CA2004043A1 - Stabilization of leukocytes - Google Patents

Stabilization of leukocytes

Info

Publication number
CA2004043A1
CA2004043A1 CA2004043A CA2004043A CA2004043A1 CA 2004043 A1 CA2004043 A1 CA 2004043A1 CA 2004043 A CA2004043 A CA 2004043A CA 2004043 A CA2004043 A CA 2004043A CA 2004043 A1 CA2004043 A1 CA 2004043A1
Authority
CA
Canada
Prior art keywords
leukocytes
stabilization
nucleosides
suspending
preservation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2004043A
Other languages
French (fr)
Other versions
CA2004043C (en
Inventor
Bernard M. Babior
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of CA2004043A1 publication Critical patent/CA2004043A1/en
Application granted granted Critical
Publication of CA2004043C publication Critical patent/CA2004043C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes

Abstract

Preservation of leukocytes by suspending in storage medium containing modified fluid gelatin, plasma, and a non-toxic buffer. Preferred additives include heterocyclic bases which occur in nucleic acids, or nucleosides or nucleotides containing the same.
CA002004043A 1988-11-29 1989-11-28 Stabilization of leukocytes Expired - Fee Related CA2004043C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/277,256 US4923797A (en) 1988-11-29 1988-11-29 Stabilization of leukocytes
US07/277,256 1988-11-29

Publications (2)

Publication Number Publication Date
CA2004043A1 true CA2004043A1 (en) 1990-05-29
CA2004043C CA2004043C (en) 1999-09-28

Family

ID=23060081

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002004043A Expired - Fee Related CA2004043C (en) 1988-11-29 1989-11-28 Stabilization of leukocytes

Country Status (3)

Country Link
US (2) US4923797A (en)
CA (1) CA2004043C (en)
WO (1) WO1990006053A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923797A (en) * 1988-11-29 1990-05-08 President & Fellows Of Harvard College Stabilization of leukocytes
WO1992002133A1 (en) * 1990-08-10 1992-02-20 Analytical Control Systems, Inc. Improved diagnostic and therapeutic compositions
EP1002538A3 (en) * 1992-06-25 2000-07-19 SCHEER, David Stem cell and lymphocyte storage
GB2314843A (en) * 1993-07-05 1998-01-14 North Gen Hospital Nhs Trust Whole blood comprising a stabilised leucocyte preparation
US6415201B1 (en) * 1998-04-08 2002-07-02 Andre Lefesvre Process and system for management of batches of components of the haematopoietic system for deferred use
GB0031065D0 (en) * 2000-12-20 2001-01-31 Univ Cardiff Preservation of cells
WO2010003037A2 (en) * 2008-07-03 2010-01-07 Sierra Molecular Corporation Compositions, systems, and methods for stabilization of a cell and/or macromolecule
AU2012240016B2 (en) 2011-04-07 2016-11-10 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
US9089479B2 (en) * 2011-05-03 2015-07-28 Fenwal, Inc. Medium, solutions and methods for the washing, culturing and storage of white blood cells

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3874384A (en) * 1971-11-01 1975-04-01 American Hospital Supply Corp Improved blood storage unit and method of storing blood
JPS56139419A (en) * 1980-03-31 1981-10-30 Kuraray Co Ltd Erythrocytic preservative and erythrocytic pharmaceutical for preservation
US4558032A (en) * 1981-12-31 1985-12-10 Neomed Inc. Synthetic whole blood substitute and a method of making the same
US4539204A (en) * 1982-10-29 1985-09-03 Neomed Inc. Gelatin based synthetic blood and a method of making the same
US4596788A (en) * 1983-02-07 1986-06-24 Neomed, Inc. Gelatin and lecithin based synthetic whole blood and a method of making the same
US4471051A (en) * 1983-06-13 1984-09-11 New England Medical Center Hospitals, Inc. Stabilization of neutrophils and platelets
US4663058A (en) * 1983-10-11 1987-05-05 E. I. Du Pont De Nemours And Company Process for continuous separation of leukocyte/platelet-enriched fraction from whole blood
US4639373A (en) * 1984-11-29 1987-01-27 New England Medical Center Hospitals, Inc. Stabilization of granulocytes
US5211960A (en) * 1988-11-29 1993-05-18 Scripps Clinic And Research Foundation Stabilization of leukocytes
US4923797A (en) * 1988-11-29 1990-05-08 President & Fellows Of Harvard College Stabilization of leukocytes

Also Published As

Publication number Publication date
CA2004043C (en) 1999-09-28
US4923797A (en) 1990-05-08
WO1990006053A1 (en) 1990-06-14
US5369001A (en) 1994-11-29

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