CA1151960A

CA1151960A - Water-activated casting material

Info

Publication number: CA1151960A
Application number: CA000350339A
Authority: CA
Inventors: Shiraz A. Kathiriya; Donald C. Garwood
Original assignee: Minnesota Mining and Manufacturing Co
Current assignee: 3M Co
Priority date: 1979-09-04
Filing date: 1980-04-22
Publication date: 1983-08-16
Also published as: IT8024440A0; JPH0257940B2; ES8107017A1; ZA805451B; FR2464076A1; BR8008811A; EP0035517B1; WO1981000671A1; EP0035517A1; ATE16977T1; JPS56501198A; EP0035517A4; FR2464076B1; IT1195028B; DE3071300D1; US4502479A; ES494711A0

Abstract

ABSTRACT OF THE DISCLOSURE

An orthopedic casting material is disclosed having improved strength and porosity characteristics.
The casting material comprises a fabric which is made from a high modulus fiber and has a thickness between 0.020 and 0,045 inches and a mesh size of 20 to 200 openings per square inch. The fabric is impregnated with a reactive resin which hardens by wetting with a curing agent.

Description

jO 915,738 WATER ACTIVATED CASTING MATERIAL

The present invention pertains to the application of orthopedic casts, and in the preferred embodiment, to the application of orthopedic casts formed of moîsture~curing plastic material.
Orthopedic casts for use in the treatment of bone fractures or other conditions requiring immobilization of a body member are generally formed from a strip of fabric or scrim material impregnated with a substance which hardens into a rigid structure after the strip has been wrapped around the body member. The hardening substance traditionally used is plaster-of-paris. Plaster-of-paris casts, however, have a number of attendant disadvantages including a low strength-to-weight ratio resulting in a finished cast which is very heavy and bulky. Plaster-of-paris casts breakdown in water thus making bathing or showering difficult. Also, plaster-of-paris casts are not air-permeable and do not allow for evaporation of moisture from the skin beneath the cast. This may lead to skin irritation or infection. These disadvantages as well as many others have stimulated the search for other hardening substances having improved properties over plaster-of-paris.
Certain plastic and plastic-reinforced materials have gained wide attention as potential replacements for plaster-of-paris in orthopedic casts. Plastic casts are .J

generally much lighter than plaster-of-paris, impervious to water and provide excellent x-ray clarity. However, they have not gained broad acceptance among physicians and cast technicians due to their failure to meet certain performance requirements. A good plastic casting material must be safe to apply and non-irritating to the skin of the wearer. Thus, resins which give off toxic volatile materials or which expose the body to unsafe heat levels during application are unacceptable. A suitable resin must allow sufficient "working time'l e.g., 8 to 10 minutes, in which the wrapping is accomplished and the cast is pressed into shape. After the cast is shaped, the resin should harden rapidly, e.g., 15-30 minutes, into a rigid, high-stren~th, weight-bearin~ cast. In addition to the foregoing requirements, a good plastic casting material should provide good lamination between the fabric layers of the cast, be porous enough to allow evaporation of moisture from the skin, have good x-ray clarity, low flammability and a shelflife of at least nine months under room temperature storage conditions. A number of attempts have been made heretofore to provide a plastic casting material meeting the foregoing criteria.
A significant advance in the art is disclosed in U.S. Patent Nos. 3,421,501 and 3,881,473. The casting materials disclosed in these patents comprise a flexible fabric impregnated with an ultraviolet light curing polymer. The major disadvantage associated with this type 6~
~3--of cast material is the need for an ultraviolet light source which is unavailable in many ho.spitals and doctors' o~fices.
U.S. Patent No. 4,105,025 discloses a cast-forming bandage material comprising a substrate such as a perforated fabric or net-like structure impregnated or coated with a crystallized polyurethane polymer material. The bandage is heated to melt the polymer prior to application to the body member, The bandaqe is applied immediately or allowed to cool down to room temperature prior to application and formed into the desired shape.
Upon standing at room temperature, the polyurethane polymer crystallizes into a rigid cast. Disadvantages of this type of casting material, as well as other casting materials containing thermoplastic resins, include the necessity to heat the material prior to application and the danger of applying hot materials to the skin.
As an alternative to thermoplastic materials which are polymerized prior to use and merely softened to

2~ render them flexible enough for application to the body member, other casting materials and orthopedic applicances are known wherein the resin is cured after application to the body member. Generally, this involves exposing the resin to a second chemical reactant or catalyst. An example of such a system is a fabric or scrim material impregnated with a polyurethane prepolymer which reacts with water as the second chemical reactant to initiate 6(~

curing. The prepolymer-treated bandage is soaked in water prior to applicaion to the body memberq The wet bandage is then applied to the hody member by wrapping in much the same way as a piaster-of-paris cast is applied. The bandage hardens into a rigid structure in a matter of minutes. A paper by Lysaght and Rich describing such a casting material was presented at the 3rd Annual Meeting of the Society for Biomaterials, 9th Annual Internationa Biomaterial Symposium, New Orleans, Louisanna (1977).
These observers found that fine-woven fiberglass as the scrim material provides a cast with the highest strength-to-weight ratio and best overall feel. No specific information regarding the fiberglass fabric was disclosed.
Another casting material comprising a fabric impregnated with a water-curable polyurethane prepolymer is disclosed in German Offenlegungsschrift 26 51 089~ The essence of the invention disclosed therein resides in the use of prepolymers prepared from aromatic polyisocyanates and tertiary amine N-containing polyols. A product currently marketed in the United States under the trademark Cutter Cast~ by a subsidiary of the company owning the aforementioned German Patent Appliction comprises a dacron/cotton (65/35) fabric and a water-cured polyisocyanate prepolymer.
From the foregoing discussion, it is apparent that the prior art has discovered improved plastic casting ~51~60 materials which solve many of the problems previously associated with such materials. The polyurethane casting materials discussed immediately above are relatively safe and easy to apply to the body member. They are water-cured an~
give off little exo~herm. Additionally, the cast remains soft and moldable long enough to permit shaping into the desired configuration yet cure relatively fastto permit the patient to leave the hospital or doctor's office within a short time. These prior art casts do, however, suffer from lack of strength and porosity. This is particularly bothersomein the case of leg casts which must be weigllt-bearing in a relatively short time after application to permit the patient to walk around.
The present invention solves the aforementioned problem by provid-ing a plastic casting material which has improved strength. The casting materialof the invention provides improved strength and rididity within 20-30 minutes after application with a minimum of overlapping layers. The solution to the problem lies primarily in the scrim or tape material which is impregnated with the resin.
According to the present invention there is provided an orthopedic casting material cpmprising a fabric made from a fiber having an initial modulusof elasticity greater than 8 x 106 pounds per square inch. The fabric has a thickness between 0.020 and 0.045 inch and a mesh size of 20 to 200 opening per square inch and is impregnated with a reactive fluid resin which hardens by wetting with a curing agent. After wetting with the curing agent (e.g., by soaking for about 30 seconds in water) the material, when wrapped upon itself toform a cylindrical laminate of eight or less layers will have a load-bearing strength sufficient for weightbearing (for a 2-inch diameter cylinder, 20 poundsper inch of cylinder length) within 30 minutes after exposure to water.
The present invention further provides a method of forming an æ ~--~ - 5 -~1960 orthopedic cast on a body member comprising ihe steps of (1) covering the body mem~er with an inner protective sleeve comprising an air permeable fabric; and (2) wrapping the body member with an orthopedic casting material comprising a fabric made from a fiber having an initial modulus of elasticity greater than 8 x 106 pounds per square inch, the fabric having a thickness between 0.020 and 0.045 inch and a mesh size of 20 to 200 openings per square inch and a reactive fluid resin impregnated in the fabric which has been wetted with a curing agent to harden the resin after wrapping is completed.
The term "high modulus" as used herein to describe the fabric 10 component of the casting material refers the degree of resistance to deformation or bending and is expressed in terms of the modulus of elasticity. Modulus of elasticity is the ratio of change in stress to the change in strain which occurs when a fiber is mechanically loaded. The initial modulus of elasticity of the fiber should be greater than about 8 x 106 lbs/square inch. Such fibers include continuous filament E-fiberglass, polyaramid filament known as Kevlar ~49 (available from E.I. DePont de Nemours and Company), ceramic fibers such as Nextel ~ (available from 3M Company), continuous filament graphite such as Thornel ~ ~available from Union Carbide Corp.), boron fiber (such as may by Avco Corp.), and metal fibers such as stainless steel filaments which when fine enough can be formed into ~ - 6 -~7--fabrics by weaving or knitting. rrhese high modulus fibers impart a high degree of strength and rigidity to the cast.
They may be combined with low to intermediate modulus materials when the flexibility fo such yarns enables easier fabrication of the fabric Low modulus fibers are those havin~ an initial modulus of elasticity of less than about 3 x 106 lbs/in2 and include cotton, polyester (such as Dacron), polypropylene, Orlon, Dynel~ (Union Carbide), Nomex~ (Dupont) and nylon. An example of a fiber with an intermediate modulus is polyvinyl alcohol fiber known as Kuralon (available from Kuraray Co., Ltd.). Although hybrid fabrics are useful in making orthopedic casts a majority of high modulus fiber is necessary for adequate cast rigidity and strength.
The preferred fabric for use on the casting material of the invention is made of fiberglass fibers, particularly Raschel knit fiberglass fibers~ The Raschel knit fabric affords a lateral stretchability without lengthwise stretchability in the tape. Lateral stretch 20 provides a high degree of conformability to the body member. The resistance to lenythwise stretch in the tape is desiràble to prevent undesirable restriction of circulation within the body member.
The preferred fabric is a 3 bar Raschel knit of 25 18 gg knitted from a single fiberglass yarn construction called ECC 75 1/0 (available from Owen Corning). One yarn end is used per guide needle. Bar 1 executes a chain o stitch while bar 2 overlaps four needles. Bar 3 lays in a yarn longitudinally within each wale. This fabric is porous enough to allow water penetration of the cast and air circulation through the cast.
In addition to structural strength provided by the high modulus fiber, the fabric must have certain textural characteristics. The textural characteristics of the fabric, especially its surface area, porosity and thickness, affect the thoroughness and rapidity with which the curing agent becomes mixed or dissolved in the resinous component impregnated into the fabric. In one extreme in which the curing agent e.g., water, contacts only the surface of the resin, the surface of the resin would become hardened, but the resin would remain fluid below the hardened surface and not contribute to the strength of the cast. Furthermore, the hardened surface often impedes the permeation of the curing agent into the bulk of the still fluid resin. In such a case the desired rapid hardening is not achieved, and the bulk of the resin may never become hard because the surface is impenetrable to the curing agent. It has been discovered that such behavior can be avoided if the resinous layer is kept thin. This can be achieved at useful loadings of resin into the fabric if the fabric is selected to be thin and to have a high surface-to-volume ratio.
In determining the optimum thickness of the fabric, the need to keep the resinous layer thin to _9_ promote complete curing must be balanced with the need to minimize the number of layers in the cast. Practical considerations related to the ease of wrapping an orthopedic cast limit the number of layers of tape that it is convenient to apply. For most efficient cast application it is desired that the cast be comprised of no more than 6 to 8 layers of overlapping wraps of tape and preferably 4 to 5 layers of tape. A sufficient amount of material must be applied in these few layers to achieve the desired ultimate cast strength and rigidity. The thinner the fabric, the more wraps of tape have to be made to achieve adequate strength and rigidity. It has been foun~ that a fabric thickness between 0.020 and 0.045 inch and preferably between 0.022 and 0.035 inch, achieves the optimum balance between good resin curing and a minimum number of wraps.
The fabric should be a mesh, i.e., it should have openings through it to enable the curing agent to penetrate into the roll and expose all parts of the resin.
Openings in the fabric also facilitate circulation of air through the finished cast and evaporation of moisture from beneath the cast. This contributes to the patient's comfort and the maintenance of healthy skin under the cast, In the case of casting materials whose strength or rigidity is not degraded by exposure to water, cast porosity also enables rapid drying after bathing or following various forms of hydrotherapy or fluid rinsing 9~

for tissue debridement. The fabric should have a mesh size 20 to 200 openings per square inch, and preferably ~0 to 150 openings per s~uare inch.
I'he fabric used in the casting material is generally formed in rolls of various widths, generally from one inch to six inches wide. The fabric is impregnated with the curable resin material in an amount, in terms of volume, of from one to three times the volume of the material forming the fabric, and in the preferred embodiment employing a fiber~lass fabric of from 40% to 50% by weight of the impregnated casting material, The term "impregnate" is used to describe the condition in which the polymer is thoroughly intermingled with and in surrounding relation to the threads or fibers of the fabric and does not necessarily indicate that the resin is to any extent adsorbed by the fibers themselves.
Generally, the resin solution will flow into the capillary spaces between continguous filaments of the fabric and will become rigidly bonded to the fabric upon curing.
The amount of resinous component applied to the fabric must be sufficient for the formation of a strong interlayer laminate bond but not so much as to occlude the porosity and unnecessarily thicken the resin film which should be thin for rapid and complete hardening.
Excessive resinous component may also cause the casting tape to be messy to handle because of stickiness or drippng and transfer of resin.

~L5~960 The resin used in the casting material of the invention may be any curable resin which will satisfy the functional requirements of an orthopedic cast. Obviously, the resin must be nontoxic in the sense that it does not give off significant amounts of toxic vapors during curing which may be harmful to either the patient or the person applying the cast and also that it does not cause skin irritation either by chemical irritation or the generation of excessive heat during curing. Furthermore, the resin must be sufficiently reactive with the curing agent to insure rapid hardening of the cast once it is applied but not so reactive that does not allow sufficient working time to apply and shape the cast. Initially, the casting material must be pliable and formable and should adhere to itself. Then in a short time following completion of cast application, it should become rigid and strong to support loads and stresses to which the cast is subjected by the activities of the wearer. Thus, the material must undergo a change of state from a fluid-like condition to a solid, hard condition in a matter of minutes.
The preferred resins are those cured with water.
A number of classes of water~cured resins known in the art are suitable, including polyurethanes, cyanoacrylate esters, and, when combined with moisture sensitive catalysts, epoxy resins and prepolymers terminated at their ends with trialkoxy- or trihalo- silane groups. For example, U.S. Patent ~o. 3,932,526 discloses that iL~51''36(~
- 1?.-1,l-bis(perfluoromethylsulfonyl)-2-aryl ethylenes cause epoxy resins corltaining traces of moisture to become polymerized.
Resin systems other than those requiring 5 water-curing may be used, although the use of water to activate the hardening of an orthopedic castin~ tape is most convenient, safe and familiar to orthopedic surgeons and medical casting personnel. The principles disclosed herein regarding the modulus of elasticity, porosity and thickness of the fabric are applicahle to resin systems such as that disclosed in U.S. Patent No. 3,908,644 in which a ban~age impregnated with difunctional acrylates or methacrylates, such as the bis-methacrylate ester derived from the condensation of glycidyl methacrylate and bisphenol A (4,4'-isopropylidenediphenol). The resin is hardened upon wetting with solutions of a tertiary amine and an organic peroxide. Also, the water may contain a catalyst. ~or example, IJ.S. Patent No. 3,630,194 proposes an orthopedic tape impregnated with acrylamide monomers whose polymerization is initiated by dipping the bandage in an aqueous solution of oxidizing and reducin~ agents (known in the art as a redox initiator system). The strength, rigidity and rate of hardening of such a bandage is subject to the factors disclosed herein.
The preferred resins for use in the present invention are polyurethanes. Suitable polyurethane systems are discloed, for example in U.S. Patent No, ?6(:~

3,373,741 and in ~erman ~ffenlegunysschrift 2651089. The following disclosure relates primarily to the preferred embodiment of the invention wherein water-curable polyurethane resins are employed.
It is prefered to coat the res~n onto the fabric as a polyisocyanate prepolymer formed by the reaction of an isocyanate and a polyol. It is preferred to use an isocyanate which has low volatility such as diphenylmethane diisocyanate (MDI) rather than a more volatile material such as toluene diisocyanate (TDI).
Suitable isocyanates include 2,4-toluene diisocyante, 2,6-toluene diisocyanate, mixtures of these isomers,

4,4'-diphenylmethane diisocyanate, 2,4'-diphenylmethane diisocyanate, mixtures of these isomers together with possible small quantities of 2,2'-diphenylmethane diisocyanate (typical of commercially available diphenylmethane diisocyanate), and aromatic polyisocyanates and their mixtures such as are derived from phosgenation of the condensation product of aniline and formaldehyde. Typical polyols for use in the prepolymer system include polypropylene ether ~lycols (available from Union Carbide and from BASF Wyandotte under the tradename Pluracol~), polytetramethylene ether glycols (Polymeg~ from the Quaker Oats Co.), polycaprolactone diols (Niax~ PCP series of polyols from Union Carbide), and polyester polyols (hydroxyl terminated polyesters obtained from esterification of dicarboxylic

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acids and diols such as the Rucoflex~ polyols available from Ruco division, Hooker Chemicals CoO).
An especially preferred resin for use in the casting material of the invention uses an isocyanate known S as Isonate~ 143L available from ~he Upjon Company (a mixture containin~ about 73% of MDI) and a polypropylene oxide polyol froln BASF Wyandotte known as Pluracol~ P-710.
To prolong the shelflife of the material, it is preferred to include from 0.l to 1.0 percent by weight of benzoyl chloride or other suitable stabilizer.
The reactivity of the resin once it is exposed to the water curing agent can be controlled by the proper catalyst. The reactivity must not be so great that: (1) a hard film quickly forms on the resin surface preventing further penetration of the water into the bulk of the resin; or (2) the cast becomes rigid before the application and shaping is complete. Good results have been achieved using dimethylethanolamine (DMEA) as the catalyst in a concentration of about 1.8 percent by weight or more preferably a mixture of DMEA and amine bis-(dimethylamlno ethyl) ether at a concentration of 0.25 percent and 0.3 percent by weight, respectively.
Foaming of the resin should be minimized since it reduces the porosity of the cast and its overall strength. Foaming occurs because carbon dioxide is released when water reacts with isocyanate groups. One way to minimize foaming is to reduce the concentration of isocyanate groups in the prepolymer. However, to have reactivity, workability, optimum stickiness, and ultimate strength, an ade~uate concentration of isocyanate groups is necessary.
Although foaming is less at low resin contents, adequate resin content is required for desiable cast characteristics such as strength and resistance to unpeeling.
It has been found that most satisfactory method 0 of minimizing foaminq is to add a foam suppressor such as silicone Antifoam A (Dow Corning), ~B-100 silicone fluid (now Cornin~), silicone surfactants L550 or L5303 (Union Carbide), or organic surfactants such as LK-221~ (Air Products) to the resin. It is especially preferred to use a silicone liquid such as Dow Corning DB-100 at a concentration of about 0.1 to 1.0 percent by weight.
As normally packaged, the resin coated tape is in a roll wound up on a plastic core. For use, a roll is fully immersed in tap water for about 30 seconds. This is sufficient time for water to seep into the porous material and displace air, As long as the resin content is not too high to cause the openings in the fabric to be filled with resin, more than enough water is absorbed by the roll in this manner. When the roll is unwound during wrapping of the cast, the excess moisture coats freshly exposed resin surfaces insuring thorough wetting and rapid hardening of the cast.

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Prior to applying the orthopedic cast, an inner protective sleeve is positioned about the limb or body member of the patient. The sleeve takes the form of a tubular stockinet or some other convenient form such as, for example, an elongated strip or bandage which may be wrapped about the body member.
The inner protective sleeve preferably comprises an air permeable fabric whereby ventilating air may pass through both the sleeve and cast to the surface of the skin. Also, the sleeve preferably comprises a fabric which does not appreciably absorb water. This structure also permits the escape of perspiration which would otherwise tend to build up and produce skin irritaion and an unpleasant odor. Typically, the stockinet is a knitted or woven crystalline polypropylene material which is inherently nonwetting and permeable.
With the sleeve in a proper position, the moistened orthopedic cast material is wrapped about the body member and over the protective sleeve in a manner similar to the application of an elastic-type bandage.
The cast is shaped in a manner similar to the shaping of a plaster-of-paris cast.
Eight or less layers of the cast material should be sufficient to form a cast having weight-bearing strength within 30 minutes, i.e., a cylindrical laminate having eight or less layers should support 20 pounds of pressure per inch of cylinder length. This test to

6() determine weight-bearing strength is discussed more fully below in Example 1.
The invention may be further illustrated by the following non-limiting examples. The resin component used in these examples is based on a moisture-curing polyurethane prepolymer but one of a number of other moisture-curing systems could be used.
Three different moisture hardening polyurethane prepolymers are used in the examples and were formulated as follows:
Resin A
A moisture curing polyurethane prepolymer was prepared frcm Desmodur~ E-21 commercially available from Mobay chemical Corp. Desmodur~ E-21 is an aromatic polyisocyanate prepolymer (a mixture of p,p'-diphenylmethane diisocyanate and higher homologs) having an average equivalent weight per isocyanate group of 262 and an isocyanate content (% NCO by weight) of about 16%. It is a brown, viscous liquid. To 1000 g of Desmodur~ E-21 stirred and protected from moisture was added dropwise 10.0 ml of M,N-dimethylethanolamine to give a homogeneous mixture. No polyol was employed in this formulation.
Resin B
A polyurethane prepolymer was prepared by reaction cf p,p'-diphenylmethane diisocyanate with a poly(oxypropylene) diol to produce a viscous liquid o -l8-suitable for impregnating the fabrics. A commercial form of p,p'-diphenylmethane diisocyanate was used known as Isonate~ 143L available from the Upjohn Company. Isonate~
143L is an equilibrium mixture at room temperature containing about 73~ of p,p'-diphenylmethane diisocyanate.
To 300 g of Isonate~ 143L protected from moisture under a dry nitro~en atmosphere was added slowly while stirring a solution of 5.0 ml of N,N-dimethylethanolamine in 200 g of Pluracol~ P-710, a polypropylene glycol available from BASF Wyandotte Corp., having an approximate averaye molecular weight of 77S and a hydroxyl nurnber of 145. The rate of addition was adjusted to maintain the temperature of the mixture below 50C. The resulting polyurethane prepolymer had lS approximately 12.5% NCO.
Resin _ Resin C is identical to Resin B except that a mxiture of two tertiary amines was used as a catalyst consisting of 1.25 ml of N,N-dimethylethanolatnine and 1.5 ml of 2,2'-oxybis-(N,N-dimethylethylamine). An antiforminy agent ~B-100, Dow Corning) and a stabilizer benzoyl chloride each at 0.2 percent by weight were also included.
The characteristics of the uncoated fabrics used in the examples are summarized in Table I.

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~ t, o Fabrics were oven dried beEore impregnating withresin and were coated with resin promptly after removal from the oven. Fiberglass fabrics were dried overnight at 160 to 180C. Synthetic fabrics were dried overnight at 120C. Resin mixtures to be coated on these fabrics were formulated in a dry box with a relative humidity less than 5% at ambient temperature. Coatings were carried out in a dry atmosphere with a relative humidity less than ~0%.

Resin was applied to the fabrics using either a two-roll squeeze coater or a nip-fed kiss-roll coater. The amount of resin applied was controlled by the choice of the temperature of the resin when coated, by the setting of gap between the two coating rollers oE the squeeze coater or the gap between the Doctor hlade and the single roller of the nip-fed kiss-roll coater, and by adjusting the speed of the moving weh. AEter coating, the resin content of the resin impregnated fiberglass fabrics was determined by the weight lost when a sample was burned in air in a muffle furnace held at 700C. For the combustible synthetic fabrics, resin content was determined by extraction of the resin from a weighed sample of coated fabric using a solvent such as toluene and then weighing the dried (to a constant weight) fabric, _XAMPLæ 1 This example is included ~or purposes of comparison. The fabric used is illustrative of the prior art and does not meet the criteria established Eor the present invention.

A three inch wide strip of the polyester/cotton Fabric F was coated with a prepolymer corresponding to Resin A to give an adhesive tape containing 53 to 54~ by weight of the resin. Four yard lengths of tape were wound on plastic cores of 1/2 inch diameter into rolls. ~ach roll was sealed in a moisture impermeable pounch for storage. The hardening and strength properties of the tape were determined by forming cyclinder casts from the moistened tape and then measuring the load bearing ability 15 minutes and 24 hours later. According to the procedure, a roll of tape was removed from its pouch, immersed in room temperature tap water for 30 seconds and then wrapped into a 3-inch long (the width fo the tape) cylinder on a 2-inch diameter mandrel. After a time of 15 minutes or 24 hours (measured from the beginning of the 30 second immersion period), compressive loads were applied to the cylinder cast along its exterior and parallel to its axis. The cylinder was supported in a fixture with two "knife" (1/8 inch radius) edges spaced 1.6 inches apart parallel to the cylinder axis. A third "knife" edge was centered over the top of the cylinder also parallel to the axisA Force was applied to the cylinder along the o knife edges. The maximum load capable of being sustained was measured using a Dillon dynamometer, The results for casts of various layers are reported in the following Table II.

TABLE II

Rigidity of Cylinder Casts from Synthetic Fabric of Example 1 Compressive Lcad Bearing Ability Number of pounds per inch of cast length Weight of 10layers in15 min. after24 hr. after 3" lon~, 2" diam.
cast immersiona immersionb cylinder cast, g 1.9 3.3 10.6 8 6.0 9.3 17.0 12 15.5 22.9 25.8 1516 -- 41.3 35.8 a. Average of8 determinations b. Average of4 determinations except for 16 layer ring which was a single sample.

It is evident that in every case the 15 minute value is more than 50% of the 24 hour value indicating that a substantial fraction of the water induced polymeri-zation has occurred by 15 minutes. ~owever, until 12 or more layers of the tape have been applied, the rigidity is not sufficient for most orthopedic casting applications, i.e., about 20 lbs/inch or more of load bearing ability as measured by this test. The following example shows that sufficient load bearing can be obtained with fewer layers using a fabric according to the present invention.

~51S~60 Under dry conditions, freshly oven dried fiberglass (Fa~ric A, 3 inches wide) was impregnated (using a two roller coater head) with Resin A to obtain a resin content of 45.8~ as a percent by weight of the coated tape. Four-yard long rolls were prepared and packaged as described in Example 1. Following a 30-second immersion of a roll in tap water, 5 lay;er cylinder casts of 2-inch inside diameter were made and tested at various time intervals for load bearing ability (as described in Example 1). These results are summarized in the following Table III.

TABLE III
Rigidity of Cylinder Casts * from Tape of Exam~le 2 Time AfterCompressive Load pounds/inch Immersionof cylinder length 15 min. 8.7 30 min. 15.7 60 min. 23.0 24 hr. 50.2 * Five layer cylinder casts 3 inches long and 2 inches in diameter were made immediately after immersion of a roll of tape in 80F water for 30 seconds. Each value is for one cast except the 24-hour value which is the average of 6 samples. The average weight of these casts when dry was 40.2 g.
The foregoing data indicate:

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1. ~he 15 minute rigidity greatly exceeds that for a 5-layer cylinder cast of Example 1.
2. The load bearing ability exceeds 20 lhs/inch after about 1 hour.
3. The 15 minute load is only 17% of the overnight value, which indicates that at 15 minutes significant hardening has still to take place.

A 3 inch wide strip of freshly dried Fabric B
was impregnated with Resin A yielding a tape containing 46.1% by weight of resin. Cylinder casts were made immediately from a 4-yard roll of tape following a 30 second immersion in 80F water. The load bearing ability was measured as in Example 1 at various time intervals following immersion. The results are summarized in the following Table IV.

5~l960 -2~-TABLE_IV
dit~ of_~linder Casts * from Tape of E~ele 3 Time After Compresive Load pounds/inch Immersion _ of cylinder length 15 min. ~.3 30 min, 13.3 60 min. 21.0 24 hr. 58.4 * Five layer cylinder casts 3 inches long and 2 inches in diameter. ~he average weight of dry casts was 44.8 g.

Comparison with Table III shows that although the 24 hour rigidity has increased due to the increased weight of the fabric, the 15-minute rigidity is slightly reduced below that for the thinner Fabric ~. The increased fiberglass thickness and the slightly decreased mesh number that introduces more material in each layer of a cast decreases the rate of hardening.

This example shows the effect of variations in fabric parameters, i.e., mesh size and thickness upon the rate of hardening and rigidity of the finished cast.
Dried fiberglass Fahrics A through E of Table I
were individually coated with Resin B. Resin contents were held as closely similar as possible, although fabric C, due to its low surface area, was not easy to ~5~ 60 impregnate, Cylinder casts were made immediately after a 30-second immersion in water at 80F.
Because of the diEferent thicknesses of fabrics, different numbers of layers were used to obtain cylinder casts of comparable weight. Thus, five layers for Fabrics A and B corresponded to 4 layers for Fabric C (the thickest fabricl and 6 layers for Fabrics D and E. Load bearing was determined as in Example 1, 15 minutes, 30 minutes and 24 hours following immersion. The results are summarized in the following Table V.

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~9 These fabrics fall into three classes with respect to their ~urface area to volume ratios. Fabric C
has the lowest surface area per unit volume (approxiamtely 320 in2/in3). Fabrics A and B have an intermediate value S (about 390 in2/in3) and Fabrics n and E have the highest surface to volume ratio (about 54~ in2/in33, The rate at which rigidity is developed shortly after exposure to water differs for these classes of fabrics. This can be seen by comparing the ratio fo the 15-minutes rigidity to the 24-hour ri~idity (divided by cast wei~ht) as shown in the following Table VI (usinq the data of Table V).
Another correlation to early development of rigidity for this example is the mesh number divided by the approximate wale thickness (shown in Table VI, also).

~ABIE VI
Early Ri~idity (15 min. Rigidity) Approximate Mesh Number (24 hr. Rigidlty) Mesh Wale Wale FabricCast Weight N~r Thickness Thickness 20 A 0.0103 90 0.028 3200 B 0.0092 80 0.030 2700 0.0151*
C 0,0037 35 0.051 690 D 0.0234 140 0.023 6100 25 E 0.0160 130 0.02~ 4600 0,0211*
0.0226*

* Results from Example 5 below.

It is evident also from Table V that with Fabrics D and E, rno~e than 20 lbs/inch of rigidity are developed in a 6 layer cast within 30 minutes, which exceeds the previously stated criterion for orthopedic cast function. With Fabrics A-D, a greater number of layers is requried for finished casts meeting this criterion.

The factors aEfecting fabric choice apply when the prepolymer is more reactive. This is shown by using Resin C which contains two amine catalysts. The combination of catalysts causes polymerization to be faster than for Resin B.
~abrics B and E were impregnated with Resin C, and cylinder casts were made (5 layers for Fabric B and 6 layers for Fabric E). The rigidities attained within 15 minutes are improved over Resin B (Table V), but the coarser, thicker Fabric B still lags behind Fabric E when corrections for cast weight are made. The results are summarized in the following Table VII.

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m EXAMPI,E 6 This example sllows that in the case of another high modulus fiber, namely Kevlar~ 49, the fabric properties are again important in determining the rate of cast rigidification. This example also compares the relative performance in a cast of fibers of high modulus and of low mo~ulus.
Fiberglass Fabric C and synthetic fabircs G, H, I and J, were dried and impregnated with Resin C as previously described. The specific gravity and initial modulus of elasticity for the various fibers are given in the following Table IX.

TA~LE IX

Fiber ProPerties Initial Modulus Specific of Elasticity Fiber Gravity lbs/in2 x 10~
_________________________________________________________ Revlar~ 49 1.44 18 E-Fiberglass 2.54 10 Kuralon PVA 1.26 3.0 Dacron~ 1.38 2.0 Cotton 1.71 1.0 Nylon 1.14 0.6 Since the specific gravities of the various fibers difEer, resin contents were adjusted so that they were comparable on a volume basis, i.e., the ratio of the -33~

volume of resin to ~he volume of fabric is comparable from fabric to ~abric~ and the resin available to form interlaminate bonds is approximately equivalent in amount.
Fabrics G (Kevlar~ 49) and E (fiber~lass) are of comparable knit structure. Therefore, casts of six layers were made from resin-impregnated Fabric G for comparison with those of Example 5 of Fabric E. Fabrics H (Kevlar3 49), C (fiberglass)~ and I (nacron~) were similarly of comparable knit patterns so that cylinder casts of 5 layers were made from each. Fabric J (nylon/polyester) is a lighter weight fabric than the others and has a finer mesh. Consequently, cylinders of 10 and 20 layers were fabricated from it. The rigidities of these casts are reported in the following Table X.

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The casts of the two Kevlar~ 49 fabrics are of comparable weight, so a comparison of absolute rigidities is meaningful. ~able X shows that while the overnight rigidities of the two materials are similar, the rigidity attained 15 minutes following wetting with water is substantially higher for Fabric G, the thinner, finner mesh fabric. Table IX indicates that Revlar~ 49 has a somewhat higher modulus of elasticity than fiberglass so that it would be expected that Kevlar containing casts would have higher rigidities than for similar structured fabrics constituted of fiberglass. This is, indeed, the case as shown by a comparison of rigidities in Table X;
casts of Fabric G support higher loads than for Fabric E.
Fabric H supports more than wili its glass counterpart, Fabric C, of equivalent cast weight.
The lower modulus fibers do not produce acceptably rigid casts. Thus, Fabric I of ~acron~ does not compare favorably with similar structure Kevlar~ 49 or fiberglass fabrics when used in a cast. The thin, fine mesh Fabric J, although achieving about 30% oE its ultimate rigidity in the first 1~ minutes following wetting with water, does not produce a rigid cast with even 10 layers of material. ~ cast with rigidity comparable to that produced by Fabric G would not only require numerous (about 20) layers of Fabric J, but the cast would be heavier than the Kevlar~ 49 or fiberglass cast despite the lower specific gravity of the nylon/polyester fiber combination.
Another disadvantage of Fabric J was that it gave casts that were occluded and not porous. This is due to the high mesh number of this fabric coupled with the large number of overlapping layers needed in the cast.
Furthermore, water did not completely penetrate the roll of impregnated tape when it was dipped in water; it was necessary to wet each layer individually with water as this tape was wrapped into a cast rendering cast application inefficient.

Example 7 This example examines a wider range of fiberglass fabrics. The extrernes of the range are represented by Fabric K (finest) and Fabric L ~coarsest) whose characteristics are listed in Table I. Dried Fabrics K, E, C and L were impregnated as described in previous examples with Resin ~ (~esmodur~ E-21 containing 1 ml of N,N-dimethylethanolamine per 100 g of resin).
Fabrics A and B had been coated previously with resin A
(Exampes 2 and 3). Cylinder casts were made promptly following wetting of ~he tape with water. The load bearing abilities were measured as described previously.
Results obtained are summarized in the following Table XII
in order of increasing fabric coarseness, iOe., increasing thickness and openness. Data from Examples 2 and 3 are included for comparison.

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d er The finer mesh, thinner fabrics listed first in the table attain rigidity faster for a given weight of cast material than the coarser ones, with Fabric K being fastest. However, Fabric K produces a cast that is not porous whereas all other fabrics of Table XII gave excellent air permeability and porosity. With mesh numbers greater than about 200, casts will not be porous.

Example 8 This example illustrates the factors affecting the porosity of casting tapes made with Fabric K. Dry fabric K was coated with Resin C as described previously with various coating speeds and gap settings to obtain tapes with differing resin contents. The following Table XIII gives resuts for water taken into the roll upon immersion, cast rigidities, and other properties relating to porosity and strength. When the resin content was reduced enough to achieve some cast porosity, the test casts were very weak even after 24 hours and delaminated.
When the resin content was raised in order to make sufficiently strong casts, all porosity was lost.

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Claims

915,738 WHAT IS CLAIMED IS:

1. An orthopedic casting material comprising a fabric made from a fiber having an initial modulus of elasticity greater than 8 x 106 pounds per square inch, said fabric having a thickness between 0.020 and 0.045 inch and a mesh size of 20 to 200 openings per square inch and a reactive fluid resin impregnated in said fabric which hardens when said resin is wetted with a curing agent.

2. The orthopedic casting material according to claim 1 wherein said resin hardens when wetted with water.

3. The orthopedic casting material according to claim 2 wherein said casting material when exposed to water for at least 30 seconds and wrapped upon itself to form a 2-inch diameter cylindrical laminate of eight or less layers has a load-bearing strength of 20 pounds per inch of cylinder length within 30 minutes following exposure to water.

4. The orthopedic casting material according to claim 2 wherein said resin is a polyisocyanate prepolymer.

5. The orthopedic casting material according to claim 4 wherein said polyisocyanate prepolymer comprises polypropylene oxide polyol encapped with diphenylmethane diisocyanate.

6. The orthopedic casting material according to claim 2 wherein said resin further comprises a preservative to retard hardening prior to use.

7. The orthopedic casting material according to claim 6 wherein said preservative is benzoyl chloride.

8. The orthopedic casting material according to claim 4 wherein said resin further comprises an anti-foaming agent.

9. The orthopedic casting material according to claim 8 wherein said anti-foaming agent is a silicone.

10. The orthopedic casting material according to claim 4 wherein said resin further comprises a catalyst to control hardening time.

11. The orthopedic casting material according to claim 10 wherein said catalyst is dimethylethanolamine.

12. The orthopedic casting material according to claim 11 wherein said catalyst is a mixture of dimethylethanolamine and amino bis-(dimethylaminoethyl) ether.

13. An orthopedic casting material according to claim 1 wherein said fiber is fiberglass.

14. An orthopedic casting material according to claim 13 wherein said fiberglass is E fiberglass.

15. An orthopedic casting material according to claim 14 wherein said fiberglass is ECC-150 or ECC-75.

16. An orthopedic casting material according to claim 1 wherein said fabric thickness is between 0.022 and .035 inch.

17. An orthopedic casting material according to claim 1 wherein fabric has a mesh size of 80 to 150 openings per square inch.

18. A method of forming an orthopedic cast on a body member comprising the steps of:
1. covering said body member with an inner protective sleeve comprising an air permeable fabric; and 2. wrapping said body member with an orthopedic casting material comprising a fabric made from a fiber having an initial modulus of elasticity greater than 8 x 106 pounds per square inch, said fabric having a thickness between 0.020 and 0.045 inches and a mesh size of 20 to 200 openings per square inch and a reactive resin impregnated in said fabric which has been wetted with a curing agent to harden said fluid resin after said wrapping is completed.

19. The method according to claim 18 wherein said resin is a polyisocyanate prepolymer which has been wetted with water.

20. The method according to claim 18 wherein said fabric is fiberglass.