07 Minnesota Mining And Manufacturing Company Retrograde coronary sinus catheter having a ribbed balloon
DE4222380A1 (en) * 1992-07-08 1994-01-13 Ernst Peter Prof Dr M Strecker Endoprosthesis implantable percutaneously in a patient's body
US5503631A (en) * 1992-10-09 1996-04-02 Terumo Kabushiki Kaisha Lubricious catheter balloon for vasodilation
US5487730A (en) * 1992-12-30 1996-01-30 Medtronic, Inc. Balloon catheter with balloon surface retention means
CA2114697C (en) * 1993-02-08 2006-06-13 Kenichi Shimura Medical tool having lubricious surface in a wetted state and method for production thereof
EP0746362B1 (en) * 1993-08-23 2002-01-16 Boston Scientific Corporation Improved balloon catheter
US6896842B1 (en) * 1993-10-01 2005-05-24 Boston Scientific Corporation Medical device balloons containing thermoplastic elastomers
WO1995009667A1 (en) 1993-10-01 1995-04-13 Boston Scientific Corporation Medical device balloons containing thermoplastic elastomers
US5409012A (en) * 1993-12-30 1995-04-25 Boston Scientific Corporation Sample collection using catheter with expandable member
US5599298A (en) * 1993-12-30 1997-02-04 Boston Scientific Corporation Bodily sample collection balloon catheter method
US5588962A (en) * 1994-03-29 1996-12-31 Boston Scientific Corporation Drug treatment of diseased sites deep within the body
US5670558A (en) * 1994-07-07 1997-09-23 Terumo Kabushiki Kaisha Medical instruments that exhibit surface lubricity when wetted
US5454373A (en) * 1994-07-20 1995-10-03 Boston Scientific Corporation Medical acoustic imaging
US5558900A (en) * 1994-09-22 1996-09-24 Fan; You-Ling One-step thromboresistant, lubricious coating
US5652225A (en) * 1994-10-04 1997-07-29 St. Elizabeth's Medical Center Of Boston, Inc. Methods and products for nucleic acid delivery
US5702754A (en) * 1995-02-22 1997-12-30 Meadox Medicals, Inc. Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with such coatings
US6468649B1 (en) 1995-02-22 2002-10-22 Scimed Life Systems, Inc. Antimicrobial adhesion surface
US6558798B2 (en) 1995-02-22 2003-05-06 Scimed Life Systems, Inc. Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity
US6231600B1 (en) 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US20070073384A1 (en) * 1995-03-01 2007-03-29 Boston Scientific Scimed, Inc. Longitudinally flexible expandable stent
US7204848B1 (en) 1995-03-01 2007-04-17 Boston Scientific Scimed, Inc. Longitudinally flexible expandable stent
US5601538A (en) * 1995-03-07 1997-02-11 Medtronic, Inc. Flow directed catheter with hydrophilic distal end
US6306144B1 (en) * 1996-11-01 2001-10-23 Scimed Life Systems, Inc. Selective coating of a balloon catheter with lubricious material for stent deployment
JPH11504829A (en) * 1995-05-05 1999-05-11 アドバンスト・カーディオバスキュラー・システムズ・インコーポレイテッド In-pipe device with anti-friction surface
GB9511233D0 (en) * 1995-06-03 1995-07-26 Watson Jermey Lubricious coatings
US5620738A (en) * 1995-06-07 1997-04-15 Union Carbide Chemicals & Plastics Technology Corporation Non-reactive lubicious coating process
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US5731087A (en) * 1995-06-07 1998-03-24 Union Carbide Chemicals & Plastics Technology Corporation Lubricious coatings containing polymers with vinyl and carboxylic acid moieties
MXPA96003950A (en) * 1995-09-08 2009-03-25 Union Carbide Chem Plastic Biostatic coatings and processes.
CN1052915C (en) * 1995-11-27 2000-05-31 中国医学科学院生物医学工程研究所 Medical carrier of protein coat for carrying gene and its prodn. method
SE9600276D0 (en) 1996-01-25 1996-01-25 Astra Ab A wetting device for wetting a hydrophilic catheter and a urine collection bag incorporating said device
US5868719A (en) * 1997-01-15 1999-02-09 Boston Scientific Corporation Drug delivery balloon catheter device
US6494861B1 (en) 1997-01-15 2002-12-17 Boston Scientific Corporation Drug delivery system
US5997517A (en) * 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
EP0879607A3 (en) * 1997-05-23 1999-05-19 Hüls Aktiengesellschaft Method and reducing friction of hydrophilic surfaces
US6221467B1 (en) 1997-06-03 2001-04-24 Scimed Life Systems, Inc. Coating gradient for lubricious coatings on balloon catheters
US5902631A (en) * 1997-06-03 1999-05-11 Wang; Lixiao Lubricity gradient for medical devices
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
EP0991702B2 (en) 1997-06-20 2017-07-19 Coloplast A/S A hydrophilic coating
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US5900270A (en) * 1997-09-22 1999-05-04 Cobe Laboratories, Inc. Technique for testing and coating a microporous membrane
WO1999019004A2 (en) * 1997-10-15 1999-04-22 Tyco Group S.A.R.L. Lubricious coating
US6221425B1 (en) 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
AU3212199A (en) * 1998-03-31 1999-10-18 Scimed Life Systems, Inc. Temperature controlled solute delivery system
US7713297B2 (en) * 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US6086970A (en) * 1998-04-28 2000-07-11 Scimed Life Systems, Inc. Lubricious surface extruded tubular members for medical devices
US8177743B2 (en) 1998-05-18 2012-05-15 Boston Scientific Scimed, Inc. Localized delivery of drug agents
US6280411B1 (en) * 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
US6206283B1 (en) * 1998-12-23 2001-03-27 At&T Corp. Method and apparatus for transferring money via a telephone call
US6087415A (en) * 1998-06-11 2000-07-11 Johnson & Johnson Vision Care, Inc. Biomedical devices with hydrophilic coatings
US6500481B1 (en) 1998-06-11 2002-12-31 Johnson & Johnson Vision Care, Inc. Biomedical devices with amid-containing coatings
US6369039B1 (en) 1998-06-30 2002-04-09 Scimed Life Sytems, Inc. High efficiency local drug delivery
US6248127B1 (en) 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
US6335029B1 (en) 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
US7141246B2 (en) * 1998-10-07 2006-11-28 Sherwood Services Ag Lubricious coating
US7820734B2 (en) * 1998-10-07 2010-10-26 Tyco Healthcare Group Lp Antimicrobial lubricious coating
US6645483B2 (en) * 1998-10-07 2003-11-11 Sherwood Services Ag Lubricious coating
DE69905487T3 (en) 1998-11-20 2007-06-06 Coloplast A/S METHOD FOR STERILIZING MEDICAL DEVICES WITH HYDROPHILIC COATING
US6986868B2 (en) 1998-11-20 2006-01-17 Coloplast A/S Method for sterilizing a medical device having a hydrophilic coating
EP1148898A1 (en) * 1999-01-28 2001-10-31 Union Carbide Chemicals & Plastics Technology Corporation Lubricious medical devices
US8506519B2 (en) 1999-02-16 2013-08-13 Flowcardia, Inc. Pre-shaped therapeutic catheter
US6855123B2 (en) * 2002-08-02 2005-02-15 Flow Cardia, Inc. Therapeutic ultrasound system
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6607598B2 (en) 1999-04-19 2003-08-19 Scimed Life Systems, Inc. Device for protecting medical devices during a coating process
US6673053B2 (en) * 1999-05-07 2004-01-06 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising an antiblock agent
US6176849B1 (en) 1999-05-21 2001-01-23 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hydrophobic top coat
US6610035B2 (en) 1999-05-21 2003-08-26 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hybrid top coat
US6258121B1 (en) 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6458867B1 (en) 1999-09-28 2002-10-01 Scimed Life Systems, Inc. Hydrophilic lubricant coatings for medical devices
EP1233724A4 (en) * 1999-11-18 2004-03-10 Sts Biopolymers Inc Flexible sealed coil-like devices
CA2409093C (en) 2000-05-16 2009-07-21 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
US6506408B1 (en) 2000-07-13 2003-01-14 Scimed Life Systems, Inc. Implantable or insertable therapeutic agent delivery device
GB0020491D0 (en) 2000-08-18 2000-10-11 Angiomed Ag Stent with attached element and method of making such a stent
BRPI0113758B8 (en) * 2000-09-11 2021-06-22 Union Carbide Chemicals & Plastics Tech Corporation process for manufacturing a lubricated medical device capable of being detected by magnetic resonance imaging and medical device
US20020116049A1 (en) * 2000-09-22 2002-08-22 Scimed Life Systems, Inc. Stent
US8070792B2 (en) 2000-09-22 2011-12-06 Boston Scientific Scimed, Inc. Stent
US7803149B2 (en) * 2002-07-12 2010-09-28 Cook Incorporated Coated medical device
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
US7247338B2 (en) * 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
US8061006B2 (en) * 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US6945994B2 (en) 2001-12-05 2005-09-20 Boston Scientific Scimed, Inc. Combined balloon-expanding and self-expanding stent
US7537607B2 (en) * 2001-12-21 2009-05-26 Boston Scientific Scimed, Inc. Stent geometry for improved flexibility
US20040210289A1 (en) * 2002-03-04 2004-10-21 Xingwu Wang Novel nanomagnetic particles
US6981985B2 (en) * 2002-01-22 2006-01-03 Boston Scientific Scimed, Inc. Stent bumper struts
US20030139795A1 (en) 2002-01-23 2003-07-24 Scimed Life Systems, Inc. Stent delivery system loading tool
US7354450B2 (en) * 2002-01-30 2008-04-08 Boston Scientific Scimed, Inc. Stent with wishbone connectors and serpentine bands
US6887270B2 (en) 2002-02-08 2005-05-03 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US7993390B2 (en) * 2002-02-08 2011-08-09 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
US8133501B2 (en) 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US6756449B2 (en) * 2002-02-27 2004-06-29 Medtronic, Inc. AnB block copolymers containing poly (vinyl pyrrolidone) units, medical devices, and methods
US7951164B2 (en) * 2002-02-28 2011-05-31 Boston Scientific Scimed, Inc. Balloon folding apparatus, methods and products
US7758605B2 (en) * 2002-02-28 2010-07-20 Boston Scientific Scimed, Inc. Balloon folding apparatus, methods and products
US7144420B2 (en) * 2002-03-14 2006-12-05 Boston Scientific Scimed, Inc. Segmented spine
US8728510B1 (en) * 2002-03-15 2014-05-20 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing a bioadhesive material
US20030181972A1 (en) 2002-03-22 2003-09-25 Scimed Life Systems, Inc. MRI and x-ray compatible stent material
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US20030195609A1 (en) * 2002-04-10 2003-10-16 Scimed Life Systems, Inc. Hybrid stent
US6755824B2 (en) 2002-04-15 2004-06-29 Uab Research Foundation Platelet inhibitor eluting ablation catheter
US20030225448A1 (en) 2002-05-28 2003-12-04 Scimed Life Systems, Inc. Polar radiopaque marker for stent
US8211455B2 (en) 2002-06-19 2012-07-03 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US20040002752A1 (en) * 2002-06-26 2004-01-01 Scimed Life Systems, Inc. Sacrificial anode stent system
EP1516597A4 (en) * 2002-06-27 2010-11-10 Microport Medical Shanghai Co Drug eluting stent
DE60332949D1 (en) * 2002-07-24 2010-07-22 Covidien Ag METHOD FOR THE LUBRICATION OF INJECTION NEEDLES WITH RADIATION-CURABLE SILICONE MATERIAL
US8920826B2 (en) * 2002-07-31 2014-12-30 Boston Scientific Scimed, Inc. Medical imaging reference devices
US9955994B2 (en) 2002-08-02 2018-05-01 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US8133236B2 (en) * 2006-11-07 2012-03-13 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7449236B2 (en) * 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US6942677B2 (en) 2003-02-26 2005-09-13 Flowcardia, Inc. Ultrasound catheter apparatus
US7137963B2 (en) 2002-08-26 2006-11-21 Flowcardia, Inc. Ultrasound catheter for disrupting blood vessel obstructions
US7335180B2 (en) 2003-11-24 2008-02-26 Flowcardia, Inc. Steerable ultrasound catheter
US7220233B2 (en) 2003-04-08 2007-05-22 Flowcardia, Inc. Ultrasound catheter devices and methods
US7604608B2 (en) * 2003-01-14 2009-10-20 Flowcardia, Inc. Ultrasound catheter and methods for making and using same
US7083630B2 (en) 2002-08-29 2006-08-01 Scimed Life Systems, Inc. Devices and methods for fastening tissue layers
US20040044364A1 (en) * 2002-08-29 2004-03-04 Devries Robert Tissue fasteners and related deployment systems and methods
US9561123B2 (en) 2002-08-30 2017-02-07 C.R. Bard, Inc. Highly flexible stent and method of manufacture
US6878162B2 (en) * 2002-08-30 2005-04-12 Edwards Lifesciences Ag Helical stent having improved flexibility and expandability
US8012454B2 (en) * 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7588825B2 (en) * 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
US7883490B2 (en) * 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
JP2006505345A (en) * 2002-11-06 2006-02-16 エヴァレディ バッテリー カンパニー インク Shaving system
WO2004055167A2 (en) 2002-12-13 2004-07-01 Alphavax, Inc. Alphavirus particles and methods for preparation
US8105373B2 (en) 2002-12-16 2012-01-31 Boston Scientific Scimed, Inc. Flexible stent with improved axial strength
JP2006510756A (en) * 2002-12-20 2006-03-30 コロプラスト アクティーゼルスカブ Hydrophilic coatings and methods for preparing them
US6945957B2 (en) * 2002-12-30 2005-09-20 Scimed Life Systems, Inc. Valve treatment catheter and methods
US7179286B2 (en) 2003-02-21 2007-02-20 Boston Scientific Scimed, Inc. Stent with stepped connectors
EP1599248B1 (en) 2003-02-26 2010-06-02 Coloplast A/S A medical device having a coating comprising hydrogen peroxide and package therefor
US7318836B2 (en) 2003-03-11 2008-01-15 Boston Scientific Scimed, Inc. Covered stent
EP1462801A3 (en) * 2003-03-24 2005-01-05 Tepnel Lifecodes Methods for determining the negative control value for multi-analyte assays
US20040254419A1 (en) * 2003-04-08 2004-12-16 Xingwu Wang Therapeutic assembly
US20050149002A1 (en) * 2003-04-08 2005-07-07 Xingwu Wang Markers for visualizing interventional medical devices
US20050119725A1 (en) * 2003-04-08 2005-06-02 Xingwu Wang Energetically controlled delivery of biologically active material from an implanted medical device
US20060102871A1 (en) * 2003-04-08 2006-05-18 Xingwu Wang Novel composition
US20050149169A1 (en) * 2003-04-08 2005-07-07 Xingwu Wang Implantable medical device
US7279002B2 (en) * 2003-04-25 2007-10-09 Boston Scientific Scimed, Inc. Cutting stent and balloon
US20040220534A1 (en) * 2003-04-29 2004-11-04 Martens Paul W. Medical device with antimicrobial layer
US20060105018A1 (en) 2004-11-17 2006-05-18 Epstein Samuel J Therapeutic driving layer for a medical device
US20050112273A1 (en) * 2003-05-19 2005-05-26 Stenzel Eric B. Method of improving the quality and performance of a coating on a coated medical device using a solvent to reflow the coating
US7112216B2 (en) 2003-05-28 2006-09-26 Boston Scientific Scimed, Inc. Stent with tapered flexibility
US8021418B2 (en) * 2003-06-19 2011-09-20 Boston Scientific Scimed, Inc. Sandwiched radiopaque marker on covered stent
US7131993B2 (en) * 2003-06-25 2006-11-07 Boston Scientific Scimed, Inc. Varying circumferential spanned connectors in a stent
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7662328B2 (en) * 2003-09-02 2010-02-16 Boston Scientific Scimed, Inc. Proximal guidewire port
US7758510B2 (en) 2003-09-19 2010-07-20 Flowcardia, Inc. Connector for securing ultrasound catheter to transducer
US8636714B2 (en) * 2003-09-22 2014-01-28 Boston Scientific Scimed, Inc. Microcatheter with sleeved guidewire port
WO2005033198A1 (en) * 2003-10-07 2005-04-14 Coloplast A/S A composition useful as an adhesive and use of such a composition
US20050087520A1 (en) * 2003-10-28 2005-04-28 Lixiao Wang Method and apparatus for selective ablation of coatings from medical devices
US7901770B2 (en) * 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US8014849B2 (en) 2003-11-21 2011-09-06 Stryker Corporation Rotational markers
US8157855B2 (en) * 2003-12-05 2012-04-17 Boston Scientific Scimed, Inc. Detachable segment stent
US20050149072A1 (en) * 2003-12-31 2005-07-07 Devries Robert B. Devices and methods for tissue invagination
US7534495B2 (en) * 2004-01-29 2009-05-19 Boston Scientific Scimed, Inc. Lubricious composition
US7306677B2 (en) * 2004-01-30 2007-12-11 Boston Scientific Corporation Clamping fixture for coating stents, system using the fixture, and method of using the fixture
US7241344B2 (en) 2004-02-10 2007-07-10 Boston Scientific Scimed, Inc. Apparatus and method for electrostatic spray coating of medical devices
US20050181116A1 (en) * 2004-02-18 2005-08-18 Rob Worsham Method for coating a medical device using a matrix assisted pulsed-laser evaporation technique and associated system and medical device
US20050181141A1 (en) * 2004-02-18 2005-08-18 Aiden Flanagan Laser-induced explosive vaporization coating method, associated system, and device made by the method
US20050188921A1 (en) * 2004-02-27 2005-09-01 Anthony Malone Matrix assisted pulsed-laser evaporation technique for coating a medical device and associated system and medical device
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7371424B2 (en) * 2004-04-14 2008-05-13 Boston Scientific Scimed, Inc. Method and apparatus for coating a medical device using a coating head
US20050238870A1 (en) * 2004-04-22 2005-10-27 Marcia Buiser Embolization
US8394338B2 (en) * 2004-04-26 2013-03-12 Roche Diagnostics Operations, Inc. Process for hydrophilizing surfaces of fluidic components and systems
EP1591778A1 (en) 2004-04-26 2005-11-02 Roche Diagnostics GmbH Electrochemical gas sensor with hydrophilic membrane coating
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US20050278017A1 (en) * 2004-06-09 2005-12-15 Scimed Life Systems, Inc. Overlapped stents for scaffolding, flexibility and MRI compatibility
US7976557B2 (en) * 2004-06-23 2011-07-12 Boston Scientific Scimed, Inc. Cutting balloon and process
JP2006020827A (en) * 2004-07-08 2006-01-26 Yoshimoto Katsura Condom and manufacturing method therefor
US20060034884A1 (en) * 2004-08-10 2006-02-16 Stenzel Eric B Coated medical device having an increased coating surface area
US20060036233A1 (en) * 2004-08-12 2006-02-16 Scimed Life Systems, Inc. Catheter incorporating a guidewire exit ramp
US7765670B2 (en) * 2004-08-13 2010-08-03 Boston Scientific Scimed, Inc. Method to simultaneously load and cover self expanding stents
US7540852B2 (en) * 2004-08-26 2009-06-02 Flowcardia, Inc. Ultrasound catheter devices and methods
US7763067B2 (en) 2004-09-01 2010-07-27 C. R. Bard, Inc. Stent and method for manufacturing the stent
DK1809345T3 (en) 2004-10-07 2009-07-13 Coloplast As Medical device with a wetted hydrophilic coating
US20060083859A1 (en) 2004-10-20 2006-04-20 Todd Robida Magnetic levitation system for coating a device, a method of using the system, and device made by the system
US8066726B2 (en) * 2004-11-23 2011-11-29 Boston Scientific Scimed, Inc. Serpentine cutting blade for cutting balloon
CA2589150C (en) 2004-11-29 2013-05-28 Dsm Ip Assets B.V. Method for reducing the amount of migrateables of polymer coatings
US8425550B2 (en) * 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US20060127443A1 (en) * 2004-12-09 2006-06-15 Helmus Michael N Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery
US20060124466A1 (en) * 2004-12-09 2006-06-15 Scimed Life Systems, Inc. Method and apparatus for coating a medical device by electroplating
US8221343B2 (en) 2005-01-20 2012-07-17 Flowcardia, Inc. Vibrational catheter devices and methods for making same
US7517338B2 (en) 2005-01-21 2009-04-14 Boston Scientific Scimed, Inc. Delivery of therapeutic through multiple delivery members
US8221824B2 (en) * 2005-02-03 2012-07-17 Boston Scientific Scimed, Inc. Deforming surface of drug eluting coating to alter drug release profile of a medical device
US20060182907A1 (en) * 2005-02-11 2006-08-17 Boston Scientific Scimed, Inc. Novel microfibrillar reinforced polymer-polymer composites for use in medical devices
US7727555B2 (en) * 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) * 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7452501B2 (en) * 2005-03-03 2008-11-18 Icon Medical Corp. Metal alloy for a stent
US7686788B2 (en) 2005-03-03 2010-03-30 Boston Scientific Scimed, Inc. Catheter having a distal drug delivery unit and method of using same
JP5335244B2 (en) 2005-03-03 2013-11-06 アイコン メディカル コーポレーション Medical member using improved metal alloy
US9107899B2 (en) 2005-03-03 2015-08-18 Icon Medical Corporation Metal alloys for medical devices
US7540995B2 (en) * 2005-03-03 2009-06-02 Icon Medical Corp. Process for forming an improved metal alloy stent
US20060240060A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240059A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious eluting polymer blend and coating made from the same
US20060241000A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240253A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Guidewire and tube with lubricious coating
US7963287B2 (en) * 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US20060247674A1 (en) * 2005-04-29 2006-11-02 Roman Ricardo D String cutting balloon
PL1888127T3 (en) 2005-05-02 2010-07-30 Coloplast As A method for sterilising a medical device having a hydrophilic coating
US20070004973A1 (en) * 2005-06-15 2007-01-04 Tan Sharon M L Tissue treatment methods
US9463426B2 (en) * 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US20070038176A1 (en) * 2005-07-05 2007-02-15 Jan Weber Medical devices with machined layers for controlled communications with underlying regions
US9101949B2 (en) * 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US20070031611A1 (en) * 2005-08-04 2007-02-08 Babaev Eilaz P Ultrasound medical stent coating method and device
US7896539B2 (en) * 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
GB0517085D0 (en) * 2005-08-19 2005-09-28 Angiomed Ag Polymer prosthesis
US20070083219A1 (en) * 2005-10-12 2007-04-12 Buiser Marcia S Embolic coil introducer sheath locking mechanisms
US8007509B2 (en) * 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
JP2009518479A (en) * 2005-12-09 2009-05-07 ディーエスエム アイピー アセッツ ビー.ブイ. Hydrophilic coating containing polyelectrolyte
US20070142859A1 (en) * 2005-12-19 2007-06-21 Boston Scientific Scimed, Inc. Embolic coils
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) * 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US20070142560A1 (en) * 2005-12-21 2007-06-21 Young-Ho Song Block copolymer particles
US7501179B2 (en) * 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US7947368B2 (en) * 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
EP1988941A2 (en) 2006-01-31 2008-11-12 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
CA2637883C (en) * 2006-01-31 2015-07-07 Regents Of The University Of Minnesota Electrospray coating of objects
US8089029B2 (en) * 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
EP2289573B1 (en) 2006-02-01 2016-10-26 Hollister Incorporated Methods of applying a hydrophilic coating to a substrate, and substrates having a hydrophilic coating
CA2640234C (en) 2006-02-14 2017-01-03 Angiomed Gmbh & Co. Medizintechnik Kg Highly flexible stent and method of manufacture
US20070224235A1 (en) * 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8348991B2 (en) * 2006-03-29 2013-01-08 Boston Scientific Scimed, Inc. Stent with overlap and high expansion
US9282984B2 (en) * 2006-04-05 2016-03-15 Flowcardia, Inc. Therapeutic ultrasound system
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US20070264303A1 (en) * 2006-05-12 2007-11-15 Liliana Atanasoska Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent
GB0609841D0 (en) 2006-05-17 2006-06-28 Angiomed Ag Bend-capable tubular prosthesis
GB0609911D0 (en) 2006-05-18 2006-06-28 Angiomed Ag Bend-capable stent prosthesis
US8097291B2 (en) * 2006-06-05 2012-01-17 Boston Scientific Scimed, Inc. Methods for coating workpieces
US20070299461A1 (en) * 2006-06-21 2007-12-27 Boston Scientific Scimed, Inc. Embolic coils and related components, systems, and methods
US20070298069A1 (en) * 2006-06-26 2007-12-27 Boston Scientific Scimed, Inc. Medical devices for release of low solubility therapeutic agents
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
CA2655793A1 (en) * 2006-06-29 2008-01-03 Boston Scientific Limited Medical devices with selective coating
US9265865B2 (en) * 2006-06-30 2016-02-23 Boston Scientific Scimed, Inc. Stent having time-release indicator
KR20090045916A (en) * 2006-07-03 2009-05-08 헤모텍 아게 Manufacture, method and use of drug-eluting medical devices for permanently keeping blood vessels open
US7709046B1 (en) 2006-07-12 2010-05-04 Medi-Solve Coatings, Llc. Medical devices comprising non cross-linked, thin and flexible aqueous coatings, and methods related thereto
WO2008008291A2 (en) * 2006-07-13 2008-01-17 Icon Medical Corp. Stent
JP2009545407A (en) * 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド,インコーポレイテッド End prosthesis with 3D decomposition control
GB0616579D0 (en) 2006-08-21 2006-09-27 Angiomed Ag Self-expanding stent
GB0616999D0 (en) * 2006-08-29 2006-10-04 Angiomed Ag Annular mesh
US8500793B2 (en) * 2006-09-07 2013-08-06 C. R. Bard, Inc. Helical implant having different ends
US20080065196A1 (en) 2006-09-12 2008-03-13 Michael Wayne Davis Intra-Columnar Cell Features to Improve Drug Distribution and Scaffolding of a Stent
US7988720B2 (en) 2006-09-12 2011-08-02 Boston Scientific Scimed, Inc. Longitudinally flexible expandable stent
US8828546B2 (en) * 2006-09-13 2014-09-09 Dsm Ip Assets B.V. Coated medical device
JP2010503737A (en) * 2006-09-13 2010-02-04 ディーエスエム アイピー アセッツ ビー.ブイ. Antibacterial hydrophilic coating containing metallic silver particles
JP2010503469A (en) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド Medical device having drug-eluting film
WO2008034047A2 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Endoprosthesis with adjustable surface features
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
JP2010503489A (en) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド Biodegradable endoprosthesis and method for producing the same
DE602007011114D1 (en) * 2006-09-15 2011-01-20 Boston Scient Scimed Inc BIODEGRADABLE ENDOPROTHESIS WITH BIOSTABILES INORGANIC LAYERS
WO2008034066A1 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
WO2008034030A2 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Magnetized bioerodible endoprosthesis
WO2008036548A2 (en) 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
WO2008036554A2 (en) * 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
EP2063811A4 (en) 2006-09-18 2014-07-23 Bard Inc C R Single layer eptfe and discrete bio-resorbable rings
US20080069858A1 (en) * 2006-09-20 2008-03-20 Boston Scientific Scimed, Inc. Medical devices having biodegradable polymeric regions with overlying hard, thin layers
WO2008039319A2 (en) * 2006-09-25 2008-04-03 Boston Scientific Scimed, Inc. Injection of therapeutic into porous regions of a medical device
WO2008045184A1 (en) * 2006-10-05 2008-04-17 Boston Scientific Limited Polymer-free coatings for medical devices formed by plasma electrolytic deposition
US20080097577A1 (en) * 2006-10-20 2008-04-24 Boston Scientific Scimed, Inc. Medical device hydrogen surface treatment by electrochemical reduction
WO2008051344A2 (en) * 2006-10-25 2008-05-02 Boston Scientific Limited Method and apparatus for coating a medical device by electroless plating
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US8246643B2 (en) * 2006-11-07 2012-08-21 Flowcardia, Inc. Ultrasound catheter having improved distal end
US7981150B2 (en) * 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
GB0622465D0 (en) 2006-11-10 2006-12-20 Angiomed Ag Stent
GB0624419D0 (en) * 2006-12-06 2007-01-17 Angiomed Ag Stenting ring with marker
US9040816B2 (en) * 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
US20080142616A1 (en) * 2006-12-15 2008-06-19 Bacoustics Llc Method of Producing a Directed Spray
US20080145658A1 (en) * 2006-12-15 2008-06-19 Boston Scientific Scimed, Inc. Freeze Thaw Methods For Making Polymer Particles
ES2506144T3 (en) 2006-12-28 2014-10-13 Boston Scientific Limited Bioerodible endoprosthesis and their manufacturing procedure
US8114466B2 (en) * 2007-01-03 2012-02-14 Boston Scientific Scimed, Inc. Methods of applying coating to the inside surface of a stent
RU2447901C2 (en) * 2007-01-21 2012-04-20 Хемотек Аг Medical device for treating lumen obturations and preventing threatening recurrent obturations
EP2121106A2 (en) * 2007-01-30 2009-11-25 Boston Scientific Limited Local delivery of therapeutic agent to heart valves
EP4005537A1 (en) 2007-02-12 2022-06-01 C.R. Bard Inc. Highly flexible stent and method of manufacture
US8333799B2 (en) * 2007-02-12 2012-12-18 C. R. Bard, Inc. Highly flexible stent and method of manufacture
JP5587611B2 (en) * 2007-02-28 2014-09-10 ディーエスエム アイピー アセッツ ビー.ブイ. Hydrophilic coating
MX2009009145A (en) * 2007-02-28 2009-09-03 Dsm Ip Assets Bv Hydrophilic coating.
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US20080234672A1 (en) * 2007-03-20 2008-09-25 Tyco Healthcare Goup Lp Non-stick surface coated electrodes and method for manufacturing same
GB0706499D0 (en) 2007-04-03 2007-05-09 Angiomed Ag Bendable stent
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US20080251391A1 (en) 2007-04-12 2008-10-16 Boston Scientific Scimed, Inc. Methods and systems for applying therapeutic agent to a medical device
US8173200B2 (en) * 2007-05-02 2012-05-08 Boston Scientific Scimed, Inc. Selective application of therapeutic agent to a medical device
US7976915B2 (en) * 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8398702B2 (en) * 2007-06-29 2013-03-19 Boston Scientific Scimed, Inc. Molybdenum endoprostheses
US9192697B2 (en) * 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US7942926B2 (en) * 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) * 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
US7604662B2 (en) 2007-07-13 2009-10-20 Boston Scientific Scimed, Inc. Endoprostheses containing boride intermetallic phases
WO2009012353A2 (en) 2007-07-19 2009-01-22 Boston Scientific Limited Endoprosthesis having a non-fouling surface
US8128599B2 (en) 2007-07-20 2012-03-06 Tyco Healthcare Group Lp Lubricious coatings
US8815273B2 (en) * 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) * 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (en) * 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド Coating for medical devices with large surface area
GB0717481D0 (en) 2007-09-07 2007-10-17 Angiomed Ag Self-expansible stent with radiopaque markers
US8052745B2 (en) * 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090118809A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Endoprosthesis with porous reservoir and non-polymer diffusion layer
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8216632B2 (en) * 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) * 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US20090118813A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Nano-patterned implant surfaces
US20090118812A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
US8378011B2 (en) * 2007-12-27 2013-02-19 Boston Scientific Scimed, Inc. Enhanced durability of hydrophilic coatings
WO2009111716A1 (en) * 2008-03-06 2009-09-11 Boston Scientific Scimed, Inc. Balloon catheter devices with sheath covering
US20110059874A1 (en) * 2008-03-12 2011-03-10 Marnix Rooijmans Hydrophilic coating
US9039748B2 (en) * 2008-04-07 2015-05-26 Abbott Cardiovascular Systems Inc. Method of securing a medical device onto a balloon and system thereof
EP2271380B1 (en) 2008-04-22 2013-03-20 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
CA2727478A1 (en) * 2008-06-13 2009-12-17 Xy, Llc Lubricious microfluidic flow path system
WO2010003419A2 (en) 2008-06-16 2010-01-14 Coloplast A/S Buffered swelling media for radiation sterilized hydrophilic coatings
EP2303350A2 (en) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprosthesis coating
EP2297217B1 (en) * 2008-07-07 2021-10-20 Hyalex Orthopaedics, Inc. Hydrophilic interpenetrating polymer networks derived from hydrophobic polymers
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
CN102159261A (en) * 2008-07-09 2011-08-17 格兰特阿德勒公司 Needle for subcutaneous port
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
AU2009279716A1 (en) * 2008-08-05 2010-02-11 Biomimedica, Inc Polyurethane-grafted hydrogels
DE102008039810B3 (en) * 2008-08-25 2010-04-08 Ekf - Diagnostic Gmbh Disposable microcuvette for determination of hemoglobin content in whole blood
US8114153B2 (en) * 2008-09-05 2012-02-14 Boston Scientific Scimed, Inc. Endoprostheses
GB0816365D0 (en) * 2008-09-08 2008-10-15 Univ Belfast Polymeric material
US20100082096A1 (en) * 2008-09-30 2010-04-01 Boston Scientific Scimed, Inc. Tailored Luminal & Abluminal Drug Elution
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8231980B2 (en) * 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
EP2403546A2 (en) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) * 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US11219706B2 (en) 2009-03-11 2022-01-11 Arrow International Llc Enhanced formulations for coating medical devices
US20100274352A1 (en) * 2009-04-24 2010-10-28 Boston Scientific Scrimed, Inc. Endoprosthesis with Selective Drug Coatings
US8287937B2 (en) * 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8226566B2 (en) * 2009-06-12 2012-07-24 Flowcardia, Inc. Device and method for vascular re-entry
EP3064230B1 (en) 2009-07-10 2019-04-10 Boston Scientific Scimed, Inc. Use of nanocrystals for a drug delivery balloon
EP2453938B1 (en) * 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
WO2011028419A1 (en) * 2009-08-27 2011-03-10 Boston Scientific Scimed, Inc. Balloon catheter devices with drug-coated sheath
US8226657B2 (en) 2009-11-10 2012-07-24 Carefusion 207, Inc. Systems and methods for vertebral or other bone structure height restoration and stabilization
US8894658B2 (en) 2009-11-10 2014-11-25 Carefusion 2200, Inc. Apparatus and method for stylet-guided vertebral augmentation
US9095393B2 (en) 2012-05-30 2015-08-04 Carefusion 2200, Inc. Method for balloon-aided vertebral augmentation
EP2501431B1 (en) 2009-11-19 2020-01-08 Wellinq Medical B.V. Narrow profile composition-releasing expandable medical balloon catheter
RU2012129844A (en) 2009-12-21 2014-01-27 Колопласт А/С WETING MEDIA WITH LOW-MOLECULAR MULTI-ATOMIC ALCOHOL AND BUFFER
WO2011082227A1 (en) * 2009-12-29 2011-07-07 Boston Scientific Scimed, Inc. High strength low opening pressure stent design
US20110160645A1 (en) * 2009-12-31 2011-06-30 Boston Scientific Scimed, Inc. Cryo Activated Drug Delivery and Cutting Balloons
US20110200828A1 (en) * 2010-02-16 2011-08-18 Biocoat Incorporated Hydrophilic coatings for medical devices
US8398916B2 (en) 2010-03-04 2013-03-19 Icon Medical Corp. Method for forming a tubular medical device
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US20110238153A1 (en) * 2010-03-26 2011-09-29 Boston Scientific Scimed, Inc. Endoprostheses
JP5806289B2 (en) 2010-04-06 2015-11-10 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Endoprosthesis
US8440090B2 (en) 2010-04-29 2013-05-14 Abbott Cardiovascular Systems Inc. Apparatus and method of making a variable stiffness multilayer catheter tubing
US8920490B2 (en) 2010-05-13 2014-12-30 Boston Scientific Scimed, Inc. Endoprostheses
WO2011158642A1 (en) * 2010-06-16 2011-12-22 テルモ株式会社 Method for producing medical device
BR112012032202A2 (en) 2010-06-16 2016-11-22 Dsm Ip Assets Bv coating formulation for the preparation of a hydrophilic coating.
EP2409766A1 (en) 2010-07-23 2012-01-25 F. Hoffmann-La Roche AG Method for hydrophilising surfaces of fluid components and objects containing such components
TWI707926B (en) 2010-07-30 2020-10-21 瑞士商愛爾康公司 Readily-usable silicone hydrogel contact lenses
EP2611476B1 (en) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
JP2014508559A (en) 2010-12-30 2014-04-10 ボストン サイエンティフィック サイムド,インコーポレイテッド Multi-stage open stent design
KR101966263B1 (en) 2011-01-19 2019-04-08 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Slippery surfaces with high pressure stability, optical transparency, and self-healing characteristics
CN103703085B (en) 2011-01-19 2016-09-28 哈佛学院院长等 Smooth fluid injection porous surface and its biological applications
US8790388B2 (en) 2011-03-03 2014-07-29 Boston Scientific Scimed, Inc. Stent with reduced profile
WO2012118526A1 (en) 2011-03-03 2012-09-07 Boston Scientific Scimed, Inc. Low strain high strength stent
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
AU2012319183A1 (en) 2011-10-03 2014-05-22 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
WO2013055604A1 (en) 2011-10-11 2013-04-18 Boston Scientific Scimed, Inc. Recapture sheath
JP6017572B2 (en) 2011-10-12 2016-11-02 ノバルティス アーゲー Method for producing UV-absorbing ophthalmic lens by coating
ES2705747T3 (en) 2011-11-09 2019-03-26 Arrow Int Inc New improved formulations for coating medical devices
WO2013109269A1 (en) 2012-01-18 2013-07-25 Bard Peripheral Vascular, Inc. Vascular re-entry device
RU2627390C2 (en) 2012-01-18 2017-08-08 Сурмодикс, Инк. Sliding coating for medical devices with a small quantity of microparticles
JP5923313B2 (en) * 2012-01-23 2016-05-24 テルモ株式会社 Medical device and manufacturing method thereof
US9220584B2 (en) 2012-03-30 2015-12-29 Abbott Cardiovascular Systems Inc. Treatment of diabetic patients with a stent and locally administered adjunctive therapy
AU2013289879B2 (en) * 2012-07-12 2017-04-06 President And Fellows Of Harvard College Slippery self-lubricating polymer surfaces
EP3895632A1 (en) 2012-08-02 2021-10-20 Bard Peripheral Vascular, Inc. Ultrasound catheter system
US9901715B2 (en) * 2012-09-05 2018-02-27 W. L. Gore Associates, Inc. Retractable sheath devices, systems, and methods
WO2014095690A1 (en) 2012-12-17 2014-06-26 Novartis Ag Method for making improved uv-absorbing ophthalmic lenses
US11850331B2 (en) 2013-03-11 2023-12-26 Teleflex Medical Incorporated Devices with anti-thrombogenic and anti-microbial treatment
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
CN105979978A (en) * 2013-12-30 2016-09-28 波士顿科学国际有限公司 Functionalized Lubricious Medical Device Coatings
BR112016030273A8 (en) 2014-06-24 2021-05-18 Icon Medical Corp medical device and method of forming said device
US20150374485A1 (en) 2014-06-27 2015-12-31 Cordis Corporation Targeted perforations in endovascular device
US9579427B2 (en) 2014-06-28 2017-02-28 Cordis Corporation Thin-film composite retrievable endovascular devices and method of use
EP3186070B1 (en) 2014-08-26 2019-09-25 Novartis AG Method for applying stable coating on silicone hydrogel contact lenses
CN104398338B (en) * 2014-12-18 2016-08-17 常熟市亨利医疗器械有限公司 Intraocular lens implanting forceps
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
EP3391101B1 (en) 2015-12-15 2020-07-08 Alcon Inc. Method for applying stable coating on silicone hydrogel contact lenses
US11174447B2 (en) * 2015-12-29 2021-11-16 Surmodics, Inc. Lubricious coatings with surface salt groups
US11766506B2 (en) 2016-03-04 2023-09-26 Mirus Llc Stent device for spinal fusion
WO2017168190A1 (en) 2016-03-29 2017-10-05 CARDINAL HEALTH SWITZERLAND 515 GmbH Contracting stent with bioresorbable struts
HUE058354T2 (en) 2016-07-14 2022-07-28 Hollister Inc Hygienic medical devices having hydrophilic coating and methods of forming the same
US20180140321A1 (en) 2016-11-23 2018-05-24 C. R. Bard, Inc. Catheter With Retractable Sheath And Methods Thereof
US11596726B2 (en) 2016-12-17 2023-03-07 C.R. Bard, Inc. Ultrasound devices for removing clots from catheters and related methods
US10758256B2 (en) 2016-12-22 2020-09-01 C. R. Bard, Inc. Ultrasonic endovascular catheter
US10905578B2 (en) 2017-02-02 2021-02-02 C. R. Bard, Inc. Short stent
US10582983B2 (en) 2017-02-06 2020-03-10 C. R. Bard, Inc. Ultrasonic endovascular catheter with a controllable sheath
US11029446B2 (en) 2017-12-13 2021-06-08 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
US11359156B2 (en) 2019-10-21 2022-06-14 Biocoat, Inc. UV cure basecoatings for medical devices

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL188891B (en) * 1954-07-01 Sandoz Ag PHARMACEUTICAL PREPARATION WITH BLOOD PRESSURE LOWERING ACTION CONTAINING CO-DERGOCRIN AND ANOTHER ACTIVE MATERIAL.
US3663288A (en) * 1969-09-04 1972-05-16 American Cyanamid Co Physiologically acceptible elastomeric article
US3642943A (en) * 1970-07-08 1972-02-15 Lord Corp Acrylic urethane composition of acrylic polymer with pendant isocyanate groups and isocyanate containing urethane prepolymer
SE425372B (en) * 1977-07-18 1982-09-27 Ird Biomaterial Ab SET TO HEPARINIZE AN ELECTRICALLY CHARGED SURFACE ON A MEDICAL ARTICLE INTENDED TO CONTACT WITH BLOOD AND MEDICINES TO PERFORM THE SET
CH636527A5 (en) * 1978-10-06 1983-06-15 Intermedicat Gmbh METHOD OF MANUFACTURING AN ANTI-THROMBIC IN-HABITATION CATHETER WITH NEGATIVELY CHARGED SURFACE.
US4479795A (en) * 1979-06-29 1984-10-30 The Procter & Gamble Company Antimicrobial polymer compositions
US4373009A (en) * 1981-05-18 1983-02-08 International Silicone Corporation Method of forming a hydrophilic coating on a substrate
DE3125569A1 (en) * 1981-06-30 1983-01-20 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING COVERS
US4773901A (en) * 1981-12-31 1988-09-27 C. R. Bard, Inc. Catheter with selectively rigidified portion
US4526579A (en) * 1983-06-17 1985-07-02 Pfizer Inc. Method for graft copolymerization to natural rubber articles
AU566085B2 (en) * 1984-06-04 1987-10-08 Terumo Kabushiki Kaisha Medical instrument with surface treatment
JPS6145775A (en) * 1984-08-07 1986-03-05 テルモ株式会社 Medical tube guide and its production
US4642242A (en) * 1985-04-01 1987-02-10 Becton, Dickinson And Company Permanently bonded antithrombogenic polyurethane surface
CH665954A5 (en) * 1985-07-08 1988-06-30 Battelle Memorial Institute SUBSTRATE WITH A SURFACE OF ANTITHROMBOGENIC ACTIVITY.
SE8504501D0 (en) * 1985-09-30 1985-09-30 Astra Meditec Ab METHOD OF FORMING AN IMPROVED HYDROPHILIC COATING ON A POLYMER SURFACE
US4729914A (en) * 1985-12-30 1988-03-08 Tyndale Plains-Hunter Ltd. Hydrophilic coating and substrate coated therewith
JPS63238170A (en) * 1985-12-30 1988-10-04 タインデイル・プレインズ−ハンタ−・リミテツド Article coated with hydrophilic film

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