CA2000543A1 - Bidirectional helical electrode for nerve stimulation - Google Patents

Bidirectional helical electrode for nerve stimulation

Info

Publication number
CA2000543A1
CA2000543A1 CA2000543A CA2000543A CA2000543A1 CA 2000543 A1 CA2000543 A1 CA 2000543A1 CA 2000543 A CA2000543 A CA 2000543A CA 2000543 A CA2000543 A CA 2000543A CA 2000543 A1 CA2000543 A1 CA 2000543A1
Authority
CA
Canada
Prior art keywords
nerve
assembly
helical portions
nerve stimulation
bidirectional helical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2000543A
Other languages
French (fr)
Other versions
CA2000543C (en
Inventor
Leo A. Bullara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huntington Medical Research Institute
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2000543A1 publication Critical patent/CA2000543A1/en
Application granted granted Critical
Publication of CA2000543C publication Critical patent/CA2000543C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0558—Anchoring or fixation means therefor

Abstract

A circumneural electrode assembly having a pair of spaced-apart and oppositely directed helical portions which can be opened by an insertion tool to fit the assembly over a peripheral or cranial nerve. One or more conductive electrodes on the inner surfaces of the helical portions intimately contact the nerve surface to deliver electrical stimulating signals, or alternatively, to block nerve conduction or to sense evoked potentials. The surgically implanted assembly is stable in position on the nerve, and is installed with a minimum of nerve manipulation and possible resulting trauma. The assembly preserves the advantages of previously disclosed spiral electrodes, while greatly simplifying installation, particularly in a nerve which is deeply recessed in overlying muscle or arteries.
CA002000543A 1988-10-12 1989-10-12 Bidirectional helical electrode for nerve stimulation Expired - Fee Related CA2000543C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/256,702 1988-10-12
US07/256,702 US4920979A (en) 1988-10-12 1988-10-12 Bidirectional helical electrode for nerve stimulation

Publications (2)

Publication Number Publication Date
CA2000543A1 true CA2000543A1 (en) 1990-04-12
CA2000543C CA2000543C (en) 2001-02-13

Family

ID=22973253

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002000543A Expired - Fee Related CA2000543C (en) 1988-10-12 1989-10-12 Bidirectional helical electrode for nerve stimulation

Country Status (7)

Country Link
US (1) US4920979A (en)
EP (1) EP0438510B1 (en)
JP (1) JP2897778B2 (en)
AU (1) AU622733B2 (en)
CA (1) CA2000543C (en)
DE (1) DE68927057T2 (en)
WO (1) WO1990003824A1 (en)

Families Citing this family (337)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876425A (en) * 1989-09-22 1999-03-02 Advanced Bionics Corporation Power control loop for implantable tissue stimulator
US5603726A (en) * 1989-09-22 1997-02-18 Alfred E. Mann Foundation For Scientific Research Multichannel cochlear implant system including wearable speech processor
US5117828A (en) * 1989-09-25 1992-06-02 Arzco Medical Electronics, Inc. Expandable esophageal catheter
US5095905A (en) * 1990-06-07 1992-03-17 Medtronic, Inc. Implantable neural electrode
US5143067A (en) * 1990-06-07 1992-09-01 Medtronic, Inc. Tool for implantable neural electrode
FR2670116B1 (en) * 1990-12-06 1998-08-21 Ethnor ELECTRODE, ESPECIALLY TEMPORARY ELECTRODE FOR THE HEART.
US5251634A (en) * 1991-05-03 1993-10-12 Cyberonics, Inc. Helical nerve electrode
US5215089A (en) * 1991-10-21 1993-06-01 Cyberonics, Inc. Electrode assembly for nerve stimulation
US5358514A (en) * 1991-12-18 1994-10-25 Alfred E. Mann Foundation For Scientific Research Implantable microdevice with self-attaching electrodes
SE9203733D0 (en) * 1992-12-11 1992-12-11 Siemens Elema Ab defibrillation
US5375594A (en) * 1993-03-29 1994-12-27 Cueva; Roberto A. Removable medical electrode system
US5505201A (en) * 1994-04-20 1996-04-09 Case Western Reserve University Implantable helical spiral cuff electrode
US5531778A (en) * 1994-09-20 1996-07-02 Cyberonics, Inc. Circumneural electrode assembly
US5487756A (en) * 1994-12-23 1996-01-30 Simon Fraser University Implantable cuff having improved closure
US5741319A (en) * 1995-01-27 1998-04-21 Medtronic, Inc. Biocompatible medical lead
WO1997045160A1 (en) 1996-05-31 1997-12-04 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
US5938596A (en) 1997-03-17 1999-08-17 Medtronic, Inc. Medical electrical lead
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US5967977A (en) * 1997-10-03 1999-10-19 Medtronic, Inc. Transesophageal medical lead
US5811206A (en) * 1997-10-31 1998-09-22 Medtronic, Inc. Feedthrough pin insulator, assembly and method for electrochemical cell
US7324851B1 (en) 1998-08-05 2008-01-29 Neurovista Corporation Closed-loop feedback-driven neuromodulation
US7242984B2 (en) 1998-08-05 2007-07-10 Neurovista Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US7231254B2 (en) 1998-08-05 2007-06-12 Bioneuronics Corporation Closed-loop feedback-driven neuromodulation
US7277758B2 (en) 1998-08-05 2007-10-02 Neurovista Corporation Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder
US9375573B2 (en) 1998-08-05 2016-06-28 Cyberonics, Inc. Systems and methods for monitoring a patient's neurological disease state
US9042988B2 (en) 1998-08-05 2015-05-26 Cyberonics, Inc. Closed-loop vagus nerve stimulation
US8762065B2 (en) 1998-08-05 2014-06-24 Cyberonics, Inc. Closed-loop feedback-driven neuromodulation
US7209787B2 (en) 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US9415222B2 (en) 1998-08-05 2016-08-16 Cyberonics, Inc. Monitoring an epilepsy disease state with a supervisory module
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US7403820B2 (en) * 1998-08-05 2008-07-22 Neurovista Corporation Closed-loop feedback-driven neuromodulation
US9113801B2 (en) 1998-08-05 2015-08-25 Cyberonics, Inc. Methods and systems for continuous EEG monitoring
DE19847446B4 (en) 1998-10-08 2010-04-22 Biotronik Gmbh & Co. Kg Nerve electrode assembly
US6702811B2 (en) 1999-04-05 2004-03-09 Medtronic, Inc. Ablation catheter assembly with radially decreasing helix and method of use
US6308105B1 (en) * 1999-07-15 2001-10-23 Medtronic Inc. Medical electrical stimulation system using an electrode assembly having opposing semi-circular arms
US6456866B1 (en) 1999-09-28 2002-09-24 Dustin Tyler Flat interface nerve electrode and a method for use
EP1257318B1 (en) * 2000-02-17 2006-12-20 Neurodan A/S Implantable system for neural sensing and nerve stimulation
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US6985774B2 (en) * 2000-09-27 2006-01-10 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US6600956B2 (en) 2001-08-21 2003-07-29 Cyberonics, Inc. Circumneural electrode assembly
US6999819B2 (en) * 2001-08-31 2006-02-14 Medtronic, Inc. Implantable medical electrical stimulation lead fixation method and apparatus
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US7697995B2 (en) * 2002-04-25 2010-04-13 Medtronic, Inc. Surgical lead paddle
US20040111139A1 (en) * 2002-12-10 2004-06-10 Mccreery Douglas B. Apparatus and methods for differential stimulation of nerve fibers
US7813809B2 (en) 2004-06-10 2010-10-12 Medtronic, Inc. Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
US7797058B2 (en) 2004-08-04 2010-09-14 Ndi Medical, Llc Devices, systems, and methods employing a molded nerve cuff electrode
DE202004021946U1 (en) 2003-09-12 2013-05-29 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
US7437197B2 (en) * 2003-10-23 2008-10-14 Medtronic, Inc. Medical lead and manufacturing method therefor
US20050111478A1 (en) * 2003-11-20 2005-05-26 International Business Machines Corporation Distributed control load shaping method and apparatus
US7450998B2 (en) * 2003-11-21 2008-11-11 Alfred E. Mann Foundation For Scientific Research Method of placing an implantable device proximate to neural/muscular tissue
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US8467875B2 (en) 2004-02-12 2013-06-18 Medtronic, Inc. Stimulation of dorsal genital nerves to treat urologic dysfunctions
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
US7162310B2 (en) 2004-05-10 2007-01-09 Pacesetter, Inc. Flat wire helix electrode used in screw-in cardiac stimulation leads
US7761167B2 (en) 2004-06-10 2010-07-20 Medtronic Urinary Solutions, Inc. Systems and methods for clinician control of stimulation systems
US9205255B2 (en) 2004-06-10 2015-12-08 Medtronic Urinary Solutions, Inc. Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
US8195304B2 (en) 2004-06-10 2012-06-05 Medtronic Urinary Solutions, Inc. Implantable systems and methods for acquisition and processing of electrical signals
US9308382B2 (en) 2004-06-10 2016-04-12 Medtronic Urinary Solutions, Inc. Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
US8165692B2 (en) 2004-06-10 2012-04-24 Medtronic Urinary Solutions, Inc. Implantable pulse generator power management
WO2006009722A2 (en) * 2004-06-17 2006-01-26 Innersea Technology, Inc. Long term bi-directional axon-electronic communication system
WO2006012050A2 (en) * 2004-06-30 2006-02-02 Cvrx, Inc. Connection structures for extra-vascular electrode lead body
US20120277839A1 (en) 2004-09-08 2012-11-01 Kramer Jeffery M Selective stimulation to modulate the sympathetic nervous system
US9205261B2 (en) 2004-09-08 2015-12-08 The Board Of Trustees Of The Leland Stanford Junior University Neurostimulation methods and systems
US20060052856A1 (en) 2004-09-08 2006-03-09 Kim Daniel H Stimulation components
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
EP2298410B1 (en) 2004-12-27 2013-10-09 The Feinstein Institute for Medical Research Treating inflammatory disorders by electrical vagus nerve stimulation
US8600521B2 (en) 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US7294108B1 (en) 2005-01-27 2007-11-13 Pacesetter, Inc. Cardiac event microrecorder and method for implanting same
US7561918B2 (en) 2005-01-28 2009-07-14 Cyberonics, Inc. Autocapture in a neurostimulator
US8260426B2 (en) * 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US8565867B2 (en) * 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US7454245B2 (en) 2005-01-28 2008-11-18 Cyberonics, Inc. Trained and adaptive response in a neurostimulator
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US20060259078A1 (en) 2005-05-16 2006-11-16 Imad Libbus Method and apparatus for electronically switching electrode configuration
US20060271137A1 (en) * 2005-05-25 2006-11-30 The Cleveland Clinic Foundation Apparatus and system to stimulate a nerve
US7856273B2 (en) 2005-07-28 2010-12-21 Cyberonics, Inc. Autonomic nerve stimulation to treat a gastrointestinal disorder
US20070092591A1 (en) * 2005-10-24 2007-04-26 Cyberonics, Inc. Vacuum mandrel for use in fabricating an implantable electrode
US7620455B2 (en) 2005-10-25 2009-11-17 Cyberonics, Inc. Cranial nerve stimulation to treat eating disorders
US20070100411A1 (en) * 2005-10-27 2007-05-03 Medtronic, Inc. Implantable medical electrical stimulation lead fixation method and apparatus
US8428731B2 (en) 2005-10-27 2013-04-23 Cyberonics, Inc. Sequenced therapy protocols for an implantable medical device
US8509914B2 (en) * 2005-10-28 2013-08-13 Cyberonics, Inc. Insert for implantable electrode
US8694118B2 (en) 2005-10-28 2014-04-08 Cyberonics, Inc. Variable output ramping for an implantable medical device
US8868172B2 (en) 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US20070173890A1 (en) * 2006-01-24 2007-07-26 Cyberonics, Inc. Stimulation mode adjustment for an implantable medical device
US20070173914A1 (en) * 2006-01-24 2007-07-26 Cyberonics, Inc. Self-locking electrode assembly usable with an implantable medical device
US7996079B2 (en) * 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
US7657310B2 (en) 2006-01-26 2010-02-02 Cyberonics, Inc. Treatment of reproductive endocrine disorders by vagus nerve stimulation
US7467016B2 (en) * 2006-01-27 2008-12-16 Cyberonics, Inc. Multipolar stimulation electrode with mating structures for gripping targeted tissue
US8615309B2 (en) 2006-03-29 2013-12-24 Catholic Healthcare West Microburst electrical stimulation of cranial nerves for the treatment of medical conditions
US7974706B2 (en) * 2006-03-30 2011-07-05 Boston Scientific Neuromodulation Corporation Electrode contact configurations for cuff leads
US8180462B2 (en) * 2006-04-18 2012-05-15 Cyberonics, Inc. Heat dissipation for a lead assembly
US7962220B2 (en) * 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US9480846B2 (en) 2006-05-17 2016-11-01 Medtronic Urinary Solutions, Inc. Systems and methods for patient control of stimulation systems
US20080027347A1 (en) 2006-06-23 2008-01-31 Neuro Vista Corporation, A Delaware Corporation Minimally Invasive Monitoring Methods
US8478420B2 (en) * 2006-07-12 2013-07-02 Cyberonics, Inc. Implantable medical device charge balance assessment
US20080027524A1 (en) * 2006-07-26 2008-01-31 Maschino Steven E Multi-electrode assembly for an implantable medical device
ES2560006T3 (en) 2006-10-18 2016-02-17 Vessix Vascular, Inc. Induction of desirable temperature effects on body tissue
EP2954868A1 (en) 2006-10-18 2015-12-16 Vessix Vascular, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
JP5559539B2 (en) 2006-10-18 2014-07-23 べシックス・バスキュラー・インコーポレイテッド System that induces desirable temperature effects on body tissue
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US8295934B2 (en) 2006-11-14 2012-10-23 Neurovista Corporation Systems and methods of reducing artifact in neurological stimulation systems
US9427570B2 (en) * 2006-12-06 2016-08-30 St. Jude Medical Luxembourg Holdings SMI S.A.R.L. (“SJM LUX SMI”) Expandable stimulation leads and methods of use
AU2007329252A1 (en) 2006-12-06 2008-06-12 Spinal Modulation, Inc. Hard tissue anchors and delivery devices
JP5433420B2 (en) * 2006-12-06 2014-03-05 スパイナル・モデュレーション・インコーポレイテッド Collective lead for spinal cord stimulation
AU2007329253B2 (en) 2006-12-06 2014-03-27 Spinal Modulation, Inc. Delivery devices, systems and methods for stimulating nerve tissue on multiple spinal levels
WO2008070809A2 (en) * 2006-12-06 2008-06-12 Spinal Modulation, Inc. Implantable flexible circuit leads and methods of use
US7996092B2 (en) 2007-01-16 2011-08-09 Ndi Medical, Inc. Devices, systems, and methods employing a molded nerve cuff electrode
US20080183188A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Integrated Surgical Navigational and Neuromonitoring System
US20080183068A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Integrated Visualization of Surgical Navigational and Neural Monitoring Information
US9898656B2 (en) 2007-01-25 2018-02-20 Cyberonics, Inc. Systems and methods for identifying a contra-ictal condition in a subject
US8374673B2 (en) * 2007-01-25 2013-02-12 Warsaw Orthopedic, Inc. Integrated surgical navigational and neuromonitoring system having automated surgical assistance and control
US20080183074A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Method and apparatus for coordinated display of anatomical and neuromonitoring information
US7987001B2 (en) * 2007-01-25 2011-07-26 Warsaw Orthopedic, Inc. Surgical navigational and neuromonitoring instrument
EP2124734A2 (en) * 2007-01-25 2009-12-02 NeuroVista Corporation Methods and systems for measuring a subject's susceptibility to a seizure
US7974707B2 (en) * 2007-01-26 2011-07-05 Cyberonics, Inc. Electrode assembly with fibers for a medical device
AU2008210504B2 (en) * 2007-01-29 2012-07-26 Spinal Modulation, Inc. Sutureless lead retention features
US20080183265A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Transvascular lead with proximal force relief
US20080183264A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Electrode configurations for transvascular nerve stimulation
US7917230B2 (en) * 2007-01-30 2011-03-29 Cardiac Pacemakers, Inc. Neurostimulating lead having a stent-like anchor
US20080183186A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Method and apparatus for delivering a transvascular lead
US7949409B2 (en) * 2007-01-30 2011-05-24 Cardiac Pacemakers, Inc. Dual spiral lead configurations
US8244378B2 (en) * 2007-01-30 2012-08-14 Cardiac Pacemakers, Inc. Spiral configurations for intravascular lead stability
US20080183187A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Direct delivery system for transvascular lead
US20080183255A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Side port lead delivery system
DE102007008154A1 (en) * 2007-02-19 2008-08-21 Universität Rostock Stapediusmuskelelektrode
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US7962214B2 (en) * 2007-04-26 2011-06-14 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US7869884B2 (en) 2007-04-26 2011-01-11 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US7904175B2 (en) * 2007-04-26 2011-03-08 Cyberonics, Inc. Trans-esophageal vagus nerve stimulation
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US20090012590A1 (en) * 2007-07-03 2009-01-08 Cyberonics, Inc. Neural Conductor
US9788744B2 (en) 2007-07-27 2017-10-17 Cyberonics, Inc. Systems for monitoring brain activity and patient advisory device
US7818069B2 (en) * 2007-07-27 2010-10-19 Cyberonics, Inc. Ribbon electrode
WO2009029614A1 (en) 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
WO2009048581A1 (en) * 2007-10-09 2009-04-16 Imthera Medical, Inc. System and method for neural stimulation
US8942798B2 (en) * 2007-10-26 2015-01-27 Cyberonics, Inc. Alternative operation mode for an implantable medical device based upon lead condition
US8868203B2 (en) * 2007-10-26 2014-10-21 Cyberonics, Inc. Dynamic lead condition detection for an implantable medical device
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US20090171168A1 (en) 2007-12-28 2009-07-02 Leyde Kent W Systems and Method for Recording Clinical Manifestations of a Seizure
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US11766565B2 (en) 2008-01-25 2023-09-26 Flint Hills Scientific, L.L.C. Contingent cardio-protection for epilepsy patients
US9579506B2 (en) 2008-01-25 2017-02-28 Flint Hills Scientific, L.L.C. Contingent cardio-protection for epilepsy patients
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
US9211409B2 (en) 2008-03-31 2015-12-15 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of T-cell activity
US8204603B2 (en) * 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US8473062B2 (en) * 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
EP2373378B1 (en) * 2008-10-27 2017-04-26 Spinal Modulation Inc. Selective stimulation systems and signal parameters for medical conditions
WO2010054116A1 (en) * 2008-11-10 2010-05-14 Cardiac Pacemakers, Inc. Distal end converter for a medical device lead
EP2355737B1 (en) 2008-11-17 2021-08-11 Boston Scientific Scimed, Inc. Selective accumulation of energy without knowledge of tissue topography
US8412338B2 (en) 2008-11-18 2013-04-02 Setpoint Medical Corporation Devices and methods for optimizing electrode placement for anti-inflamatory stimulation
US8515520B2 (en) 2008-12-08 2013-08-20 Medtronic Xomed, Inc. Nerve electrode
US9084551B2 (en) * 2008-12-08 2015-07-21 Medtronic Xomed, Inc. Method and system for monitoring a nerve
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
KR101685124B1 (en) 2008-12-30 2016-12-09 리서치 파운데이션 오브 더 시티 유니버시티 오브 뉴욕 Methods for reducing discomfort during electrostimulation, and compositions and apparatus therefor
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8588933B2 (en) 2009-01-09 2013-11-19 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US20100179562A1 (en) * 2009-01-14 2010-07-15 Linker Fred I Stimulation leads, delivery systems and methods of use
US9320908B2 (en) * 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US20100185249A1 (en) * 2009-01-22 2010-07-22 Wingeier Brett M Method and Devices for Adrenal Stimulation
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
AU2010229985B2 (en) 2009-03-24 2015-09-17 Spinal Modulation, Inc. Pain management with stimulation subthreshold to paresthesia
WO2010117810A1 (en) 2009-03-31 2010-10-14 Inspire Medical Systems, Inc. Percutaneous access for systems of treating sleep-related disordered breathing
US8239028B2 (en) 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US9259569B2 (en) 2009-05-15 2016-02-16 Daniel M. Brounstein Methods, systems and devices for neuromodulating spinal anatomy
US20100298916A1 (en) * 2009-05-22 2010-11-25 Pierre Rabischong Pelvic implanted neural electrode and method for implanting same
AU2010254490B2 (en) * 2009-05-26 2014-06-12 Cardiac Pacemakers, Inc. Helically formed coil for a neural cuff electrode
US8786624B2 (en) 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
CN102573986B (en) 2009-06-09 2016-01-20 赛博恩特医疗器械公司 For the nerve cuff with bag portion without wire stimulator
EP2440283B1 (en) 2009-06-09 2018-08-01 Neuronano AB Microelectrode and multiple microelectrodes comprising means for releasing drugs into the tissue
SE0901166A1 (en) * 2009-09-10 2011-03-11 Cathprint Ab Flexible catheter lead carrier provided with such lead carrier
US9327110B2 (en) 2009-10-27 2016-05-03 St. Jude Medical Luxembourg Holdings SMI S.A.R.L. (“SJM LUX SMI”) Devices, systems and methods for the targeted treatment of movement disorders
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
WO2011079309A2 (en) 2009-12-23 2011-06-30 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
US20110264116A1 (en) * 2009-12-31 2011-10-27 Gordon Kocur Compressive Denervation Apparatus for Innervated Renal Vasculature
JP5596989B2 (en) * 2010-01-26 2014-10-01 オリンパス株式会社 Electrode system
US8606368B2 (en) * 2010-01-26 2013-12-10 Olympus Corporation Electrode unit, electrode system, electrode implanting apparatus, and electrode implanting system
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
JP2013523318A (en) 2010-04-09 2013-06-17 べシックス・バスキュラー・インコーポレイテッド Power generation and control equipment for tissue treatment
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8478428B2 (en) 2010-04-23 2013-07-02 Cyberonics, Inc. Helical electrode for nerve stimulation
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
WO2011143233A2 (en) 2010-05-10 2011-11-17 Spinal Modulation, Inc. Methods, systems and devices for reducing migration
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
CA2812004C (en) 2010-08-25 2017-04-11 Neuronano Ab Displacement resistant microelectrode, microelectrode bundle and microelectrode array
EP3002037B1 (en) 2010-09-15 2018-06-06 Cardiac Pacemakers, Inc. Automatic selection of lead configuration for a neural stimulation lead
US8965482B2 (en) 2010-09-30 2015-02-24 Nevro Corporation Systems and methods for positioning implanted devices in a patient
US8805519B2 (en) 2010-09-30 2014-08-12 Nevro Corporation Systems and methods for detecting intrathecal penetration
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
US8562523B2 (en) 2011-03-04 2013-10-22 Flint Hills Scientific, Llc Detecting, assessing and managing extreme epileptic events
US8562524B2 (en) 2011-03-04 2013-10-22 Flint Hills Scientific, Llc Detecting, assessing and managing a risk of death in epilepsy
EP2632376B1 (en) 2010-10-25 2020-02-12 Medtronic Ardian Luxembourg S.à.r.l. Catheter apparatuses having multi-electrode arrays for renal neuromodulation
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
AU2011320117B2 (en) * 2010-10-29 2016-03-03 Cvrx, Inc. Implant tool and improved electrode design for minimally invasive procedure
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
WO2012100095A1 (en) 2011-01-19 2012-07-26 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US9498162B2 (en) 2011-04-25 2016-11-22 Cyberonics, Inc. Identifying seizures using heart data from two or more windows
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
WO2012154865A2 (en) 2011-05-09 2012-11-15 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
WO2013003278A1 (en) 2011-06-28 2013-01-03 Cardiac Pacemakers, Inc. Strain relief feature for an implantable medical device lead
AU2012279403B2 (en) 2011-07-07 2015-05-28 Cardiac Pacemakers, Inc. Insulation and stability features for an implantable medical device lead
US9579030B2 (en) 2011-07-20 2017-02-28 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
US9186209B2 (en) 2011-07-22 2015-11-17 Boston Scientific Scimed, Inc. Nerve modulation system having helical guide
JP5797062B2 (en) * 2011-08-25 2015-10-21 オリンパス株式会社 Electrode placement system
WO2013055826A1 (en) 2011-10-10 2013-04-18 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
WO2013055815A1 (en) 2011-10-11 2013-04-18 Boston Scientific Scimed, Inc. Off -wall electrode device for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US10206591B2 (en) 2011-10-14 2019-02-19 Flint Hills Scientific, Llc Seizure detection methods, apparatus, and systems using an autoregression algorithm
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US20130123872A1 (en) * 2011-11-03 2013-05-16 Pacesetter, Inc. Leadless implantable medical device with dual chamber sensing functionality
CN108095821B (en) 2011-11-08 2021-05-25 波士顿科学西美德公司 Orifice renal nerve ablation
EP2779929A1 (en) 2011-11-15 2014-09-24 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US10188856B1 (en) 2011-12-07 2019-01-29 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
US9095267B2 (en) 2011-12-22 2015-08-04 Modular Bionics Inc. Neural interface device and insertion tools
CA2859989C (en) 2011-12-23 2020-03-24 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9433760B2 (en) 2011-12-28 2016-09-06 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
WO2013112920A1 (en) 2012-01-25 2013-08-01 Nevro Corporation Lead anchors and associated systems and methods
US8903509B2 (en) 2012-03-21 2014-12-02 Cardiac Pacemakers Inc. Systems and methods for stimulation of vagus nerve
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
WO2013169927A1 (en) 2012-05-08 2013-11-14 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US8888773B2 (en) 2012-05-11 2014-11-18 Medtronic Ardian Luxembourg S.A.R.L. Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods
WO2014032016A1 (en) 2012-08-24 2014-02-27 Boston Scientific Scimed, Inc. Intravascular catheter with a balloon comprising separate microporous regions
CN104780859B (en) 2012-09-17 2017-07-25 波士顿科学西美德公司 Self-positioning electrode system and method for renal regulation
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
JP6162245B2 (en) 2012-10-02 2017-07-12 カーディアック ペースメイカーズ， インコーポレイテッド Lead assembly with cuff electrode assembly
US9114250B2 (en) 2012-10-02 2015-08-25 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
CN104869930B (en) 2012-10-10 2020-12-25 波士顿科学国际有限公司 Renal neuromodulation apparatus and methods
US9308022B2 (en) 2012-12-10 2016-04-12 Nevro Corporation Lead insertion devices and associated systems and methods
US8983626B2 (en) 2012-12-28 2015-03-17 Cardiac Pacemarkers, Inc. Stimulation cuff and implantation tool
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
WO2014126857A1 (en) * 2013-02-13 2014-08-21 Cardiac Pacemakers, Inc. Cuff electrode with integrated tendril
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
AU2014237950B2 (en) 2013-03-15 2017-04-13 Boston Scientific Scimed, Inc. Control unit for use with electrode pads and a method for estimating an electrical leakage
US9827039B2 (en) 2013-03-15 2017-11-28 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9056195B2 (en) 2013-03-15 2015-06-16 Cyberonics, Inc. Optimization of cranial nerve stimulation to treat seizure disorderse during sleep
US9179974B2 (en) 2013-03-15 2015-11-10 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
JP2016523147A (en) 2013-06-21 2016-08-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Renal denervation balloon catheter with a riding-type electrode support
JP2016524949A (en) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Medical device for renal nerve ablation having a rotatable shaft
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
US9265935B2 (en) 2013-06-28 2016-02-23 Nevro Corporation Neurological stimulation lead anchors and associated systems and methods
US9833283B2 (en) 2013-07-01 2017-12-05 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
CN105377169B (en) 2013-07-11 2019-04-19 波士顿科学国际有限公司 Device and method for neuromodulation
US9925001B2 (en) 2013-07-19 2018-03-27 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
CN105473093B (en) 2013-08-22 2019-02-05 波士顿科学国际有限公司 Flexible circuit with the improved adhesion strength to renal nerve modulation sacculus
CN105555218B (en) 2013-09-04 2019-01-15 波士顿科学国际有限公司 With radio frequency (RF) foley's tube rinsed with cooling capacity
US20150073515A1 (en) 2013-09-09 2015-03-12 Medtronic Ardian Luxembourg S.a.r.I. Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
EP3043733A1 (en) 2013-09-13 2016-07-20 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
WO2015057521A1 (en) 2013-10-14 2015-04-23 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
US10166386B2 (en) * 2013-10-14 2019-01-01 The Board Of Regents Of The University Of Oklahoma Implantable electrode assembly
AU2014334574B2 (en) 2013-10-15 2017-07-06 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
US10945786B2 (en) 2013-10-18 2021-03-16 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
EP3060153A1 (en) 2013-10-25 2016-08-31 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
CN106572881B (en) 2014-02-04 2019-07-26 波士顿科学国际有限公司 Substitution of the heat sensor on bipolar electrode is placed
US10736690B2 (en) 2014-04-24 2020-08-11 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters and associated systems and methods
US9302109B2 (en) 2014-04-25 2016-04-05 Cyberonics, Inc. Cranial nerve stimulation to treat depression during sleep
US9585611B2 (en) 2014-04-25 2017-03-07 Cyberonics, Inc. Detecting seizures based on heartbeat data
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US11406833B2 (en) 2015-02-03 2022-08-09 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US20160331326A1 (en) * 2015-02-13 2016-11-17 National University Of Singapore Flexible neural strip electrodes, flexible neural ribbon electrodes and compartment based embedded nerve tissue electrode interfaces for peripheral nerves
US9789321B2 (en) 2015-04-03 2017-10-17 Nevro Corp. Couplings for implanted leads and external stimulators, and associated systems and methods
US10674914B1 (en) 2015-06-24 2020-06-09 Modular Bionics Inc. Wireless neural interface system
KR101700886B1 (en) * 2015-07-24 2017-02-01 한국과학기술연구원 Neural probe array of high performance and for minimized damage of neuron
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
WO2017127758A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10695569B2 (en) 2016-01-20 2020-06-30 Setpoint Medical Corporation Control of vagal stimulation
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10814127B2 (en) 2016-02-05 2020-10-27 Boston Scientific Neuromodulation Corporation Slotted sleeve neurostimulation device
WO2017136346A1 (en) 2016-02-05 2017-08-10 Boston Scientfic Neuromodulation Corporation Implantable optical stimulation lead
WO2017143254A1 (en) 2016-02-19 2017-08-24 Boston Scientific Neuromodulation Corporation Electrical stimulation cuff devices and systems
US10493269B2 (en) 2016-06-02 2019-12-03 Boston Scientific Neuromodulation Corporation Leads for electrostimulation of peripheral nerves and other targets
US10086192B2 (en) 2016-07-07 2018-10-02 Modular Bionics Inc. Neural interface insertion and retraction tools
EP3452163A1 (en) 2016-07-29 2019-03-13 Boston Scientific Neuromodulation Corporation Systems and methods for making and using an electrical stimulation system for peripheral nerve stimulation
US10905883B2 (en) 2016-12-02 2021-02-02 Boston Scientific Neuromodulation Corporation Methods and systems for selecting stimulation parameters for electrical stimulation devices
US10980999B2 (en) 2017-03-09 2021-04-20 Nevro Corp. Paddle leads and delivery tools, and associated systems and methods
CN111491691B (en) * 2017-07-28 2024-02-02 加尔瓦尼生物电子有限公司 Electrode device for nerve stimulation
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US11065439B1 (en) 2017-12-11 2021-07-20 Modular Bionics Inc. Conforming modular neural interface system
WO2019183054A1 (en) 2018-03-23 2019-09-26 Boston Scientific Neuromodulation Corporation Optical stimulation systems with calibration and methods of making and using
EP3768372A1 (en) 2018-03-23 2021-01-27 Boston Scientific Neuromodulation Corporation An optical stimulation system with on-demand monitoring and methods of making and using
WO2019191423A1 (en) 2018-03-29 2019-10-03 Nevro Corp. Leads having sidewall openings, and associated systems and methods
DE102018207709A1 (en) 2018-05-17 2019-11-21 Neuroloop GmbH Device for extravascular or extraneuronal attachment of a medical implant in the form of a winding cuff
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
EP3840824A1 (en) 2018-11-16 2021-06-30 Boston Scientific Neuromodulation Corporation An optical stimulation system with on-demand monitoring and methods of making
US20230026776A1 (en) * 2019-12-20 2023-01-26 Incube Labs, Llc Implantable self-closing cuff
JP2023526080A (en) 2020-05-21 2023-06-20 ザ・フェインステイン・インスティチュート・フォー・メディカル・リサーチ Systems and methods for vagus nerve stimulation
EP4168110A1 (en) 2020-09-04 2023-04-26 Boston Scientific Neuromodulation Corporation Stimulation systems with a lens arrangement for light coupling and methods of making and using

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507005A (en) * 1969-03-26 1971-05-15 Inst Medicina Farmacie Device for electrical neurostimulation for the evacuation of the neurogenic urinary bladder
US4026300A (en) * 1975-03-14 1977-05-31 Liberty Mutual Method and apparatus for interfacing to nerves
FR2525110B1 (en) * 1982-02-19 1985-07-05 Alfandari Jean Pierre CARDIAC STIMULATION DEVICE INCLUDING A SEPARATE EPICARDIAL ELECTRODE WITH A FIXING MEANS
US4590946A (en) * 1984-06-14 1986-05-27 Biomed Concepts, Inc. Surgically implantable electrode for nerve bundles
US4573481A (en) * 1984-06-25 1986-03-04 Huntington Institute Of Applied Research Implantable electrode array
US4602624A (en) * 1984-10-11 1986-07-29 Case Western Reserve University Implantable cuff, method of manufacture, and method of installation
US4750499A (en) * 1986-08-20 1988-06-14 Hoffer Joaquin A Closed-loop, implanted-sensor, functional electrical stimulation system for partial restoration of motor functions

Also Published As

Publication number Publication date
JPH04503312A (en) 1992-06-18
EP0438510B1 (en) 1996-08-28
DE68927057D1 (en) 1996-10-02
EP0438510A4 (en) 1992-08-26
WO1990003824A1 (en) 1990-04-19
EP0438510A1 (en) 1991-07-31
US4920979A (en) 1990-05-01
CA2000543C (en) 2001-02-13
AU622733B2 (en) 1992-04-16
DE68927057T2 (en) 1997-04-03
AU4488389A (en) 1990-05-01
JP2897778B2 (en) 1999-05-31

Similar Documents

Publication Publication Date Title
CA2000543A1 (en) Bidirectional helical electrode for nerve stimulation
WO1996009087A3 (en) Cardiac pacemaker with universal coating
AU1357688A (en) Ergonometric transcutaneous electrical nerve stimulator
AU7467496A (en) Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure
AU3775689A (en) Process and device for electrical stimulation of the auditory nerve
AU2874792A (en) Improved electrode assembly for nerve stimulation
AU5426890A (en) Improved transcutaneous electrical nerve stimulation (tens) device
WO2006017634A3 (en) Devices, systems, and methods employing a molded nerve cuff electrode
WO2002102455A8 (en) Miniature implantable array and stimulation system suitable for eyelid stimulation
AU577501B2 (en) Auditory stimulating system
AU8483691A (en) Verification of capture using an indifferent electrode mounted on the pacemaker connector top
WO2002017987A3 (en) Device for electrical stimulation and sensing of muscles and nerves of the intravaginal cavity
AU5578301A (en) Artificial retina device with stimulating and ground return electrodes disposed on opposite sides of the neuroretina and method of attachment
AU4641493A (en) Treatment of pain by vagal afferent stimulation
SE9202792D0 (en) ELECTRODING SYSTEM FOR PACEMAKER
CA2152049A1 (en) Telemetry system and apparatus
AU581315B2 (en) Electrical stimulation electrode
AU2438788A (en) Ramped waveform non-invasive pacemaker
CA2164850A1 (en) Wearable iontophoresis system
AU5078293A (en) Electrically programmable polarity connector for an implantable body tissue stimulator
EP0339877A3 (en) In-line pacemaker connector system
AU2003283026A1 (en) Systems and methods for treating movement disorders
AU6052686A (en) An external ear canal electrode to be placed proximate the tympanic membrane and method of stimulating/recording utilizing external ear canal electrode placed proximate the tympanic membrane
SE9800520D0 (en) Electrode for tissue stimulation
AU2399892A (en) Treatment of anxiety disorders by nerve stimulation

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed