CA1025359A - Microencapsulated medical powders - Google Patents

Microencapsulated medical powders

Info

Publication number
CA1025359A
CA1025359A CA171,807A CA171807A CA1025359A CA 1025359 A CA1025359 A CA 1025359A CA 171807 A CA171807 A CA 171807A CA 1025359 A CA1025359 A CA 1025359A
Authority
CA
Canada
Prior art keywords
microencapsulated
medical powders
powders
medical
microencapsulated medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA171,807A
Other languages
French (fr)
Other versions
CA171807S (en
Inventor
Harry Seager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of CA1025359A publication Critical patent/CA1025359A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043—Drying and spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent
CA171,807A 1972-05-19 1973-05-18 Microencapsulated medical powders Expired CA1025359A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2357672A GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments

Publications (1)

Publication Number Publication Date
CA1025359A true CA1025359A (en) 1978-01-31

Family

ID=10197917

Family Applications (1)

Application Number Title Priority Date Filing Date
CA171,807A Expired CA1025359A (en) 1972-05-19 1973-05-18 Microencapsulated medical powders

Country Status (16)

Country Link
JP (2) JPS4954518A (en)
AR (1) AR197900A1 (en)
AT (1) AT337902B (en)
AU (1) AU475493B2 (en)
BE (1) BE799783A (en)
CA (1) CA1025359A (en)
DE (1) DE2325410A1 (en)
DK (2) DK134424B (en)
ES (1) ES414908A1 (en)
FR (1) FR2185390B1 (en)
GB (1) GB1403584A (en)
HU (1) HU167559B (en)
IE (1) IE37637B1 (en)
IL (1) IL42312A (en)
NL (1) NL7307033A (en)
ZA (1) ZA733406B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4940588A (en) * 1984-10-30 1990-07-10 Elan Corporation Controlled release powder and process for its preparation

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments
GB1532993A (en) * 1975-03-07 1978-11-22 Beecham Group Ltd Injectable antibiotic compositions
JPS5446001U (en) * 1977-09-07 1979-03-30
FR2403080A1 (en) * 1977-09-15 1979-04-13 Heyden Chem Fab Slow-release nitro:furantoin compsn. useful as urinary antiseptic - comprises three types of granulate with different solubilities
DE2805106A1 (en) * 1978-02-07 1979-08-16 Hoechst Ag MICROCAPSULES MADE OF POLYVINYL ALCOHOL WITH LIQUID, WATER-INSOLUBLE FILLING MATERIAL AND PROCESS FOR THEIR PRODUCTION
JPS56156214A (en) * 1980-05-02 1981-12-02 Yoshiaki Kawashima Preparation of tableting enteric microcapsule
JPS5867616A (en) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd Enteric microcapsule and its preparation
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
SE8404808L (en) * 1983-10-03 1985-04-04 Avner Rotman MICROCAPCLE PLATE MEDICINE IN SOT MATRIX
JPS61218516A (en) * 1985-03-25 1986-09-29 Ichimaru Fuarukosu Kk Production of sustained release microcapsule
IT1230095B (en) * 1989-04-27 1991-10-05 Parenta Srl PROCEDURE FOR THE PREPARATION OF STERILE FORMS OF INJECTABLE POWDERS OF ANTIBIOTICS.
DK0492007T3 (en) * 1990-11-29 1995-06-26 Faulding F H & Co Ltd Process for preparing liquid-filled powders
SE9903236D0 (en) * 1999-09-10 1999-09-10 Astra Ab Method of obtaining microparticles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112083A (en) * 1970-09-16 1972-03-20
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4940588A (en) * 1984-10-30 1990-07-10 Elan Corporation Controlled release powder and process for its preparation
US4952402A (en) * 1984-10-30 1990-08-28 Elan Corporation, P.L.C. Controlled release powder and process for its preparation

Also Published As

Publication number Publication date
DK134424C (en) 1977-05-23
DE2325410A1 (en) 1973-11-29
FR2185390B1 (en) 1977-04-15
IE37637L (en) 1973-11-19
FR2185390A1 (en) 1974-01-04
AU5596573A (en) 1974-11-21
IL42312A0 (en) 1973-07-30
AR197900A1 (en) 1974-05-15
AU475493B2 (en) 1976-08-26
ES414908A1 (en) 1976-06-01
AT337902B (en) 1977-07-25
ZA733406B (en) 1975-03-26
HU167559B (en) 1975-11-28
BE799783A (en) 1973-11-19
DK134423C (en) 1977-04-12
DK190774A (en) 1975-10-06
DK134423B (en) 1976-11-08
JPS4954518A (en) 1974-05-27
NL7307033A (en) 1973-11-21
DK134424B (en) 1976-11-08
JPS49116220A (en) 1974-11-06
IE37637B1 (en) 1977-09-14
ATA439473A (en) 1976-11-15
GB1403584A (en) 1975-08-28
IL42312A (en) 1977-01-31

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