CA1136990A - Anti-hemorrhagic and anti-inflammatory oral rinse - Google Patents
Anti-hemorrhagic and anti-inflammatory oral rinseInfo
- Publication number
- CA1136990A CA1136990A CA000356955A CA356955A CA1136990A CA 1136990 A CA1136990 A CA 1136990A CA 000356955 A CA000356955 A CA 000356955A CA 356955 A CA356955 A CA 356955A CA 1136990 A CA1136990 A CA 1136990A
- Authority
- CA
- Canada
- Prior art keywords
- oral rinse
- potassium chloride
- hemorrhagic
- rinse
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
Abstract
ABSTRACT OF THE DISCLOSURE
An oral rinse having anti-hemorrhagic and anti-inflammatory properties includes, as active ingredients, a homogeneous, synergistic mixture of approximately 95% of the hydrate of magnesium sulphate, approxi-mately 4% sodium bicarbonate, the remainder being potassium chloride or a mixture of equal parts of potassium chloride and sodium chloride.
An oral rinse having anti-hemorrhagic and anti-inflammatory properties includes, as active ingredients, a homogeneous, synergistic mixture of approximately 95% of the hydrate of magnesium sulphate, approxi-mately 4% sodium bicarbonate, the remainder being potassium chloride or a mixture of equal parts of potassium chloride and sodium chloride.
Description
- ~13~
This invention relates to an oral rinse, and in particular to an oral rinse having anti-inflammatory and anti-hemorrhagic properties.
Usually, following periodontal surgery such as a gingivectomy, no mouthwash or oral rinse is recommended except perhaps common table salt and water. There are antibacterial mouthwashes avai lable such as, for example, the one sold under the trade mark Cepacol, which contains cetylpyridinium as an active ingredient. However, other than a mi Id anti-bacterial action, such mouthwashes are, at best, breath fresheners.
Accordingly, there exists a need for a mouthwash or oral rinse 10 which can be used after oral surgery to reduce hemorrhaging and to promote the healing process, and if used daily in cases where a chronic periodontal condition exists it acts as an excellent prophylactic measure. The object of the present invention is to provide such a rinse.
Accordingly, in its simplest form the present invention relates to an oral rinse including a homogeneous mixture of the hydrate of magnesium sulphate, sodium bicarbonate and potassium chloride as the active ingredients.
More specifically, the present invention relates to an oral rinse including, as active ingredients, from 92 to 97% by volume of the hydrate of magnesium sulphate, from 3 to 8% by volume sodium bicarbonate, the remainder 20 being potassium chloride. One preferred formulation includes equal parts of sodium chloride and potassium chloride. The sodium chloride could be com-pletely replaced by potassium chloride in cases where the user is on a salt-free diet, e. 9., in cases of high blood pressure. Of course, taste and flavour additives are added to make the rinse palatable. Such additives include oil of peppermint and artificial sweeteners.
In use, the formulation described above is dissolved in water, preferably warm water and used to rinse the oral cavity. It should be noted that none of the active ingredients is toxic. The only powder oral rinses on the market today are toxic if swal lowed and are label led as such. More-' over, the rinse contains no prescription drugs.
_l_ ~3~0 The sodium bicarbonate acts as a buffering agent, adjusting the pH of the rinse to an acceptable level.
The inventor found that the hydrate of magnesium sulphate possesses anti-hemorrhagic and anti-inflammatory properties when administered orally in a rinse. Such properties are enhanced by the other additives, i. e., the potassium chloride and sodium chloride. In other words, there is synergism.
A typical formulation of the oral rinse on a small scale is as fo I I ows:
APP ROX I MAT E
INGREDIENT % BY VOUME
8 tablespoons of the hydrate of magnesium sulphate (MgSO4. 7H2O) U. S. P. 95. 33 1 teaspoon of sodium bicarbonate (NaHCO3) 4 1/12 teaspoon of sodium chloride (NaC1) and 1/12 teaspoon of potassium chloride (KC1) or 1/6 teaspoon of sodium chloride 0. 66
This invention relates to an oral rinse, and in particular to an oral rinse having anti-inflammatory and anti-hemorrhagic properties.
Usually, following periodontal surgery such as a gingivectomy, no mouthwash or oral rinse is recommended except perhaps common table salt and water. There are antibacterial mouthwashes avai lable such as, for example, the one sold under the trade mark Cepacol, which contains cetylpyridinium as an active ingredient. However, other than a mi Id anti-bacterial action, such mouthwashes are, at best, breath fresheners.
Accordingly, there exists a need for a mouthwash or oral rinse 10 which can be used after oral surgery to reduce hemorrhaging and to promote the healing process, and if used daily in cases where a chronic periodontal condition exists it acts as an excellent prophylactic measure. The object of the present invention is to provide such a rinse.
Accordingly, in its simplest form the present invention relates to an oral rinse including a homogeneous mixture of the hydrate of magnesium sulphate, sodium bicarbonate and potassium chloride as the active ingredients.
More specifically, the present invention relates to an oral rinse including, as active ingredients, from 92 to 97% by volume of the hydrate of magnesium sulphate, from 3 to 8% by volume sodium bicarbonate, the remainder 20 being potassium chloride. One preferred formulation includes equal parts of sodium chloride and potassium chloride. The sodium chloride could be com-pletely replaced by potassium chloride in cases where the user is on a salt-free diet, e. 9., in cases of high blood pressure. Of course, taste and flavour additives are added to make the rinse palatable. Such additives include oil of peppermint and artificial sweeteners.
In use, the formulation described above is dissolved in water, preferably warm water and used to rinse the oral cavity. It should be noted that none of the active ingredients is toxic. The only powder oral rinses on the market today are toxic if swal lowed and are label led as such. More-' over, the rinse contains no prescription drugs.
_l_ ~3~0 The sodium bicarbonate acts as a buffering agent, adjusting the pH of the rinse to an acceptable level.
The inventor found that the hydrate of magnesium sulphate possesses anti-hemorrhagic and anti-inflammatory properties when administered orally in a rinse. Such properties are enhanced by the other additives, i. e., the potassium chloride and sodium chloride. In other words, there is synergism.
A typical formulation of the oral rinse on a small scale is as fo I I ows:
APP ROX I MAT E
INGREDIENT % BY VOUME
8 tablespoons of the hydrate of magnesium sulphate (MgSO4. 7H2O) U. S. P. 95. 33 1 teaspoon of sodium bicarbonate (NaHCO3) 4 1/12 teaspoon of sodium chloride (NaC1) and 1/12 teaspoon of potassium chloride (KC1) or 1/6 teaspoon of sodium chloride 0. 66
2 drops of peppermint oil 4 crystals of menthol U. S. P. ground into a powder 0. 4 gram of artificial sweetener - (in this case the sweetener is sodium cyclamate) In the foregoing list of ingredients, the percentages by volume are given only for active ingredients, i. e., the percentages are based on the total volume of active ingredients only. The percentages by volume of active ingredients can be varied by ~ 3-5%. While only two flavour and taste ingredients are mentioned, it will be appreciated that other agents of the type commonly used in mouthwash preparations can be incorporated in the oral rinse of the present invention.
Claims (5)
1. An oral rinse comprising an homogenous mixture of from 92 to 97 percent by volume of a hydrate of magnesium sulphate, from 3 to 3 percent by volume of sodium bicarbonate, and added thereto up to about 1 percent of at least one salt selected from the group consisting of potassium chloride and sodium chloride.
2. An oral rinse according to claim 1, said salt being potassium chloride.
3. An oral rinse according to claim 2, said potassium chloride being present in the amount of approximately 1 percent.
4. An oral rinse according to claim 1, the composition including both potassium chloride and sodium chloride.
5. An oral rinse according to claim 4, wherein both potassium chloride and sodium chloride are present in the amount of one half percent each.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000356955A CA1136990A (en) | 1980-07-24 | 1980-07-24 | Anti-hemorrhagic and anti-inflammatory oral rinse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000356955A CA1136990A (en) | 1980-07-24 | 1980-07-24 | Anti-hemorrhagic and anti-inflammatory oral rinse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1136990A true CA1136990A (en) | 1982-12-07 |
Family
ID=4117505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000356955A Expired CA1136990A (en) | 1980-07-24 | 1980-07-24 | Anti-hemorrhagic and anti-inflammatory oral rinse |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA1136990A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984001713A1 (en) * | 1982-11-03 | 1984-05-10 | Chemical Dynamics Sweden Ab | Control of microflora and preparations therefor |
| WO1985003224A1 (en) * | 1984-01-27 | 1985-08-01 | Goldemberg Robert L | Dental rinse |
| US4657758A (en) * | 1984-01-27 | 1987-04-14 | Oral Research Laboratories, Inc. | Dental rinse |
| US5085853A (en) * | 1991-06-24 | 1992-02-04 | Chesebrough-Pond's U.S.A., Division Of Conopco, Inc. | Flavor for peroxide-bicarbonate oral compositions |
| GB2571766A (en) * | 2018-03-08 | 2019-09-11 | Riza Zhubi Fatos | Dental composition and dental paste comprising same |
-
1980
- 1980-07-24 CA CA000356955A patent/CA1136990A/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984001713A1 (en) * | 1982-11-03 | 1984-05-10 | Chemical Dynamics Sweden Ab | Control of microflora and preparations therefor |
| WO1985003224A1 (en) * | 1984-01-27 | 1985-08-01 | Goldemberg Robert L | Dental rinse |
| US4657758A (en) * | 1984-01-27 | 1987-04-14 | Oral Research Laboratories, Inc. | Dental rinse |
| US4666708A (en) * | 1984-01-27 | 1987-05-19 | Oral Research Laboratories, Inc. | Dental rinse |
| US5085853A (en) * | 1991-06-24 | 1992-02-04 | Chesebrough-Pond's U.S.A., Division Of Conopco, Inc. | Flavor for peroxide-bicarbonate oral compositions |
| US5186926A (en) * | 1991-06-24 | 1993-02-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Flavor for peroxide-bicarbonate oral compositions |
| GB2571766A (en) * | 2018-03-08 | 2019-09-11 | Riza Zhubi Fatos | Dental composition and dental paste comprising same |
| GB2571766B (en) * | 2018-03-08 | 2022-05-25 | Riza Zhubi Fatos | Dental composition and dental paste comprising same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |